Bioassay Methods Group

The Bioassay Methods Group develops and applies standards and methods for all analytical and bioanalytical measurements pertinent to instrument calibration and validation to ensure bioassay performance for identification and quantitation of molecular and biological species.

Projects/Programs

Precision Medicine for Cancer Diagnostics—The conventional approach to medicine is rapidly changing to a data-driven strategy in which therapies are individually targeted to a patient based on genome, physiology, environment, or lifestyle...

Measurement of Low Frequency Mutations in Circulating Tumor DNA (ctDNA) through Interlaboratory Testing—A very exciting development in the diagnosis and therapeutic monitoring of cancer is the discovery that blood and urine contain nucleic acids derived from cancer cells that can be used to as biomarkers...

Quantitative Flow Cytometry—We work in collaboration with other government agencies, private industry, academia, professional societies, and other national metrology institutes to ensure that flow cytometry measurements are …

Thermodynamics of Enzyme-catalyzed Reactions—To develop the thermodynamic data and methodology required for effective bioprocess engineering...

Quantification of Cells with Specific Phenotypic Characteristics—Flow cytometers are versatile instruments that have been successfully used to enumerate cell subsets in infectious diseases (e.g., HIV) and to diagnose malignancies through changes in the …

Contact

Group Leader