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Linhua Tian (Fed)
Biologist
RESEARCH INTERESTS
My work currently focuses on using state of the art immunological techniques to develop methods, protocols and reference materials to advance applications in the following areas:
- Immunotherapy and T cell immunology
- Viral vector characterizations for cell therapy and gene therapy
- Biomarkers and precision medicine
- Quantitative flow cytometric measurements
- Polychromatic flow cytometry standardization
- Flow cytometry data harmonization
- Equivalent number of reference fluorophores (ERF) assignments
- High-throughput screening and automation
PUBLICATIONS
Zamisch M, Tian L, Grenningloh R, Wildt WF, Enlers M, Ho IC and Bosselut R. The transcription factor ETS1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus. J Exp Med 2009 Nov 23, 206(12): 2685-99.
Wang T, Tian L, Haino M, Gao JL, Lake R, Ward Y, Wang H, Siebenlist U, Murphy PM, Kelly K., Improved Antibacterial Host Defense and Altered Peripheral Granulocyte Homeostasis in Mice Lacking the Adhesion Class G Protein Receptor, CD97. Infect Immun. 2007 Mar; 75(3): 1144-53.
Wang T, Ward Y, Tian L, Lake R, Guedez L, Stetler-Stevenson WG, Kelly K. CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counter receptors on endothelial cells. Blood. 2005 Apr 1, 105(7): 2836-44.