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Nathanael David Olson (Fed)

Bioinformatician

Dr. Nathan Olson joined the NIST-Genome In A Bottle (GIAB) team as a bioinformatician in 2018. He contributes to the development of small and structural variant benchmarks sets and reference material characterization. His work focuses on data management helping to ensure GIAB data are publicly available according to FAIR principles. Additionally, he leads the development of bioinformatic pipelines and work processes, improving the computational reproducibility and transparency of the GIAB benchmark set development process. During the COVID-19 pandemic, Nathan performed the RNA and DNA sequence analysis for SARS-CoV-2 RNA Research Grade Test Material (RGTM 10169). Currently, Nathan is an associate editor for Frontiers in Genomics.

PROJECTS

Active

Past Projects

RESEARCH OPPORTUNITIES

NIST-NRC Postdoctoral Fellowship: 2-year fellowship at NIST, US citizens only, ~$72,000 salary plus benefits, relocation expenses included, application deadlines are Feb. 1 and Aug. 1, requires 10-page research proposal, contact me if interested in writing a proposal on a bioinformatics genomics research project. We have opportunities posted for metrology in Cancer Genomics, Diploid Assembly, Epigenomics and Transcriptomics, Biological Data Science/Machine Learning, and Precision Medicine.

For additional job opportunities in genome bioinformatics, including for non-US citizens, contact me at my email address in the panel to the right.

PUBLICATIONS

ORCID - https://orcid.org/0000-0003-2585-3037
Google Scholar - https://scholar.google.com/citations?user=r7JrjGUAAAAJ
Loop profile - https://loop.frontiersin.org/people/200612/overview

Awards

Department of Commerce Silver Medal Award (2022)
Department of Commerce Gold Medal Award (2021)
Department of Commerce Gold Medal Award (2020)
Department of Commerce Gold Medal Award (2020)
Young Investigators in Analytical and Bioanalytical Science, Analytical and Bioanalytical Science (2016)
University of Maryland College Park University and Dean’s Fellowship (2015)
Accolade for Science Data Management and Capabilities, NIST Material Measurement Laboratory (2015)
University of Hawai‘i Hilo Volcan Outstanding Scholar Award. (2008)
Undergraduate Research Fellow, American Society of Microbiology (2007)

Publications

Small variant benchmark from a complete assembly of X and Y chromosomes

Author(s)
Justin Wagner, Nathanael Olson, Jennifer McDaniel, Lindsay Harris, Chunlin Xiao, Fritz Sedlazeck, Kishwar Shafin, Andrew Carroll, Justin Zook
The sex chromosomes contain complex, important genes impacting medical phenotypes, but differ from the autosomes in their ploidy and large repetitive regions

Data and Software Publications

Challenging Medically-Relevant Genes Benchmark Set

Author(s)
Justin Wagner, Nathan D Olson, Jennifer McDaniel, Justin M Zook
CMRG v1.00 of a small variant benchmark and structural variant benchmark focused on 273 challenging medically relevant genes for the Genome in a Bottle (GIAB) sample HG002 (aka Ashkenazi son). These
Created April 7, 2019, Updated February 22, 2023
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