Nathanael David Olson

Publications

High-coverage, long-read sequencing of Chinese trio reference samples

June 14, 2019

Author(s):

Justin M. Zook, Nathanael D. Olson, Marc L. Salit, Aaron Wenger, Chunlin Xiao, Robert Sebra

Genome In a Bottle (GIAB) is a consortium hosted by the National Institute of Standards and Technology whose primary objective is the development and...

An open resource for accurately benchmarking small variant and reference calls

April 01, 2019

Author(s):

Justin M. Zook, Jennifer H. McDaniel, Marc L. Salit, Nathanael D. Olson, Justin M. Wagner

Benchmark small variant calls are required for developing, optimizing and assessing the performance of sequencing and bioinformatics methods. Here, as part of...

Impact of conventional wastewater treatment and reuse site practices on the bacterial community structure of reclaimed water

October 15, 2018

Author(s):

Prachi Kulkarni, Nathanael D. Olson, Joseph N. Paulson, Mihai Pop, Cynthia Maddox, Emma Claye, Rachel E. Rosenberg Goldstein, Manan Sharma, Amy R. Sapkota

Reclaimed water use continues to expand across the United States, from areas that have access to advanced, potable-level treated reclaimed water, to areas that...

Using metagenomic methods to detect organismal contaminants in microbial materials.

September 12, 2017

Author(s):

Nathanael D. Olson, Justin M. Zook, Jayne B. Morrow, Nancy J. Lin

High sensitivity methods as next generation sequencing and PCR are adversely impacted by organismal and DNA contaminants. Current methods for detecting...

Metagenomic assembly through the lens of validation: a review of recent advances in assessing and improving the quality of genes and genomes assembled from metagenomes.

August 07, 2017

Author(s):

Nathanael D. Olson, Chris M. Hill, Vistoria Cepeda-Espinoza, Jay Ghurye, Sergey Koren, Todd J. Treangen, Mihai Pop

Metagenomic samples are snapshots of complex ecosystems at work. These samples often involve hundreds of bacteria from known and unknown species, contain...