NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.
Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.
An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Different genomic technologies have been applied to cell line authentication, but only one method (short tandem repeat profiling) has been the subject of a comprehensive standard (ASN-0002). Here we discuss the power of this document, and why standards such as this are so critical for establishing the consensus technical criteria and practices that can enable progress in the fields of research that use cell lines. We also examine other methods that could be used for authentication, and discuss how a combination of methods could be used in a holistic fashion to assess various critical aspects of the quality of cell lines.
Almeida, J.
, Cole, K.
and Plant, A.
(2016),
Standards for cell line authentication and beyond, Plos Biology, [online], https://doi.org/10.1371/journal.pbio.1002476, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=920021
(Accessed October 8, 2025)