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Zhiyong He (Fed)

Biologist

Research interests

  1. Developing reference materials for cancer biomarkers, such as methylated genomic DNA and cfDNA for DNA methylation measurements.
  2. Developing Lentiviral vector (LVV) copy number reference materials, developing LVV titer measurement methods and LVV genome integrity measurement methhods.
  3. Developing immune-therapy CAR-T reference materials and protocols for measurements.
  4. Developing tumor and matched normal cell lines.

Publications

Development, characterization, and inter-laboratory validation of methylated human cell free DNA candidate reference materials

Author(s)
Zhiyong He, Hua-Jun He, Kenneth Cole, Yves Konigshofer, Russell Garlick, Jayanthi Ramprakash, Matthew Young, Eric Hall, Adam Corner, Michelle Clarissa, Jocelyn Wright, Victoria Cannon, Ming Yu, William Grady, Cecilia Yeung, Zachary Heimer, Zhili Wang, ShiPing Zou, Shidong Jia, Fang Liu, Giancarlo Bonora, Karol Bomsztyk, Daniel Mar
Aberrant DNA methylation biomarkers have demonstrated potential for early cancer detection, multicancer detection, and determining the tissue of origin. Due to...

Gene Copy Number Dictates Extracellular Vesicle Cargo

Author(s)
Sumeet Poudel, Zhiyong He, Jerilyn Izac, Lili Wang
Extracellular vesicles (EVs) are membrane-surrounded vesicles that carry heterogeneous cellular components, including proteins, nucleic acids, lipids, and...
Created February 18, 2021, Updated February 27, 2023
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