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NIST on a Chip

NIST on a Chip Patents

Gravity Flow Micro-Physiological Article And Determining A Physiological Response To A Drug

NIST Inventors

Mandy B. Esch, PhD

The invention is a microphysiological system that is an open microfluidic multi-organ cell culture system. Fluidic flow is achieved with via gravity, and physiological fluid residence times are achieved by operating the device with a rotating platform at a particular speed. The device only contains

Dynamic Force Contactor, Providing a Dynamic Force, and Calibrating a Force Sensor to be Traceable to the International System of Units

NIST Inventors

Akobuije Chijioke

A dynamic force contactor includes: a magnet that provides a magnetic field; an electrical conductor that provides an electric field perpendicular to the magnetic field, the electric field from the electrical conductor in combination with the magnetic field from the magnet providing a Lorentzian

Optical Temperature Sensor

NIST Inventors

Zeeshan Ahmed , Steve Semancik , Jacob Taylor and Gregory F. Strouse

A thermometer includes a substrate; an optical resonator disposed on the substrate and including an optical resonance, the optical resonator being configured to receive a resonant frequency corresponding to the optical resonance; and a waveguide disposed on the substrate proximate to the optical

Schematic of magnetometer/gyroscope shows layers with photodetectors on top and laser at bottom.

Compact Atomic Magnetometer and Gyroscope

NIST Inventors

John Kitching and Elizabeth Donley

The NIST Compact Atomic Magnetometer is based on a diverging (or converging) beam of light that passes through an alkali atom vapor cell and that contains a distribution of beam propagation vectors. The existence of more than one propagation direction permits longitudinal optical pumping of the

Optofluidic Flow Meter

NIST Inventors

Zeeshan Ahmed and Gregory A Cooksey

Optofluidics is the marriage of microfluidics and optical technology. The NIST Optical Flow Meter (US Patent 10,151,681) provides an on-chip assessment of flow and heat transfer, resulting in vast improvements in fluid metrology and advances in biological sensing.

Illustrates a microfluidic device including an alkali vapor cell and a microfluidic channel where the alkali vapor cell is illuminated by a laser beam and a segmented photodiode detects the laser beam after its transmission through the alkali vapor cell according to an embodiment of the present invention. Item 100 is the microchip; item 102 is the laser; item 104 is the fluidic channel; item 106 is the alkali vapor cell; and item 108 is the segmented photodiode.

Integrated Microchip Incorporating Atomic Magnetometer and Microfluidic Channel for NMR and MRI

NIST Inventors

John Kitching

Our invention uses very small alkali vapor cells with sensitivity for detecting very small DC magnetic fields produced by a small sample of fluid without cryo-cooling. It improves on existing remote detection of low-field NMR and MRI: The invention uses a very small atomic magnetometer with

Detection of J-Coupling Using Atomic Magnetometer

NIST Inventors

John Kitching

Nuclear magnetic resonance (NMR) is a powerful tool for determining molecular structure and properties. Our invention provides for the direct detection of hetero- and homonuclear scalar coupling in a zero-field or low-field environment using an optical atomic magnetometer. It provides NMR without

Optical meter 1 includes ref ector 4 disposed force member 2. Ref ector 4 is conf gured to receive radiation and to communicate a pressure of the radiation to force member 2. Ref ector 4 includes substrate 5 and ref ective surface 8. Force member 2 is conf gured to be displaced in response to receiving the force comprising the pressure, and optical meter 1 is conf gured to measure a power of the radiation, an energy of the radiation, or a combination thereof based on the pressure.

Optical Meter and Use of Same

NIST Inventors

John H. Lehman and Paul A. Williams

With this technology, high-power laser beams from 1-kilowatt (kW) up to 140 kW (and beyond) can be measured accurately using optical radiation pressure. By shining a laser beam on a reflective surface and then measuring how much the surface moves in response to the light’s pressure, researchers can

A disk-shaped device is smaller than the half-dollar coin underneath it.

Smart Mirror

NIST Inventors

Alexandra (Aly) Artusio-Glimpse , John H. Lehman , Michelle Stephens , Nathan A Tomlin and Paul A. Williams

Radiation pressure is a force that results when light reflects from a mirror. By measuring the force on a mirror, the power in a laser beam can be assessed. We have invented a miniaturized mirrored force sensor that combines several key elements to make a sensor that is smaller, faster, more

Clockwise from upper left: bolometer for optical fiber power measurement operates at 4K, bolometer for space-based measurement of solar spectral irradiance, operates at room temperature; bolometer for continuous wave, visible/near infrared laser power measurement, operates at room temperature; bolometer for fast far infrared power calibration, operates at 4K.

NIST Radiometer

NIST Inventors

John H. Lehman and Nathan A Tomlin

This advanced radiometer is composed of a substrate, a radiation absorber placed on the substrate to absorb radiation, a thermal component placed on the substrate to change electrical resistance in response to a change in temperature of the radiometer, and a thermal link to connect the radiometer to

Created July 1, 2020, Updated March 19, 2021

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