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Reference Materials

NIST is actively develop new biological reference materials for various biotechnology and biomanufacturing applications. Please see below for ongoing interlaboratory studies.

BIOMATERIALS

CELLS

FLOW CYTOMETRY

  • SRM 1932 - Fluorescein Solution
  • SRM 1934 – Fluorescent Dyes for Quantitative Flow Cytometry

Fluorescence & absorbance spectrometry

NANO-ENVIRONMENTAL HEALTH AND SAFETY

  •  RM 8027 - 2 nm Silicon Nanocrystal

NUCLEIC ACID/GENOMIC BIOMARKER

  • SRM 2373 - Genomic DNA Standards for HER2 Measurements
  • SRM 8366 - EGFR and MET Gene Copy Number Standards for Cancer Measurements 
  • Genome in a Bottle human genome RMs:
    RM 8391 - Human DNA for Whole-Genome Variant Assessment (Son of Eastern European Ashkenazim Jewish Ancestry)
    RM 8392 - Human DNA for Whole-Genome Variant Assessment (Trio of Eastern European Ashkenazim Jewish Ancestry)
    RM 8393 - Human DNA for Whole-Genome Variant Assessment (Son of Chinese Ancestry)
    RM 8398 - Human DNA for Whole-Genome Variant Assessment (Daughter of Utah/European Ancestry)
  • RM 8375 - Microbial Genomic DNA Standards for Sequencing Performance Assessment
  • SRM 2374 - DNA Sequence Library for External RNA Controls 
  • Additional NIST DNA Reference Materials
    Created April 3, 2016, Updated February 6, 2023