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Standard Guides and Protocols
BBD staff actively participate in and lead the development of Documentary Standards through standards developing organizations (SDOs). NIST administers and chairs the US Technical Advisory Group (TAG) to ISO/TC 276: Biotechnology.
We engage with the following standards organizations and committees in the biosciences and health sectors.
- ISO/TC 229: Nanotechnology
- ISO/TC 276: Biotechnology
- ISO/TC 106: Dentistry
- ASTM F04
- ASTM E54: Homeland Security
- PDA: Cell Transportation
- CLSI: Clinical Standards
- ATCC: Cell Line Authentication
We also coordinate standards development with professional societies and other organizations such as USP, ISCT, ASGCT, AABB, and FACTS.
The below content is for information only; it does not imply endorsement by NIST.
biotechnology
BIOTHREAT DETECTION
- ASTM E2458-17 Standard Practices for Bulk Sample Collection and Swab Sample Collection of Visible Powders Suspected of Being Biological Agents and Toxins from Nonporous Surfaces
- ASTM E2770-17 Standard Guide for Operational Guidelines for Initial Response to Suspected Biological Agents and Toxins
- ASTM E3095-17 Standard Guide for Surrogate Materials for Field Evaluation of Nucleic Acid-Based On-Site Biological Assessment Technologies
Regenerative Medicine
- ASTM F2791 - Assessment of Surface Texture of Non-Porous Biomaterials in Two Dimensions,
- F2997-13 Standard Practice for Quantification of Calcium Deposits in Osteogenic Culture of Progenitor Cells Using Fluorescent Image Analysis
- F3088-14 Standard Test Method for Use of a Centrifugation Method to Quantify/Study Cell-Material Adhesive Interactions
- F3106-14 Standard Guide for in vitro Osteoblast Differentiation Assays
- F2603-06(2012) Standard Guide for Interpreting Images of Polymeric Tissue Scaffolds
- F2952-14 Standard Guide for Determining the Mean Darcy Permeability Coefficient for a Porous Tissue Scaffold
- F3089-14 Standard Guide for Characterization and Standardization of Polymerizable Collagen-Based Products and Associated Collagen-Cell Interactions
- ASTM Working Group WK65476 to develop “Standard Guide for Characterizing Fiber-Based Constructs for Tissue Engineered Medical Products” (in preparation)
Nano-Environmental Health and Safety
- Guidance Document on Aquatic (and Sediment) Toxicological Testing of Nanomaterials, OECD (under development)
- Control experiments to avoid artifacts and misinterpretations in nanoecotoxicology testing. NIST Special Publication 1200-11
- Reconstitution of 2 nm diameter Silicon Nanoparticles (RM8027) into aqueous solvents. NIST Special Publication 1200-12
- Measurement of silver nanoparticle dissolution in complex biological and environmental matrices using UV/visible absorbance measurements. NIST Special Publication 1200-13
- Reliable preparation of nanoparticle agglomerates of different sizes in cell culture media, NIST Special Publication 1200-14
Flow Cytometry
Microscopy
- Guide for Using Fluorescence Microscopy to Quantify the Spread Area of Fixed Cells, ASTM F2998-14
- ASTM F3294 - 18 Standard Guide for Performing Quantitative Fluorescence Intensity Measurements in Cell-based Assays with Widefield Epifluorescence Microscopy
- An automated protocol for performance benchmarking a widefield fluorescence microscope