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Displaying 101 - 125 of 134

Premixed Rapid-Setting Calcium Phosphate Composites for Bone Repair

January 1, 2005
Author(s)
Lisa E. Carey, Hockin D. Xu, Carl Simon Jr., Shozo Takagi, Laurence C. Chow
Abstract (A-2000 character or less factual summary of most significant information. If document includes a significant bibliography or literature survey, cite it here. Spell out acronyms on first reference.) Although calcium phosphate cement (CPC) is

High-Throughput Method for Determining Modulus of Polymer Blends

December 1, 2004
Author(s)
Carl G. Simon Jr., Naomi Eidelman, Y N. Deng, N Washburn
Polymer blending is commonly used to create materials with improved mechanical properties, but the resulting material properties can have a complex dependence on composition and processing conditions (Paul, 1986). In order to accelerate polymer-blend

Combinatorial Methods for Rapid Screening of Biomaterials

October 1, 2004
Author(s)
Carl G. Simon Jr., N Washburn, S B. Kennedy, Naomi Eidelman, Y N. Deng, Eric J. Amis
Current methods for biomaterials development involve one-specimen-at-a-time characterization which is costly and time-consuming. Combinatorial and high-throughput methods hold the potential to enhance research and development in any field of scientific

Cell Seeding into Calcium Phosphate Cement

March 1, 2004
Author(s)
Carl Simon Jr., William F. Guthrie, Francis W. Wang
We have sought to improve calcium phosphate cement by developing a method for seeding bone cells into the cement. Calcium phosphate cement (CPC) is a dry white powder of calcium phosphate salts that when mixed with water will react to form microcrystalline

Dynamical Adhesion Force of Cells on Biomaterial Substrates

February 1, 2004
Author(s)
Y N. Deng, Carl Simon Jr., P M. McGuiggan, Sheldon M. Wiederhorn, Brian R. Lawn
The adhesion of cells to synthetic biomaterial implant surfaces is an essential step for tissue growth in bone repair. Such adhesion can mandate whether the tissue will accept or reject the implanted biomaterials. In this study, the adhesion forces between

Combinatorial Screening of Cell-Material Interactions

January 1, 2004
Author(s)
N. R. Washburn, Carl Simon Jr., Michael Weir, L A. Bailey, S B. Kennedy, Eric J. Amis
Tissue engineering applications involve developing materials to guide cellular response in the repair of missing or damaged tissue. We have been developing combinatorial methods for characterizing the functional dependence of cellular responses on material

Imaging Cells on Polymer Spherulites

January 1, 2004
Author(s)
Carl G. Simon Jr.
Polymers are one of the many materials used to fabricate tissue engineered medical products (Ratner et al., 1996). Polymer processing methods, such as how monomers are converted to polymers or how polymers are formed into products, can drastically affect

High-Throughput Investigation of Cell Proliferation on Crystalline Polymers

April 1, 2003
Author(s)
N. R. Washburn, S B. Kennedy, Carl Simon Jr., K Yamada, Eric J. Amis
The results of our investigation of cell proliferation on crystalline polymers will be presented. The goal of the research is to investigate how cells respond to nanometer scale roughness, and crystallizing poly(L-lactic acid) (PLLA) was a convenient
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