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Displaying 126 - 135 of 135

High-Throughput Investigation of Cell Proliferation on Crystalline Polymers

April 1, 2003
Author(s)
N. R. Washburn, S B. Kennedy, Carl Simon Jr., K Yamada, Eric J. Amis
The results of our investigation of cell proliferation on crystalline polymers will be presented. The goal of the research is to investigate how cells respond to nanometer scale roughness, and crystallizing poly(L-lactic acid) (PLLA) was a convenient

Preliminary Report on the Biocompatibility of a Moldable, Resorbable, Composite Bone Graft Consisting of Calcium Phosphate Cement and Poly (Lactide-Co-Glycolide) Microspheres

May 1, 2002
Author(s)
Carl Simon Jr., C A. Khatri, Scott Wight, Francis W. Wang
We have assessed the biocompatibility of a new composite bone graft consisting of calcium phosphate cement (CPC) and poly(lactide-co-glycolide) (PLGA) microspheres (175-350 ?m) using cell culture techniques. CPC powder is mixed with PLGA microspheres and

Co-Extrusion of Biocompatible Polymers for Scaffolds With Co-Continuous Morphology

April 1, 2002
Author(s)
N. R. Washburn, Carl Simon Jr., Alessandro Tona, H M. Elgendy, Alamgir Karim, Eric J. Amis
A methodology for the preparation of porous scaffolds for tissue engineering using co-extrusion is presented. Poly(espilon-caprolactone) is blended with poly(ethylene oxide) in a twin-screw extruder to form a two-phase material with micron-sized domains

Structured Polymeric Templates: Combinatorial Probes for Cellular Response

January 1, 2001
Author(s)
A Sehgal, Jack F. Douglas, Francis W. Wang, Carl G. Simon Jr., Alamgir Karim, Eric J. Amis
Novel high-throughput gradient methods have been developed to generate a range of surface structures by dewetting and phase separation on chemically patterned substrates. The research is motivated by an increasing awareness in the biomedical industry and
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