Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Molecular and BioPhotonics Group

Molecular and BioPhotonics research lies at the intersection of physics, chemistry, engineering, and life sciences. The development of photonic techniques, which use light to detect, quantify, and image molecules and biomolecules, are used to establish the optical measurement science, modeling, and simulation tools critical to realizing many applications in medicine, energy, and the environment.

The Molecular and BioPhotonics group research efforts focus on the development of the following:

  • New photonic spectroscopic and imaging techniques for enhanced detection of molecules and biomolecules;
  • Measurement standards for improving manufacturing quality and promoting acceptance of optical medical imaging technologies; and
  • The application of photonics techniques to real world problems.

Projects and Programs

Nano-biophotonics for molecular imaging

Biophotonics is at the intersection of photonics and biology where light is used to image, detect, and manipulate biological materials. This project addresses



JB95 Spectral fitting program

A graphical user interface program, JB95, based on a Windows 95 © API platform has been written in the C programming language to aid in the analysis of complex

Tools and Instruments

Continuous-wave terahertz spectrometer

The continuous-wave terahertz spectrometer makes use of two near-infrared lasers. The first laser is a fixed-frequency cw ring Ti:Saph laser operating near 840

Nonlinear Optical Spectroscopy

Vibrationally-Resonant Sum Frequency Spectroscopy (VR-SFS): A nonlinear vibrational spectroscopy in which two colors of light, one in the visible and one in the



Photoacoustic Photon Meter And Process For Measuring Photon Fluence

NIST Inventors
Kimberly A. Briggman , Chris Yung , Jeeseong C. Hwang and John H. Lehman
A photoacoustic photon meter includes: a photoacoustic generative array including carbon nanotubes disposed in a photoacoustic generating pattern, such that the carbon nanotubes: receive photons comprising optical energy, and produce thermal energy from the optical energy; and a superstratum

Optical Phantom for Producing a Time-Resolved Diffuse Reflectance Spectrum

NIST Inventors
Jeeseong C. Hwang
An optical phantom produces a time-resolved diffuse reflectance spectrum and includes: a light source; a spatial light modulator; and an optical delay line including optical fibers of different length that produce different time-of-flight distributions, such that different time-of-flight


Group Leader

Postal address: Molecular and Biophotonics Group, NIST - 687.05, 325 Broadway, Boulder, CO 80305