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Optical Phantom for Producing a Time-Resolved Diffuse Reflectance Spectrum

Patent Number: 10,408,741


An optical phantom produces a time-resolved diffuse reflectance spectrum and includes: a light source; a spatial light modulator; and an optical delay line including optical fibers of different length that produce different time-of-flight distributions, such that different time-of-flight distributions are combined and produce phantom light having the time-resolved diffuse reflectance spectrum.

Patent Description

Physikalisch-Technische Bundesanstalt (PTB) and NIST jointly developed a concept for a waveform synthesizer which can generate a controlled waveform with several picosecond (ps) time resolution.  In a light-diffusing material, characteristics of the time-of-flight distribution (e.g. temporal broadening and intensity attenuation) of a transmitted light pulse are associated with tissue optical properties such as scattering and absorption.  The synthesizer can generate waveforms mimicking time-of-flight distributions attributed to a unique physiological condition of specific tissue such as blood oxygenation in cerebral tissue, enabling cerebral tissue oximetry standards.  A broad range of applications is expected to fulfill the needs for tailoring the arbitrary shape of light pulses.


No measurements to realize the proposed method have been performed. A broad range of applications is expected where there is a need for tailoring arbitrary shape of (picosecond to nanosecond) light pulses.  The technique may advance the quality control in manufacturing materials with desired optical properties.

Created March 12, 2020, Updated April 11, 2024