An optical phantom produces a time-resolved diffuse reflectance spectrum and includes: a light source; a spatial light modulator; and an optical delay line including optical fibers of different length that produce different time-of-flight distributions, such that different time-of-flight distributions are combined and produce phantom light having the time-resolved diffuse reflectance spectrum.
Physikalisch-Technische Bundesanstalt (PTB) and NIST jointly developed a concept for a waveform synthesizer which can generate a controlled waveform with several picosecond (ps) time resolution. In a light-diffusing material, characteristics of the time-of-flight distribution (e.g. temporal broadening and intensity attenuation) of a transmitted light pulse are associated with tissue optical properties such as scattering and absorption. The synthesizer can generate waveforms mimicking time-of-flight distributions attributed to a unique physiological condition of specific tissue such as blood oxygenation in cerebral tissue, enabling cerebral tissue oximetry standards. A broad range of applications is expected to fulfill the needs for tailoring the arbitrary shape of light pulses.
No measurements to realize the proposed method have been performed. A broad range of applications is expected where there is a need for tailoring arbitrary shape of (picosecond to nanosecond) light pulses. The technique may advance the quality control in manufacturing materials with desired optical properties.