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Search Publications by Wyatt N. Vreeland

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Displaying 1 - 25 of 38

Microfluidic Synthesis of Nano-Liposomal Anesthetics

Wyatt N. Vreeland, Renee R. Hood, Eric Kendall, Mariana Junqueira, Julia Finkel, Don L. DeVoe
Topical anesthesia has the ability to provide painless application of pain management medications for minor procedures such as venipuncture, particularly in the

Radiation-Induced Synthesis of Poly(vinylpyrrolidone) Nanogel

Jung-Chul An, Alia Weaver, Byungnam Kim, Aaron Barkatt, Dianne L. Poster, Wyatt N. Vreeland, Joseph Silverman, Mohamad Al-Sheikhly
Studies of the radiation-induced synthesis of poly(vinylpyrrolidone) (PVP) nanogels, intended to provide a basis for obtaining intra-molecular cross-linked

Microfluidic Mixing and the Formation of Nanoscale Lipid Vesicles

Andreas Jahn, Samuel M. Stavis, Jennifer S. Hong, Wyatt N. Vreeland, Don L. DeVoe, Michael Gaitan
We investigate the formation of unilamellar lipid vesicles (liposomes) with diameters of tens of nanometers by microfluidic hydrodynamic focusing (MHF). Our

Accurate optical analysis of single molecule entrapment in nanoscale vesicles

Joseph E. Reiner, Andreas Jahn, Samuel M. Stavis, Michael J. Culbertson, Wyatt N. Vreeland, Daniel L. Burden, Jon C. Geist, Michael Gaitan
We present a non-destructive method to characterize low analyte concentrations in nanometer scale lipid vesicle formulations. Our method is based on the

Magnetic connectors for microfluidic applications

Francisco J. Atencia, Gregory A. Cooksey, Andreas Jahn, Justin M. Zook, Wyatt N. Vreeland, Laurie E. Locascio
We present a new type of connector based on a simple idea: using a ring magnet on one side of the microfluidic chip and a disc magnet on the other side to

Contactless Differential Conductivity Detection

Gordon A. Shaw, David J. Ross, Steven E. Fick, Wyatt N. Vreeland
We propose a new technique, contactless differential conductivity detection (CDCD,) to improve the detection limit of contactless conductivity detection for

Microfluidic DNA Analysis Systems for Forensic Applications

Michael Gaitan, Jayna J. Shah, Darwin R. Reyes-Hernandez, Pierre-Alain Auroux, Jon C. Geist, Laurie E. Locascio, Wyatt N. Vreeland, David J. Ross, Peter M. Vallone, Paul Smith, Nicole Morgan, Tom Pohida, John Kakareka, Annelise Barron
This report summarizes the NIST effort on microfluidic DNA analysis systems for forensic applications sponsored by the National Institute of Justice. Currently

Liposome-Templated Supramolecular Assembly of Responsive Alginate Nanogels

Jennifer S. Hong, Wyatt N. Vreeland, Silvia H. De Paoli Lacerda, Laurie E. Locascio, Michael Gaitan, Srinivasa R. Raghavan
Nanosized gel particles (nanogels) are of interest for a variety of applications, including controlled release of drugs and single-molecule encapsulation. Here

Preparation of Nanoparticles by Continuous-Flow Microfluidics

Andreas Jahn, Joseph E. Reiner, Wyatt N. Vreeland, Don DeVoe, Laurie E. Locascio, Michael Gaitan
We review a variety of micro- and nanoparticle formulations produced with microfluidic methods. A diverse variety of approaches to generate micro-scale and nano

Microfluidic Directed Formation of Liposomes of Controlled Size

Andreas Jahn, Wyatt N. Vreeland, Don DeVoe, Laurie E. Locascio, Michael Gaitan
A new method to tailor liposome size and size distribution in a microfluidic format is presented. Liposomes are spherical structures formed from lipid bilayers