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Chemistry

Projects/Programs

Keyword

Organizational Unit

International Comparisons for Chemical Measurements

Ongoing

Because of NIST's role as the National Metrology Institute (NMI) in the U.S., the Chemical Sciences Division's measurement capabilities must be benchmarked

Figure with the word “isotope” and related icons superimposed on a photograph of a man pointing to the figure.

Isotope Metrology

Ongoing

Stable and radioactive isotope analysis is an important interdisciplinary tool used by numerous scientists. Therefore, achieving reliable metrology and

Label-free imaging of cells and their extracellular matrix by SPR imaging

Ongoing

Low Temperature Regenerator and Pulse Tube Losses

Ongoing

The Cryogenic Technologies Project has been funded by ONR since FY2005 to measure and model the losses in 4 K regenerators and pulse tubes. These thermal

Machine Learning Fluid Equations of State

Ongoing

By using machine learning approaches, we seek to elucidate underlying universal characteristics of fluids and fluid mixtures that enable property prediction

Machine Learning to Predict Multicomponent Colloidal Crystals

Ongoing

We use machine learning and other computational techniques to predict the self-assembly characteristics of multicomponent colloidal materials. This is a

Macromolecular Architectures

Ongoing

There is always a degree of uncertainty surrounding measurements of polymeric materials, especially complex mixtures with varying distributions in chemistry

Magnetic Sector Secondary Ion Mass Spectrometry

Ongoing

Magnetic sector secondary ion mass spectrometry (SIMS) generates isotopic and elemental information from solid surfaces with depth profiling capabilities to

Materials Informatics

Ongoing

The Materials Genome Initiative will create a new era of materials innovation that will serve as a foundation for strengthening domestic industries in these

Measuring Intermolecular Interactions with Electro-Acoustic Spectroscopy

Ongoing

NIST’s Material Measurement Laboratory and Communications Technology Laboratory are developing a new spectroscopy for intermolecular interactions. The team is

Schematic of approach to clean water membranes

Membranes for Clean Water

Completed

This project provides measurement solutions that probe the surface and internal structure of polymer membranes used in water purification, and correlate that

Method Assessment for Non-Targeted Analyses (MANTA) Program

Ongoing

The MANTA Program is an ongoing collaboration with laboratories to increase the comparability and reproducibility of their results using non-targeted analysis

Methods and Measurements of Nanoparticle Accumulation and Distribution in Organisms

Completed

Given the substantial differences between nanoparticles (NPs) and typical organic and inorganic environmental contaminants, new experimental methods and

Methods and Measurements of Nanoparticle Distribution in the Natural Environment

Ongoing

Given the substantial differences between nanoparticles (NPs) and typical organic and inorganic environmental contaminants, new methods and analytical

Metrologies for Protein Structure, Function, and Modeling

Ongoing

NIST researchers in the Macromolecular Structure and Function Group are involved in a joint research program with scientists from the University of Maryland

pH Metrology

Ongoing

The pH metrology program supports traceability for pH measurements. This traceability rests on primary pH measurements in an ideal electrochemical cell (Harned

Metrology and Standards for Canine Olfactory Detection of Explosives

As part of a multi-year interagency agreement between the Office of Standards of the Department of Homeland Security and NIST, NIST is developing measurement

Microcryocooler for Terahertz Detectors

Ongoing

NIST and the University of Colorado have been funded since April, 2006, by DARPA to develop a microcryocooler with a volume less than about 4 cm 3 to cool a

Micronutrients Measurement Quality Assurance Program (MMQAP)

Completed

The Micronutrients Measurement Quality Assurance Program (MMQAP) was initiated in 1984 by the National Cancer Institute Division of Cancer Prevention and

Microresonators for inductive-detection electron paramagnetic resonance spectroscopy of volume-limited samples

Ongoing

Planar microresonators are fabricated in the NIST Nanofab, tested in our laboratory, and incorporated into a commercial 9 GHz or NIST-built 34 GHz electron

A stainless steel micro tensile specimen in a silicon frame.

Microsystems for Harsh Environment Testing

Completed

Our goal is to develop and demonstrate a MEMS-based methodology for evaluating time-dependent mechanical properties of materials that undergo exposure to

Multidimensional Chromatography

Ongoing

Both comprehensive two-dimensional gas chromatography (GCxGC) and comprehensive two-dimensional liquid chromatography (LCxLC) have emerged as powerful tools

Multiplexed "Detectorless" Electrophoresis

Ongoing

The ability to acquire large amounts of high quality data very rapidly is increasingly important for progress in the biological sciences. Capillary

PTIR combines the spatial resolution of AFM with the specificity of absorption spectroscopy

Nano-Chemical Imaging and -Spectroscopy (IR, nIR, VIS)

Ongoing

Conventional techniques for analyzing chemical composition, such as infrared (IR) microscopy often miss critically important nanoscale details. To overcome this

Nanoscale Thermal Properties

Completed

Our goal is to develop measurement techniques to characterize the changes in thermal transport and thermal transition temperatures in polymeric and hybrid

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