Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Projects/Programs

Displaying 501 - 525 of 569

Structural Metrology of Advanced Manufacturing Processes

Ongoing
Understanding material structures in advanced manufacturing is crucial because it enables precise control over material properties, leading to improved performance, efficiency, and cost-effectiveness in production processes. However, this understanding poses many challenges, such as the

Structure-Property Links in Deformation of Materials

Ongoing
The fundamental physics of the deformation process in metals is controlled by crystal plasticity, a type of non-recoverable strain whose evolution depends on the deformation history of the material (as in all plastic processes), and the relative orientation of the applied load and the crystalline

Structure-Property Relationships for High-Strength Materials

Ongoing
The body-armor community generally bases armor design on empirical models that do not directly relate molecular properties to performance. Aramid, aramid copolymers, and polyethylene fibers are highly oriented, anisotropic fibers that require specialized characterization techniques. In addition

Study of Microheterogeneity in Solid Reference Materials

Ongoing
Presently there are a variety of analytical techniques that are served by few or no reference materials due to the small sample sizes they require. NIST currently certifies solid reference materials at or above the 100 mg mass level in most cases with no mention of the effect of using smaller sample

Sub-nanoscale electron microscopy of complex nanostructures

Ongoing
The properties of advance materials are becoming ever more reliant on the ability to manipulate their chemistry and structure at very fine length scales. For example, the relevant feature sizes in state-of-the-art transistors continue to decrease, even as the complexity of the architectures employed

Surface Desorption Ambient Mass Spectrometry

Ongoing
The Surface and Trace Chemical Analysis Group maintains a range of research avenues into the characterization, analysis, and optimization of various commercial and in-house developed surface desorption ion sources. These research avenues also aim to advance our fundamental understanding of the

Surrogate protein particle standards

Ongoing
Intended Impact This work will enable industry to obtain accurate, reproducible counts of protein particles, and to differentiate protein particles from other particle types, resulting in greater drug efficacy and safety. Objectives Create a polydisperse suspension of polymer particles that mimic

Synchrotron Resonant Scattering and Diffraction

Ongoing
The Resonant Scattering and Diffraction effort seeks to develop measurements that provide spatial correlations in chemical, electronic, and physical structure in advanced materials. Scattering technology is developed as part of the NIST BNL partnership at the National Synchrotron Light Source II in

Synchrotron X-ray Absorbance Spectroscopy

Ongoing
The Absorbance Spectroscopy effort seeks to develop measurements that provide details of the local chemical, electronic, and physical structure in advanced materials. Spectrometer technology is developed as part of the NIST BNL partnership at the National Synchrotron Light Source II in Upton, NY

Synchrotron X-ray Spectroscopic Imaging

Ongoing
Building off technologies and expertise developed in the Synchrotron X-ray Absorption Spectroscopy project, the Spectroscopic Imaging effort seeks to develop measurements that provide spatial mapping of the local chemical, electronic, and physical structure in advanced materials. Technology is

Synthesis and longevity of candidate direct air capture (DAC) materials

Ongoing
We have been working on the identification and development of repeatable synthesis techniques for DAC materials for the purposes of generating repeatable samples for evaluating DAC characterization techniques. We have initially focused on impregnated and grafted aminosilane-silica materials. We are

Synthetic Biology

Ongoing
New measurement methods and tools are required for biology to emerge fully as an enabling, practical platform for engineering. The Cellular Engineering Group works to provide a foundation of measurement assurance to support the control and rational design of biological function. Through state of the

U.S. TAG for ISO/TC276: Biotechnology

Ongoing
Get involved: Interested U.S. Stakeholders may participate in the US TAG at no cost. Membership provides access to all ISO/TC 276 and US TAG documents, including standards under development. Please click here to join. Contribute to standards development: Please click here to review, submit comment

Tandem Mass Spectral Library

Ongoing
Intended Impact Modern mass spectrometers commonly generate ions by electrospray mass spectrometry which are separated and then fragmented by collisional dissociation. This process yields fragment ion ‘fingerprints’ (or mass spectra) that are widely used to identify the individual components in a

Targeting Membrane Proteins

Ongoing
Membrane proteins constitute approximately 30% of all cellular proteins. Nevertheless, this group of proteins is traditionally understudied due to limitations of the available analytical tools. Given the importance of membrane proteins in the various cellular processes and their potential as drug

Teaching Liquid State Theory to an Artificial Neural Network (ANN)

Ongoing
Scientific questions: Can an ANN allow us to predict the structure of fluids that are impossible to predict numerically via liquid-state theory? Can we learn something about liquid-state theory itself by the nature of the trained ANN? What features do the hidden layers capture?

Templated Assembly of Block Copolymer Films

Completed
Viable nanomanufacturing of templated block copolymers will require a capability to control orientation and line edge roughness of trillions of structures to within a single nanometer, however there are no existing platforms that meet this need. We are developing small angle x-ray and neutron

Tension-Compression Testing

Ongoing
The inability to reliably predict the mechanical behavior of new automotive alloys during forming has generated strong demand for more advanced constitutive relationships and property data necessary to calibrate them. There is a particular need for models that incorporate combined kinematic and

Theoretical Mass Spectrometry

Ongoing
No Description Intended Impact Unknown compounds will be identified more reliably. Quality control for the NIST Mass Spectrometry Database will be enhanced. Goals Develop software tools for predicting microcanonical branching fractions automatically. This is currently too laborious and too technical
Was this page helpful?