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Office of the Director

Projects/Programs

Displaying 1026 - 1050 of 1614

NIST Genome Editing Consortium: Working Group 1 - Specificity Measurements

Ongoing
Genome editing technologies are able to produce DNA sequence changes of a variety of sizes and at a variety of frequencies in a population of edited cells. Having increased confidence in reliably detecting the sequences generated by a genome editing process was a need area identified. Project 1...

NIST Genome Editing Consortium: Working Group 2 - Data & Metadata

Ongoing
Develop a metadata schema for genome editing experiments Develop a way of curating and entry that is low burden for user Release control data with linked metadata PROGRESS Phase1 metadata entries and templates completed In process of compiling and testing use cases, user interfaces, and...

NIST Genome Editing Lexicon

Ongoing
The definitions are worded with the intention that additional context may be added with supplementary language when they are used. It is also recognized that genome editing is a rapidly evolving biotechnology and additional terms and definitions will be needed as genome editing technologies mature...

NIST Genome Editing Program

Ongoing
For genome editing systems to reach their full potential in research and commercial products, new measurement tools, capabilities, and standards must be developed to efficiently implement and assess the performance of these editing technologies, as well as to evaluate the utility of resulting...
HER2 SRM Unit and Individual Components

NIST HER2 Genomic DNA Standard Reference Material, SRM® 2373

Completed
The amplification of the gene for HER2 occurs in approximately 20 to 25% of breast cancers. The accurate measurement of this biomarker is important for the proper treatment with anti-HER2 therapeutics. Clinical laboratories are beginning to utilize accurate and sensitive diagnostic tests based on...
NIST Industrial Wireless Systems 5G Testbed

NIST Industrial Wireless 5G Testbed

Ongoing
The NIST 5G Industrial Wireless Testbed project aims to revolutionize industrial connectivity by deploying and evaluating the capabilities of 5 th generation (5G) wireless technology within an industrial setting. This initiative responds to the emerging demand for ultra-reliable, low-latency...

NIST LabCAS: Data Driven Science Architecture and Resource

Ongoing
Biological data lie at the heart of innovation and artificial intelligence (AI) advances in the emerging biotechnology sector and serve as key strategic resources for achieving major breakthroughs in biomanufacturing, as summarized by the National Security Commission on Emerging Biotechnology's...
NIST Foundry for Living Measurement Systems

NIST Living Measurement Systems Foundry

Ongoing
To enable the production of high-throughput, high-quality data that meets the rapidly evolving needs of current and future stakeholders, NIST has established an automation facility for the growth, manipulation, sample preparation, and measurement of engineered microbes. The core of the facility...

NIST Materials Resource Registry

Ongoing
The MRR is a comprehensive inventory of high-level data collections, repositories, databases, tools, software, and services useful to materials research and design but located anywhere in the world. Its specialization for Materials Science is in the domain-specific metadata and vocabulary it can...

NIST Materials-focused Empirical Potentials Repositories and Efforts

Ongoing
SOFT MATTER WebFF: Force-field repository for organic and soft materials Frederick R. Phelan Jr., 1 and Huai Sun 2 1Materials Science and Engineering Division, NIST, Gaithersburg, MD 20899 2Aeon Technology Inc. and School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University...
Microbial Strain

NIST Microbial Strain Bank (NMSB)

Ongoing
Microorganisms of interest include but are not limited to those relevant to: biomanufacturing of advanced therapy products; rapid microbial testing; microbial therapeutics (e.g., live biotherapeutic products, probiotics, and fecal microbiota transplantations (FMTs)); infectious disease...
mass-in-vacuum precision mass comparator

The NIST Mise en Pratique since the Redefinition of the Kilogram

Ongoing
Realization Since the redefinition of the kilogram, the NIST Mass and Force Group has been closely involved with the NIST-4 Kibble balance project and its realization of the electronic kilogram via the Kibble Principle. Traceability post-realization is maintained through what is referred to as the...
NISTmAb RM8671 vial and 3D printed model

NIST Monoclonal Antibody Reference Material 8671

Ongoing
The NISTmAb material is a recombinant humanized IgG1κ expressed in murine suspension culture. It is an »150 kDa homodimer of two identical light chains and two identical heavy chains linked through both inter- and intra-chain disulfide bonds. The protein has low abundance post-translational...
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NIST Ocean Carbon Measurements

Ongoing
NIST is committed to sustaining the quality of ocean carbon measurements by developing capabilities to provide certified reference materials for the ocean carbonate system measurements and by conducting research to understand fundamental elements of the ocean carbon thermodynamic system. NIST Ocean...
group photo taken at NCWM 2023 Annual Meeting; Craig VanBuren, Don Onwiler, and Mahesh Albuquerque of NCWM, Laurie Locascio and Katrice Lippa of NIST, Gene Robertson of NCWM, David Sefcik

NIST OWM – NCWM: An Enduring Partnership

Ongoing
The National Conference on Weights and Measures (NCWM) was first held as the “First Annual Meeting of Sealers of Weights and Measures of the United States” in 1905 and as part of the National Bureau of Standards (NBS), which was the predecessor non-regulatory agency to the National Institute of...
Map of the Hawaiian islands showing outlines and major cities of the islands.

NIST U.S. Pacific Islands Program

Completed
To help address environmental research and resource management in the Pacific Islands region, the 111th U.S. Congress directed NIST to "expand its capabilities and resources into the Pacific region through a Pacific Islands component of NIST" and included funding to "expand its biodiversity storage...
NIST PS1

NIST PS1 Primary Standard for quantitative NMR (Benzoic Acid)

Completed
With explicit SI linkage, the overall impact of this apical reference material is profound—this primary standard, as well as forthcoming members of its class, provides technology transfer of chemical purity realization to the commercial sector for characterization of many thousands of organic...

NIST Rapid Microbial Testing Methods Consortium

Ongoing
The safety and quality of advanced therapies, including cell therapy, gene therapy, and tissue engineered products, must be maintained prior to patient administration. The culture-based compendial methods currently used to assess product purity (specifically to ensure absence of microbial...

NIST/SEMATECH Engineering Statistics Handbook

Ongoing
Description: The project began with a request from SEMATECH, a consortium of major U.S. semiconductor manufacturers, to update the National Bureau of Standards (NBS) Handbook 91, Experimental Statistics. Handbook 91, written by Mary Natrella of the NBS Statistical Engineering Lab, was a best-selling...
Photograph of the NIST Standard Reference Photometer showing the component modules consisting of optical bench with sample and reference tubes, ozone generator module with controls and tubing, and control module with numeric LED displays.

The NIST Standard Reference Photometer for Ozone Measurement Traceability

Ongoing
The concentration of ozone in the atmosphere continues to be an important global issue both scientifically and politically. Stratospheric ozone protects the Earth from harmful UV radiation, while tropospheric ozoneis a major health concern and contributes to global climate change as a greenhouse gas...
Evolution of Flat-histogram Monte Carlo Simulation

NIST Standard Reference Simulation Website

Ongoing
Molecular simulations, in particular Monte Carlo Molecular Simulation and Molecular Dynamics Simulation, are methods for computing the properties of some kind of system, for which the intermolecular interactions are specified via mathematical relationships derived from statistical mechanics. Since...
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