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Projects/Programs

Topic Area
Displaying 1051 - 1075 of 1616

NIST Rapid Microbial Testing Methods Consortium

Ongoing
The safety and quality of advanced therapies, including cell therapy, gene therapy, and tissue engineered products, must be maintained prior to patient administration. The culture-based compendial methods currently used to assess product purity (specifically to ensure absence of microbial

NIST/SEMATECH Engineering Statistics Handbook

Ongoing
Description: The project began with a request from SEMATECH, a consortium of major U.S. semiconductor manufacturers, to update the National Bureau of Standards (NBS) Handbook 91, Experimental Statistics. Handbook 91, written by Mary Natrella of the NBS Statistical Engineering Lab, was a best-selling
Photograph of the NIST Standard Reference Photometer showing the component modules consisting of optical bench with sample and reference tubes, ozone generator module with controls and tubing, and control module with numeric LED displays.

The NIST Standard Reference Photometer for Ozone Measurement Traceability

Ongoing
The concentration of ozone in the atmosphere continues to be an important global issue both scientifically and politically. Stratospheric ozone protects the Earth from harmful UV radiation, while tropospheric ozoneis a major health concern and contributes to global climate change as a greenhouse gas
Evolution of Flat-histogram Monte Carlo Simulation

NIST Standard Reference Simulation Website

Ongoing
Molecular simulations, in particular Monte Carlo Molecular Simulation and Molecular Dynamics Simulation, are methods for computing the properties of some kind of system, for which the intermolecular interactions are specified via mathematical relationships derived from statistical mechanics. Since

NIST Stars

Ongoing
A wide range of scientific and technical fields will benefit from having SI traceable stellar radiometric flux measurements (SI Stars). Weather and climate research satellites could use SI Stars for on orbit calibration of their spectroradiometers and astronomers could use them to calibrate
Image of a fentanyl mass spectrum shown in a lab notebook

NIST and the SWGDRUG Mass Spectral Reference Library of Seized Drugs

Ongoing
Synthetic drugs such as fentanyl and its analogues are driving an unprecedented epidemic of overdose deaths in the United States. Clandestine labs create these new substances in part to evade law enforcement. This places a major burden on federal, state, and local law enforcement agencies to
Cannabis

NIST Tools for Cannabis Laboratory Quality Assurance

Ongoing
Since the 1970s, cannabis (marijuana and hemp) and its constituent, Δ 9-tetrahydrocannabinol or THC, have been classified as Schedule I controlled substances. Seized evidence is tested by forensic laboratories, which verify the identity of the plant through macro- and microscopic evaluation and the
Photograph of hundreds of gas cylinders in a gas storage facility.

NIST Traceable Reference Material Program for Gas Standards

Ongoing
The Gas Mixture SRM, NTRM, and EPA Protocol Programs provide a mechanism to produce needed calibration gas standards with a well-defined traceability. These mixtures are specified in the Code of Federal Regulations (CFR) to calibrate instruments to be used to monitor regulated emissions. The NTRM
Reference Measurement System for Urine Albumin

NIST Urine Albumin Standardization Program

Ongoing
Kidney disease is a major global economic and public health issue, with chronic kidney disease (CKD) representing one of the top 10 most prominent causes of death worldwide. The public health and economic impact of CKD and other kidney diseases has led to the need for the accurate detection of
Test tube illustrating NIST cell-free workshop topics

NIST Workshops on Cell-Free Expression Systems

Ongoing
NIST has co-hosted two cell-free workshops. NIST CELL-FREE (Comparable Engineered Living Lysates For Research Education and Entrepreneurship) Workshop (2019) The NIST CELL-FREE workshop took place in La Jolla, CA in February 2019, in collaboration with the J. Craig Venter Institute (JCVI). The
Example unit of NIST Research Grade Test Material (RGTM) 10197 NISTCHO Test Material

NISTCHO

Ongoing
NISTCHO, a new mammalian cell line of interest to the biopharmaceutical and biomanufacturing communities, is now available from the National Institute of Standards and Technology. This Chinese hamster ovary (CHO) cell line has been engineered by MilliporeSigma to express a non-originator version of
Johnson Noise Thermometer system

Noise Thermometry

Ongoing
The project has also created a quantum-based electronic temperature standard that uses the ACJVS in conjunction with measurement of the Johnson noise -- random electrical noise caused by thermal agitation in a conductor -- in resistors at arbitrary temperatures. This Johnson noise thermometry system
nanophotonic

Nonlinear nanophotonic control of light

Ongoing
Light-matter interactions with nonlinear materials provide a powerful tool for converting optical fields from one state to another. For example, nonlinear wavelength conversion leverages efficient scattering of photons of a single frequency to another, enabling generation of coherent sources across
Image depiction of: To connect two nodes operating at different wavelengths, there are generally two strategies: (1) use quantum frequency conversion or quantum transduction to convert the wavelength of the photon emitted by one node to the wavelength of the second node, or (2) connect the two nodes using an entangled photon pair source whose two photons have wavelengths that match the two nodes. Both techniques involve nonlinear optics.

Nonlinear Optics for Quantum Information and Networking

Ongoing
Quantum networking and distributed quantum sensing will require photonic links (so called flying qubits) to connect nodes and enable scaling to larger distances and network sizes. An interconnect may consist of a photon going from one node to another where both nodes operate at the same wavelength
Northeast Corridor project elements

Northeast Corridor Urban Test Bed for Greenhouse Gas Emissions

Ongoing
The NEC project includes multiple measurement and analysis components. The backbone of the NEC project is a network of in-situ CO2 and CH4 observation stations with continuous high-accuracy mole fraction measurements of these two greenhouse gases. In addition, the University of Maryland ( FLAGG-MD)
NPS Data Hub

Novel Psychoactive Substance (NPS) Data Hub

Ongoing
A growing portion of forensic drug laboratory’s workload is the identification of novel psychoactive substances (NPSs), or emerging synthetic drugs (ESDs), presented as exhibit materials after seizure events. A pressing need exists for the rapid characterization of both the active ingredient(s) and
schematic of the MOTIS ion beam source

Novel Sources for Focused-ion Beams

Completed
Commercial focused ion beams (FIBs) are used in a wide variety of applications. For example, they serve as diagnostic tools, slicing through a nanodevice to expose its internal structure. They can also shape nanoscale materials either by adding atoms to a structure or by shaving them off. And they

NRC Postdoctoral Associate Program

Ongoing
Description: The Statistical Engineering Division (SED), within the Information Technology Laboratory, serves primarily as a research and consulting group working with the NIST scientific staff. Members of the Division engage in research in the areas of statistical graphics, reliability, linear

Numerical Reproducibility

Ongoing
The Information Systems group in ITL is developing a program in numerical reproducibility, which has been funded through several projects. Issues with numerical reproducibility are becoming increasingly significant, for several reasons Increased use of parallel computing has caused order of
OOF3D Logo

Object Oriented Finite Elements (OOF)

Ongoing
The best and most current information about the OOF software, including current downloads, can be found at the main OOF site. The general workflow of the OOF software begins with a 2D or 3D image. OOF provides tools for maniupating the image to highlight scientifically important features, and to
underwater view of MOBY

Ocean Color

Ongoing
The primary reference instrument for the United States and most international ocean-color sensors is the Marine Optical Buoy (MOBY), an automated radiometric system operated by NOAA and deployed about 20 km offshore from Lanai, Hawaii, where the atmospheric and water conditions support utilizing