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Office of the Director

Projects/Programs

Displaying 1201 - 1225 of 1601
Responsible Network Usage pscr

Public Safety Mobile Application Security

Ongoing
The nationwide public safety broadband network will provide first responders with modern access to data. This new access to multimedia (audio/video), situational awareness data, and operations functionality will enhance first responder’s effectiveness and efficiency. While mobile applications can
Research Library Lobo

Publishing Services

Ongoing
The NIST Research Library occupies the unique position of serving NIST both as publisher of the NIST Technical Series, and in an archival capacity, responsible for collecting and preserving copies of NIST's grey literature. Over the last 15 years, the Library's publishing services have evolved from

Pushing the Limits of Measurement Accuracy in Atom Probe Mass Spectrometry

Ongoing
Isotopic Analysis for Isotopic Geochemistry, Nuclear Safety, and Materials Science : Atom probe tomography has a significant advantage over other forms of mass spectrometry, which typically have a combined efficiency < 5%, in terms of ionization and detection efficiency. Commercial atom probe
NIST developed test artifact for AM

Qualification for Additive Manufacturing Materials, Processes, and Parts

Completed
Objective: Develop test methods and protocols, provide reference data, and establish requirements to reduce the cost and time to qualify AM materials, processes, and parts. Technical Idea: Qualification of AM materials, processes, and parts is critical to enabling the AM industry to crack into the

Qualification for AM Feedstocks, Machines and Processes

Completed
Objective - To develop, utilize, and analyze test methods and protocols for characterizing the feedstocks, machines, and processes in metal-based additive manufacturing to enable optimum usage and to reduce the cost and time needed for qualification. What is the Technical Idea? Qualification of AM

Quality Assessment of Cryogenic Electron Microscopy Images

Ongoing
Manufacturing a vaccine based on packaging mRNA in lipid nanoparticles requires a full characterization of concentrations and distributions of mRNA and LNPs, as well as all manufacturing conditions. Such experiments generate hundreds of terabytes (TBs) of images and pose challenges on trusted
DPO sensor

Quantifying the environmental contributions to mass change

Ongoing
Experiments using two types of centimeter scale oscillators are described: the double paddle oscillator (DPO) and a commercial quartz crystal microbalance (QCM). Double Paddle Oscillator (DPO) Since mass changes are mostly on the surface of mass artifacts, we have implemented a micro-weighing sensor

Quantifying Uncertainty in Accelerometer Sensitivity Studies

Ongoing
DESCRIPTION: International Key Comparisons are performed. The key comparison reference value for charge sensitivity as a function of frequency and the accompanying uncertainty are the principal objectives of these studies. In a suggested mixed effects model several methods for evaluation of this

Quantitative, Cell-based Immunofluorescence Assays

Completed
Analysis of signaling events within individual cells with microscopy imaging has several advantages over non-imaging techniques. The principal advantage of imaging cytometry over plate reader assays and even other single cell techniques such as flow cytometry is the potential for collection of

Quantitative Flow Cytometry Measurements

Ongoing
Flow cytometry is an essential tool for: basic biotechnological and immunological research, the clinical discovery of potential therapeutics, development and approval of drugs and devices, disease diagnosis, and therapeutic treatment and monitoring For example, flow cytometry is commonly used in pre

Quantitative Information from Images

Ongoing
Projects: Quantifying Amount of Material through Light Measurement Fluorescence and Luminescence Imaging for Surgical Guidance Fluorescence-guided imaging devices are being used for navigation in minimally invasive surgical procedures to increase a patient’s positive clinical outcomes and shorten
MRI standards

Quantitative MRI

Ongoing
Future directions may focus on multimodal imaging, techniques that use MRI as either a base or as a complimentary technique. Multimodal imaging combines information from two or more imaging modalities such as MRI, computed tomography (CT), positron emission tomography (PET), and ultrasound (US)
Schematic of unresolved imaging of a periodic structure. Extracting deep-subwavelength information from such images requires mastery of several techniques; this project seeks to integrate machine learning for metrology.

Quantitative Nanoscale Imaging Through Artificial Intelligence

Ongoing
This project extends optical capabilities for the characterization of nanoscale devices as they increase in complexity, with challenging new materials properties, thicknesses, and length scales that challenge simplistic applications of the fundamental equations of electromagnetism. Critical
Quantum Hall System

Quantum anomalous Hall effect Theory

Ongoing
The quantum anomalous Hall effect is a phenomenon in which certain magnetic insulators exhibit a zero-field Hall resistance value, 𝑅 𝐻, that is precisely quantized in terms of fundamental constants of nature: 𝑅 𝐻 = ℎ/𝑛𝑒 2, where ℎ is Planck's constant, 𝑒 is the charge of the electron and 𝑛 is a
Quantum Biophotonics

Quantum Biophotonics

Ongoing
Applying recent advances in single-photon detection along with novel data processing methods developed in the quantum optics community opens fundamentally new opportunities for faint-light metrology down to that related to just a single molecule – i.e. precisely the conditions for bio-optical
Boulder Cryogenic Quantum Testbed

Quantum Characterization

Ongoing
The BCQT serves as a resource to academic and industry quantum research groups for measurement of superconducting microwave resonators in a well-characterized cryogenic environment using traceable, open-source methods developed in broad consultation with companies, universities, and NIST. This

Quantum Communications and Networks

Ongoing
Positions - accepting applications: We are accepting applications for Postdoc and/or Guest Researcher experimental optics positions in the Quantum Communications and Networking Project. US Citizens are strongly recommended to apply. Candidates should have expertise in experimental optics and be
Quantum Computations in Optical Lattices

Quantum Computation and Simulation with Neutral Atoms

Ongoing
Advances in quantum information have the potential to significantly improve sensor technology, complete computational tasks unattainable by classical means, provide understanding of complex many-body systems, and yield new insight regarding the nature of quantum physics. At NIST and around the world
This image shows a planar rf ion trap designed for experiments with magnetically-driven quantum gates.

Quantum Computing with Trapped Ions

Ongoing
Quantum Computing with Trapped Ions We pursue proof-of-concept experiments in quantum information processing and quantum control with trapped ions. In addition to pushing current limits on traditional quantum gate-based architectures for quantum computing we explore alternative approaches to
Example of a star-mesh device design

Quantum Conductance

Ongoing
The quantum Hall effect (QHE), and devices that exhibit it, will continue to serve as the foundation of the ohm while also expanding its territory into other SI derived units. The world adopted the quantum SI in 2019, and it remains essential that the global metrology community pushes forth and
AMO physics

Quantum Many-Body Physics, Quantum Optics, and Quantum Information

Ongoing
Differences between typical AMO and condensed matter systems bring with them exciting new physics. In contrast to condensed matter systems, AMO systems are often studied far out of equilibrium, are evolving in time, and are subject to dissipation. As a result, many-body AMO systems open a whole new
chip experiment

Quantum matter from atomic gases

Ongoing
Ultracold atoms are a very different sort of system than conventional materials, composed of a few hundred to a few hundred million atoms, with densities ranging from 10 12 cm -3 to 10 15 cm -3, and at temperatures from below 1 nK to a couple uK. These atomic systems are unique in the simplicity of
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