An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Max K. Ferguson, Seongwoon Jeong, Kincho H. Law, Anantha Narayanan Narayanan, Svetlana Levitan, Jena Tridivesh, Yung-Tsun Lee
The use of deep convolutional neural networks is becoming increasingly popular in the engineering and manufacturing sectors. However, managing the distribution of trained models is still a difficult task, partially due to the limitations of standardized
The DNA sequencing technologies in use today produce either highly accurate short reads or less-accurate long reads. We report the optimization of circular consensus sequencing (CCS) to improve the accuracy of single-molecule real-time (SMRT) sequencing
Joshua Hunsberger, Martha Lundberg, Julie Allickson, Claudia Zylberberg, Sarah Beachy, Carl Simon
This perspective article is inspired by a workshop entitled "Cell and Tissue Manufacturing Innovation" that was held at the Tissue Engineering and Regenerative medicine Society (TERMIS). Five main concepts are discussed: 1) the US National Academies' Forum
Standard-sized ampoules for radioactive solution standards have been employed by the National Institute of Standards and Technology (NIST) for nearly the past 70 years. This note briefly summarizes the origins and history of the five different batches of
John A. Horst, Thomas D. Hedberg, Allison Barnard Feeney
Digital thread standards for both dimensional metrology and industrial machine tool operations have been defined in standards organizations and successfully implemented in several commercial manufacturing production operations. A next step is to define a
Christine A. Donnelly, Justus A. Brevik, Nathan E. Flowers-Jacobs, Peter F. Hopkins, Paul D. Dresselhaus, Samuel P. Benz
For the first time, we synthesize single- and multiple-tone waveforms at gigahertz frequencies from arrays of Josephson junctions and demonstrate quantum-locked operation over a range of experimental input parameters. We first use a lumped-element circuit
George C. Rhoderick, Christina Cecelski, Walter R. Miller Jr., David Worton, Sergi Moreno, Paul Brewer, Joele Viallon, Faraz Idrees, Philippe Moussay, Yong D. Kim, Dal H. Kim, Sangil Lee, Annarita Baldan, Jianrong Li
Volatile organic compounds (VOCs) are a group of gas-phase compounds present in the atmosphere that affect air quality and Earth's climate. Halocarbons, a subset of this group, are strong greenhouse gases and are linked to stratospheric ozone depletion
Christine A. Donnelly, Justus Brevik, Nathan Flowers-Jacobs, Anna Fox, Paul Dresselhaus, Peter F. Hopkins, Samuel Benz
We present time-domain electrical measurements and simulations of the quantized voltage pulses that are generated from series-connected Josephson junction (JJ) arrays. The transmission delay of the JJ array can lead to a broadening of the net output pulse
Boonserm Kulvatunyou, Nenad Ivezic, Hakju Oh, Scott Nieman
With increasing use of the Industrial Internet of Things, including smart sensors, smart devices, smart machines, and software services, standards are playing increasingly important role to reduce risks associated with investments in these devices. This
The ASTM E3012-16 Standard Guide for Characterizing Environmental Aspects of Manufacturing Processes provides guidelines for formally characterizing manufacturing processes. However, the difficulty that has arisen in the early use of the standard
Justin M. Zook, Nathanael D. Olson, Marc L. Salit, Aaron Wenger, Chunlin Xiao, Robert Sebra
Genome In a Bottle (GIAB) is a consortium hosted by the National Institute of Standards and Technology whose primary objective is the development and characterization of human genomic reference materials. The consortium includes representatives from
Loren Albert, Katherine Cushman, Yuqin Zong, David Allen, Luis Alonso, James Kellner
Remote sensing of solar induced chlorophyll fluorescence (SIF) promises a significant advance in our ability to quantify gross primary productivity across spatial scales. Because the fluorescence emission is usually 5 % of recorded canopy radiance
John R. Sieber, Antonio M. Possolo, Michael S. Epstein
Many older certified reference materials have certificates of analysis that do not fully comply with ISO Guide 31. This applies to many NIST Standard Reference Materials (SRM) that have published uncertainty estimates not compliant with the GUM or have no
This document presents supporting documentation for a reference implementation of the Unit Manufacturing Process (UMP) information model presented in ASTM E3012, Standard Guide for Characterizing Environmental Aspects of Manufacturing Processes. A version
William Z. Bernstein, Cesar D. Tamayo, David Lechevalier, Michael Brundage
Life cycle assessment (LCA) carries significant uncertainties and imprecision due to a number of factors, including the framework's linearity assumptions and the wide use of aggregate unit processes in practice. The goal of this work is to exploit the unit
To bolster the efficiency and performance of maintenance work in manufacturing-maintenance being one of the key components to ensuring successful long-term operations-it is becoming increasingly necessary to ensure that maintenance operations are capable
Justin M. Zook, Jennifer H. McDaniel, Marc L. Salit, Nathanael D. Olson, Justin M. Wagner
Benchmark small variant calls are required for developing, optimizing and assessing the performance of sequencing and bioinformatics methods. Here, as part of the Genome in a Bottle (GIAB) Consortium, we apply a reproducible, cloud-based pipeline to
NIST Handbook 150-1, NVLAP Energy Efficient Lighting Products, presents the technical requirements and guidance for the accreditation of laboratories under the NVLAP Energy Efficient Lighting Products LAP. The 2018 revision aligns this handbook with the
Jeanice M. Brown Thomas, David L. Duewer, Margaret C. Kline, William A. MacCrehan, Robert Paule, Reenie Parris, Willie May, Robert Schaffer
From 1984 to 2017, the National Institute of Standards and Technology (NIST) and its precursor the National Burearu of Standards (NBS) coordinated what became the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure
In the last two decades, the microfluidics/lab-on-a-chip field has evolved from the concept of micro total analysis systems, where systems with integrated pretreatment and analysis of chemicals were envisioned, to what is known today as lab-on-a-chip
Dimitrios Georgakopoulos, Ilya F. Budovsky, Samuel Benz
We have developed a system to extend, by a factor of up to 1000, the voltage range over which Josephson arbitrary waveform synthesizers (JAWS) can be used in ac voltage metrology. The system is based on a precision inductive voltage divider, with a lock-in
Solutions of organic analytes of known mass fraction are typically used to calibrate the measurement processes used to determine these compounds in matrix samples. Appropriate value assignments and uncertainty calculations for calibration solutions are
David L. Duewer, Jacolin A. Murray, Laura J. Wood, Stephen A. Wise
Extraction, chromatographic separation, and quantification of low-concentration organic compounds in complex matrices are core challenges for reference material producers and providers of calibration services. Evidence of successful participation in formal
In response to needs of a government-wide initiative in nanotechnology led by a subcommittee within the White Houses Office of Science and Technology Policy, NIST established a nanotechnology environmental, health, and safety (nano-EHS) research program