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Nanotechnology

Nanobiotechnology

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  • Published Date
Displaying 126 - 141 of 141

Competitive Adsorption of Thiolated Polyethylene Glycol and Mercaptoproprionic acid on Gold Nanoparticles Measured by Physical Characterization Methods

May 24, 2010
Author(s)
De-Hao D. Tsai, Frank W. DelRio, Robert I. MacCuspie, Tae Joon Cho, Michael R. Zachariah, Vincent A. Hackley
Adsorption kinetics between thiolated polyethylene glycol (SH-PEG) and mercaptoproprionic acid (MPA) on gold nanoparticles (Au-NP) were studied using dynamic light scattering (DLS) and electrospray differential mobility analysis (ES-DMA). Through a

Fluorinated Copolymer Nanoparticles for Multimodal Imaging Applications

February 18, 2010
Author(s)
Mark M. Bailey, Christine M. Mahoney, Elodie Dempah, Jeffrey M. Davis, Matthew Becker, Supang Khondee, Eric J. Munson, Cory J. Berkland
Nanomaterials have emerged as valuable tools in biomedical imaging techniques, such as magnetic resonance imaging (MRI), fluorescence, positron emission tomography (PET), and others. Some have been designed to serve as multimodal imaging agents, combining

Nanoscale Measurements With the TSOM Optical Method

January 4, 2010
Author(s)
Ravikiran Attota
A novel through-focus scanning optical microscope (TSOM - pronounced as 'tee-som') technique that produces nanometer dimensional measurement sensitivity using a conventional optical microscope by analyzing images obtained at different focus positions will

Interaction of Gold Nanoparticles with Common Human Blood Proteins

December 18, 2009
Author(s)
Silvia H. De Paoli Lacerda, Jung J. Park, Curtis W. Meuse, Denis Pristinski, Matthew Becker, Jack F. Douglas
Gold nanoparticles (NPs) provide a promising platform for diagnostics and therapy, as well as other biomedical applications. The recent literature, however, contains conflicting data regarding the cytotoxicity of NPs. We have thus performed an array of

Probing Dynamic Fluorescence Properties of Single and Clustered Quantum Dots Towards Quantitative Biomedical Imaging of Cells

October 28, 2009
Author(s)
Hyeong G. Kang, Fuyuki Tokumasu, Matthew L. Clarke, Zhenping Zhou, Jianyong Tang, Tinh Nguyen, Jeeseong Hwang
We present results on dynamical fluorescence properties of bioconjugated nanocrystals or quantum dots (QDs) in different chemical and physical environments. A variety of QD samples were prepared and compared: isolated individual QDs, QDs aggregated into

Nanoscale Measurements with a Through-Focus Scanning-Optical-Microscope

July 15, 2009
Author(s)
Ravikiran Attota, Richard M. Silver, Thomas A. Germer
We present a novel optical technique that produces nanometer dimensional measurement sensitivity using a conventional optical microscope, by analyzing through-focus scanning-optical-microscope (TSOM) images obtained at different focus positions. In

Detection of food pathogens by on-chip PCR

September 3, 2008
Author(s)
Pierre-Alain Auroux, Barbara Jones
This is a chapter that will be part of a book on detection of pathogens using state-of-the-art detection methods. We are focusing on the use of microfluidic chips to implement DNA analysis of pathogens by the polymerase chain reaction.

Sizing the Bacillus anthracis PA63 Channel with Nonelectrolyte Poly(ethylene glycols)

August 1, 2008
Author(s)
Brian J. Nablo, Kelly Halverson, Joseph W. Robertson, Tam Nguyen, Rekha Panchal, Rick Gussio, Sina Bavari, Oleg V. Krasilnikov, John J. Kasianowicz
Non-electrolyte polymers of poly(ethylene glycol), PEG, were used to estimate the diameter of the ion channel formed by Bacillus anthracis protective antigen 63, PA63. Based on the ability of different molecular weight PEGs to partition into the pore and

Nanoscopic Porous Sensors

July 1, 2008
Author(s)
John J. Kasianowicz, Joseph W. Robertson, Elaine Chan, Joseph E. Reiner, Vincent M. Stanford
There are thousands of different nanometer-scale pores in biology,many of which act as sensors for specific chemical agents. Recent work suggests that protein and solid-state nanopores have many potential uses in a wide variety of analytical applications
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