Nanobiotechnology

News and Updates

Sneezes, Rain Clouds and Ink Jets: NIST Improves the Ability of Optical Microscopes to Measure the Volume of Microdroplets

December 20, 2021

Sneezes, rain clouds, and ink jet printers: They all produce or contain liquid droplets so tiny it would take several billion of them to fill a liter bottle

A woman (Diane Nelson) in a mask and lab coat works with plastic test tubes at a lab bench.

Spotlight: Taking a Closer Look at Human Lungs With Postdoctoral Researcher Diane Nelson

December 9, 2021

A breath of fresh air — Diane Nelson recently joined NIST as a postdoctoral researcher, open to opportunities and committed to her craft. The inner workings of

NIST Publishes a Beginner’s Guide to DNA Origami

January 8, 2021

In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature

Projects and Programs

PTIR combines the spatial resolution of AFM with the specificity of absorption spectroscopy

Nano-Chemical Imaging and -Spectroscopy (IR, nIR, VIS)

Ongoing

Conventional techniques for analyzing chemical composition, such as infrared (IR) microscopy often miss critically important nanoscale details. To overcome this

Schematic showing DNA origami in a laser beam

DNA Origami for Precise Manufacturing of Nanoscale Structures

Ongoing

Over the past decade nanoscale science has produced varied and fascinating nanostructures with an extraordinary range of interesting and useful properties. In

Fundamental Interaction Mechanisms of Engineered Nanomaterials with DNA

Ongoing

We utilized isotope-dilution liquid chromatography/mass spectrometry (LC/MS) to determine the levels of the oxidatively damaged DNA bases, 8

Metrologies for Nanobiomaterials in Artificial Photosynthesis

Completed

Novel technologies for solar fuel production are expected to increasingly contribute to meeting our nation's environmental and energy needs. Mimicking nature's

Publications

Addressable graphene encapsulation of wet specimens on a chip for optical, electron, infrared and X-ray based spectromicroscopy studies

October 15, 2021

Author(s)

Andrei Kolmakov

Label-free spectromicroscopy methods offer the capability to examine complex cellular phenomena. Electron and X-ray based spectromicroscopy methods, though

Parametric optimization of an air-liquid interface system for flow through inhalation exposure to nanoparticles: assessing dosimetry and intracellular uptake of CeO2 nanoparticles

September 29, 2021

Author(s)

Lars Leibrock, Harald Jungnickel, Jutta Tentschert, Aaron Katz, Blaza Toman, Elijah Petersen, Frank Bierkandt, Ajay V. Singh, Peter Laux, Andreas Luch

Air-liquid interface (ALI) systems have been widely used in recent years to investigate the inhalation toxicity of many gaseous compounds, chemicals, and

Critical considerations for the design of multi-organ microphysiological systems (MPS)

September 9, 2021

Author(s)

Mridu Malik, Yang Yang, Parinaz Fathi, Gretchen Mahler, Mandy Esch

The process of identifying new drugs and getting them approved for use in patients requires extensive preclinical studies and clinical trials. Preclinical

Nanopore sensing: a physical-chemical approach

September 1, 2021

Author(s)

Joseph W. Robertson, Madhav Ghimire, Joseph Reiner

Protein nanopores have emerged as an important class of sensor, for the understanding of biophysical processes, such as molecular transport across membranes