Nanobiotechnology

News and Updates

A new twist on measuring spin: NIST Develops Microresonator to Study Electron Spin in Small Volumes

November 17, 2020

Researchers at the National Institute of Standards and Technology (NIST) have developed a device to detect a quantum property of electrons, known as spin, in

NIST Scientists Get Soft on 3D Printing

September 22, 2020

Researchers at the National Institute of Standards and Technology (NIST) have developed a new method of 3D-printing gels and other soft materials. Published in

Making the DNA Melt Curve More Accurate

August 18, 2020

DNA is not only the blueprint of life; it has become the backbone for making tiny structures that can be inserted into the human body to diagnose and treat

NIST Goes With the (Slow) Flow: New Technique Could Improve Biotech, Precision Medicine

September 26, 2019

Researchers at the National Institute of Standards and Technology (NIST) have developed an optical system that accurately measures the flow of extraordinarily

Projects and Programs

PTIR combines the spatial resolution of AFM with the specificity of absorption spectroscopy

Nano-Chemical Imaging and -Spectroscopy (IR, nIR, VIS)

Conventional techniques for analyzing chemical composition, such as infrared (IR) microscopy often miss critically important nanoscale details. To overcome this

A micromechanical bulk acoustic resonator that uses phononic crystal tethers to achieve a quality factor approaching the fundamental dissipation limit (fxQ can be as large as 1.2 x 1013 Hz)

Micro- and Nanoelectromechanical Systems

Microelectromechanical systems (MEMS) are integrated devices with critical applications in sensing, timing, signal processing, and biomedical diagnostics, and

Development of surface functionalized engineered nanomaterials for biological applications

The main research theme is the design and implementation of novel surface functionalities on engineered nanomaterials, by chemical approach, for their

Schematic showing DNA origami in a laser beam

DNA Origami for Precise Manufacturing of Nanoscale Structures

Over the past decade nanoscale science has produced varied and fascinating nanostructures with an extraordinary range of interesting and useful properties. In

Publications

Analysis and Uncertainty Quantification of DNA Fluorescence Melt Data: Applications of Affine Transformations

October 15, 2020

Author(s)

Paul N. Patrone, Anthony J. Kearsley, Jacob M. Majikes, James A. Liddle

Revealing thermodynamics of DNA origami folding via affine transformations

June 4, 2020

Author(s)

Jacob M. Majikes, Paul N. Patrone, Daniel R. Schiffels, Michael P. Zwolak, Anthony J. Kearsley, Samuel P. Forry, James A. Liddle

Structural DNA nanotechnology, as exemplified by DNA origami, has enabled the design and construction of molecularly precise objects for a myriad of

Precise pitch-scaling of ultra-scaled carbon nanotube arrays within 3D DNA nano-trenches

May 22, 2020

Author(s)

Jason K. Streit, Jeffrey A. Fagan, Ming Zheng, Wei Sun, Peng Yin, Jie Shen, Zhao Zhao, Hareem Maune

Precise assembly of carbon nanotubes (CNTs) into densely-aligned uniformly parallel arrays has been the missing link towards the emerging ultra-scaled post-Si

Infrared and Raman chemical imaging and spectroscopy at the nanoscale

May 19, 2020

Author(s)

Dmitry Kurouski, Alexandre Dazzi, Renato Zenobi, Andrea Centrone

The advent of nanotechnology, and the need to understand the chemical composition at the nanoscale, has stimulated the convergence of IR and Raman spectroscopy