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Health / Clinical diagnostics

Medical imaging

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Displaying 26 - 50 of 128

Magnetic Resonance Imaging Biomarker Calibration Service: NMR Measurement of Isotropic Water Diffusion Coefficient

March 30, 2023
Author(s)
Stephen E. Russek, Katy Keenan, Karl Stupic, Nikki Rentz, Michael Boss, Kevin J. Coakley, Amanda Koepke, Cassandra Stoffer
This document describes a calibration service to measure the water diffusion coefficient, or diffusivity, in reference materials and tissue mimics using nuclear magnetic resonance (NMR) techniques. This calibration is restricted to materials which exhibit

Three-dimensional, label-free cell viability measurements in tissue engineering scaffolds using optical coherence tomography

March 14, 2023
Author(s)
Greta Babakhanova, Anant Agrawal, Deepika Arora, Allison Horenberg, Jagat Budhathoki, Joy Dunkers, Joe Chalfoun, Peter Bajcsy, Carl Simon Jr.
In the field of tissue engineering, 3D scaffolds and cells are often combined to yield constructs that are used as therapeutics to repair or restore tissue function in patients. Viable cells are required to achieve the intended mechanism of action for the

Extreme Bottom-up Gold Filling of High Aspect Ratio Features

February 27, 2023
Author(s)
Daniel Josell, Thomas P. Moffat
Where copper interconnects fabricated using superconformal electrodeposition processes have enabled dramatic advances in microelectronics over the last quarter century, gold filled gratings fabricated using superconformal 〖Bi〗^(3+)-mediated bottom-up

Certification of Standard Reference Material(R) 2196 Axial Resolution Standard for Optical Medical Imaging

February 7, 2023
Author(s)
Jeeseong C. Hwang, Kimberly Briggman, Nikki Rentz, Hyun-Jin Kim, David W. Allen, Lee J. Richter, Sowon Yoon, John Lu
Medical imaging devices and systems must be calibrated to ensure uniformity and reliability of test results. A standard reference material (SRM) or "phantom", as it is known in the medical imaging community, is used to replicate fundamental characteristics

Mechanism of Bismuth Stimulated Bottom-up Gold Feature Filling

December 30, 2022
Author(s)
Daniel Josell, Trevor Braun, Thomas P. Moffat
The mechanism that underlies 〖Bi〗^(3+)-stimulated extreme bottom-up Au filling of trenches and vias in slightly alkaline 〖Na〗_3 Au(〖SO〗_3 )_2+〖Na〗_2 〖SO〗_3 electrolytes is explored. The remarkable void-free feature filling and self-passivation behavior

Spatial frequency domain Mueller matrix imaging

December 14, 2022
Author(s)
Joseph Chue-Sang, Maritoni Litorja, Aaron Goldfain, Thomas A. Germer
Significance: Mueller matrix polarimetry (MMP) and spatial frequency domain imaging (SFDI) are wide-field optical imaging modalities that differentiate tissue primarily by structure alignment and photon transport coefficient, respectively. Because these

Uncertainty estimation for 2D magnetic particle imaging

March 21, 2022
Author(s)
Mark-Alexander Henn, Klaus Natorf Quelhas, Solomon I. Woods
Magnetic Particle Imaging (MPI) has in recent years been established as a powerful imaging tool that measures thenon-linear magnetic response of magnetic particles to an applied field. Obtaining quantitative information fromthese images in the form of a

Calorimetry in Computed Tomography Beams

March 10, 2022
Author(s)
Heather H. Chen-Mayer, Ronald Tosh, Fred B. Bateman, Paul Bergstrom, Brian E. Zimmerman
A portable calorimeter for direct realization of absorbed dose in medical computed tomography (CT) procedures was constructed and tested in a positron emission tomography (PET) CT scanner. The calorimeter consists of two small thermistors embedded in a

Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals

May 11, 2021
Author(s)
Aleksey Yevtodiyenko, Arkadiy Bazhin, Pavlo Khodakivskyi, Aurelien Godinat, Gyslain Budin, Marina Kunchulia, Giorgio Pietramaggiori, Sandra Scherer, Elena Goun, Sergey Polyakov, George P. Eppeldauer
Bioluminescent imaging (BLI) is one of the most powerful and widely used preclinical imaging modalities. However, the current technology relies on the use of transgenic luciferase-expressing cells and animals and therefore can only be applied to a limited

A Standard System Phantom for Magnetic Resonance Imaging

April 13, 2021
Author(s)
Maureen Ainslie, Michael A. Boss, Cecil Charles, Laurence Clarke, Jeffrey L. Evelhoch, Paul Finn, Derek L. Hill, Kathryn Keenan, Guoying Liu, Karl Stupic, Chun Yuan, Michele Martin, Maureen Ainslie, Nikki Rentz
A standard MRI system phantom has been designed and fabricated to assess scanner performance, scanner stability, scanner inter-comparability and accuracy of quantitative relaxation time imaging. The phantom is unique in having SI-traceability, a high level
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