Clinical diagnostics

News and Updates

NIST Researchers Develop a Breakthrough COVID-19 Detection Technology

October 2, 2023

“Only connect” is the most famous line in the British novelist E. M. Forster’s writings. Forster was urging the readers of his book Howard’s End to make

Illustration shows a gloved hand holding a puzzle piece that fits into the center of a puzzle showing the letter Y.

Researchers Fully Sequence the Y Chromosome for the First Time

August 23, 2023

What was once the final frontier of the human genome — the Y chromosome — has just been mapped out in its entirety.

Jun Ye: A Timely Profile

June 26, 2023

Physicist Jun Ye has a knack for making every second count—literally. At JILA, a joint research institute of the University of Colorado and the National

Projects and Programs

Trusted AI framework for a new class of Standard Reference Materials and Data with exquisitely characterized uncertainty for billions of properties

Ongoing

A new collaboration between NIST's Human Genomics Team , Mass Spectrometry Data Center , and Information Technology Laboratory to use and develop artificial

Genome in a Bottle

Ongoing

Consortium hosted by NIST dedicated to authoritative characterization of benchmark human genomes. Sign up for General GIAB and Analysis Team email lists

Development of Enhanced mRNA Amplification Using Microfluidics

Ongoing

In conjunction with NCI/NIH, NIST is developing methods to improve mRNA amplification from small biological samples. Typical sample processing requires

NIST PS1 Primary Standard for quantitative NMR (Benzoic Acid)

Completed

The "first-of-its-kind" in an entirely new class of reference material, NIST PS1 Primary Standard for quantitative NMR (Benzoic Acid) is now available! The PS

Publications

Recommendations for setting a criterion and assessing commutability of sample materials used in external quality assessment/proficiency testing schemes

November 2, 2023

Author(s)

Sverre Sandberg, Pernille Fauskanger, Jesper Johansen, Thomas Keller, Jeffrey Budd, Neil Greenberg, robert rej, MAURO PANTEGHINI, VINCENT DELATOUR, Ferruccio Ceriotti, Liesbet Deprez, Johanna Camara, Finlay MacKenzie, Alicia Lyle, Eline van der Hagen, Chris Burns, W. Greg Miller

It is important for external quality assessment materials (EQAMs) to be commutable with clinical samples; i.e., they should behave like clinical samples when

Certification of Standard Reference Material® 967b Creatinine in Frozen Human Serum

September 22, 2023

Author(s)

Johanna Camara, Elena Wood, Blaza Toman

Standard Reference Material (SRM) 967b Creatinine in Frozen Human Serum is intended for use in validating creatinine measurement procedures used by in vitro

Results of German external quality assessment schemes for SARS-CoV-2 antigen detection

August 14, 2023

Author(s)

Laura Vierbaum, Nathalie Wojtalewicz, Peter Grunert, Anika Zimmerman, Annemarie Scholz, Sabine Goseberg, Patricia Kaiser, Ulf Duehring, Christian Drosten, Victor Max Corman, Daniela Niemeyer, Holger F. Rabenau, Martin Obermeier, Andreas Nitsche, Janine Michel, Jim Huggett, Denise O'Sullivan, Simon Cowen, Peter Vallone, Megan Cleveland, Samreen Falak, Andreas Kummrow, Ingo Schellenberg, Heinz Zeichhardt, Martin Kammel

The COVID-19 pandemic illustrated the important role of diagnostic tests, including lateral flow tests (LFTs), in identifying patients and their contacts to

Recommendations for Setting a Criterion for Assessing Commutability of Secondary Calibrator Certified Reference Materials

August 11, 2023

Author(s)

W. Greg Miller, Thomas Keller, Jeffrey Budd, Jesper Johansen, Mauro Panteghini, Neil Greenberg, Vincent Delatour, Ferruccio Ceriotti, Robert Rej, Johanna Camara, Liesbet Deprez, Finlay MacKenzie, Alicia Lyle, Eline van der Hagen, Chris Burns, Pernille Fauskanger, Sverre Sandberg

A secondary higher-order calibrator is required to be commutable with clinical samples to be suitable for use in the calibration hierarchy of an end-user

Software

NIST's Integrated Colony Enumerator (NICE)

January 4, 2021

Enumeration of bacterial colonies on an agar plate is simple in concept, but automated colony counting is difficult due to variations in colony color, size

Curated Archive for COVID-19 Research Challenge Dataset (cord19-cdcs-nist)

This GitHub repository contains a downloadable snapshot of National Institute of Standards and Technology's COVID-19 Data Repository , curated from the COVID-19