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Jessica M. Torres, Christopher Stafford, Bryan D. Vogt
Understanding the mechanical properties of polymers at the nanoscale is critical in numerous emerging applications. While it has been widely shown that the Tg in thin polymer films decreases due to confinement effects, there is little known about the
Diana N. Zeiger, Jirun Sun, Gary E. Schumacher, Sheng Lin-Gibson
Polymerization shrinkage of dental composites results in leakage and may lead to secondary caries and restoration failure. This study tested the hypothesis that shrinkage and sites of potential leakage in human teeth evaluated using X-ray microcomputed
Christopher M. Stafford, Jun Y. Chung, Heqing Huang, Adam J. Nolte, Peter M. Johnson, Edwin P. Chan
The structure and properties of polymer interfaces play an integral role in numerous technological applications, particularly in the areas of coatings and adhesives. These interfacial interactions are dependent on a host of factors, including interfacial
Dimethacrylate-based composites have seen increased application in orthopedics, where materials are typically placed in direct contact with viable bone tissue. Since a number of material properties, including degree of conversion (DC), surface
Relaxation processes in viscous liquids and glasses have been studied extensively as these processes dictate polymer reliability in applications where a constant or cyclical load is applied. These relaxations processes may lead to permanent deformations or
Nancy Lin, Haiqing Hu, Li Piin Sung, Sheng Lin-Gibson
A simple and straightforward screening process to assess the toxicity and corresponding cell response of dental composites would be useful prior to extensive in vitro or in vivo characterization. To this end, gradient composite samples were prepared with
Yanyin Yang, Vinoy Thomas, Abby W. Morgan, Shauna M. Dorsey, Carl Simon Jr.
Gradients and arrays have become very useful to the fields of tissue engineering and biomaterials. Both gradients and arrays make efficient platforms for screening cell response to biomaterials. Graded biomaterials also have functional applications and
Joseph M. Antonucci, Justin N. O'Donnell, Gary E. Schumacher, Drago Skrtic
This study evaluates the bond strength and related properties of the photo-polymerizable, remineralizing amorphous calcium phosphate (ACP) polymeric composite/adhesive systems to dentin after various periods of aqueous aging at 37 oC. An experimental ACP
James A. Warren, D M. Saylor, Martin McDermott, D Patwardhan, Chang-Soo Kim
To improve functionality and performance, controlled drug release coatings comprised of drug and polymer are integrated with traditional medical devices, e.g. drug eluting stents. Depending on manufacturing conditions, these coatings can exhibit complex
Current methods to determine debonding/leakage at the tooth-composite interphase are qualitative or semi-quantitative. Our previous work introduced a 3D imaging technique to determine and visualize leakage and its distribution at the interface of cavity
Gale A. Holmes, Eun S. Park, Jae Hyun Kim, Walter G. McDonough, John R. Sieber, Haruki Kobayashi, Michael A. Riley, Kirk D. Rice
The use of high performance fibers (such as, poly[(benzo-[1,2-d;5,4-d ]-benzoxazole-2,6-diyl)-1,4-phenylene]1 (PBO), ultra-high molecular weight polyethylene2 (UHMWPE), and poly(p-phenylene terephthalamide)3 (PPTA)) in soft body armor (SBA) is well
Carl G. Simon Jr., Kaushik Chatterjee, Sheng Lin-Gibson, William E. Wallace, Marian F. Young
A combinatorial method to rapidly screen cell-material interactions in three-dimensional (3-D) culture format was developed for accelerating tissue engineering research. Hydrogels of poly(ethylene glycol) dimethacrylate (PEGDM) with gradients in
W Bumrongjaroen, Richard A. Livingston, Dan A. Neumann, Andrew J. Allen
A combination of small-angle and inelastic neutron scattering studies are presented to elucidate the different effects of Class F and Class C fly ash additions on microstructure development in hydrating cement (and concrete). Small angle neutron scattering
Winnie K. Wong-Ng, Z Yang, Y F. Hu, Qingzhen Huang, Nathan Lowhorn, Makoto Otani, James A. Kaduk, Martin L. Green, Q Li
The search for thermoelectric materials for power generation and for solid-state cooling have led to the increased interest of layered cobalt-containing oxides because of their thermal stability at high temperature and their desirable thermoelectric
Dimethacrylates typically used in dental composites are seeing increased applications in orthopedics, applications where cell-material contact is highly likely and often encouraged. Some formulations of dimethacrylate polymers and composites have been
Naomi Eidelman, A Colorni, Jirun Sun, M.C. Fishbein, A Diamant
A case of myocardial calcification is described in the Mediterranean white grouper, Epinephelus aeneus, cultured as broodstock in Eilat (Israel, Red Sea). Large calcified nodules and scar tissue were observed in the ventricular tissues. The chemical
Kyle J. Alvine, Yifu Ding, Hyun Wook Ro, Brian C. Okerberg, Alamgir Karim, Christopher L. Soles, Jack F. Douglas
Capillary forces play an active role in defining the equilibrium structure of nanoscale structures. This effect can be especially pronounced in soft materials such as polymers near or above their glass transition temperatures where material flow is
Shauna M. Dorsey, Sheng Lin-Gibson, Carl Simon Jr.
Statement of Purpose: We have investigated the ability of X-ray microcomputed tomography (CT) to make three-dimensional (3D) measurements of cell adhesion and proliferation in polymeric tissue engineering scaffolds [1]. Standard methods for measuring cell
Timothy P. Quinn, Colm Flannery, Damian S. Lauria, Douglas V. Gallagher, Kristi S. Anseth
Bioreactors for in vitro growth of engineered tissue (ET) would ideally include sensors that would continuously measure the functional quality of the construct during incubation. Principles of feedback control could then be used to optimize properties of
Murugan Ramalingam, Marian F. Young, Vinoy Thomas, Carl Simon Jr.
Statement of Purpose: We are developing combinatorial methods for screening cell-material interactions. Although previous approaches for rapid screening have used material libraries in the form of two-dimensional surfaces or films (2D), biomaterials are
Kaushik Chatterjee, Sheng Lin-Gibson, Marian F. Young, William E. Wallace, Carl Simon Jr.
Statement of Purpose: With few successful products in the market despite large investments in tissue engineering research, there is a need to accelerate tissue engineering research. Towards this objective, developing high-throughput platforms to rapidly
We describe a closed-form approach for performing a Kramers-Kronig (KK) transform on data of finite frequency range; the method is analytically exact and computationally simple and robust. In this approach we transform the frequency domain data to the time
Li Piin Sung, Aaron M. Forster, Haiqing Hu, Nancy Lin, Sheng Lin-Gibson
Multi-component formulations coupled with complex processing conditions govern the final properties of photopolymerizable dental composites. In this study, a single test substrate was fabricated to support multiple formulations with a gradient in degree of
Jessica M. Torres, Christopher Stafford, Bryan D. Vogt
In this work, the modulus of polymer thin films for a homologous series of poly(n-alkyl methacrylate)s will be discussed. In particular, the impact of the degree of undercooling from bulk Tg on the deviations will be explored as Tg is significantly
Jirun Sun, Yifu Ding, Nancy Lin, Marcus T. Cicerone, Christopher Soles, Sheng Lin-Gibson
The time dependence of cell alignment and morphology (i.e., elongation) on anisotropic nanoscale gratings is characterized. The behavior of pre-osteoblasts cultured on nanoscale gradient patterns of transparent photopolymerized dimethacrylates was