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Biomaterials

NIST's research examines the interactions among lab-made materials and biological systems, advancing the development of diagnostics and therapeutics, and improving the performance of biomaterials used in dentistry and regenerative medicine.

NIST's measurement methods and reference materials accelerate the development of lab-made materials that can help heal wounds or replace missing tissues, or be used to mimic human tissues for diagnostics or research. Our long partnership with the American Dental Association boasts advances such as the tooth-colored composites used to fill cavities and repair chipped teeth and the panoramic dental X-ray. The NIST Tissue Engineering project characterizes scaffolds, the supports used to "grow" replacement tissues, and the interactions between scaffolds and cells. Other work develops sensors that measure biological properties and the interactions of cells and materials. 

NIST also participates in the Multi-Agency Tissue Engineering Science coordination group.

News and Updates

Making the DNA Melt Curve More Accurate

DNA is not only the blueprint of life; it has become the backbone for making tiny structures that can be inserted into the human body to diagnose and treat

Spotlight on N-STEP Graduates

NIST’s Science and Technology Entrepreneurship Program (N-STEP) was created by the company, TEDCO, whose mission is to “Enhance economic development growth

Projects and Programs

Tissue Engineering

Our goal is to develop reliable tools and standards for measuring the properties of cells, biomaterials, scaffolds and tissue-engineered constructs. As

Publications

Conformational gating, dynamics and allostery in human monoacylglycerol lipase

Author(s)
Sergiy Tyukhtenko, Girija Rajarshi, Ioannis L. Karageorgos, Nikolai Zvonok, Kiran Vemuri, Jeffrey W. Hudgens, Xiaoyu Ma, Mahmoud L. Nasr, Alexandros Makriyannis, Kyle W. Anderson, Jason J. Guo, Gerhard Wagner
Inhibition of human Monoacylglycerol Lipase (hMGL) offers a novel approach for treating neurological diseases. The design of inhibitors, targeting active

Awards