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Biomaterials

Overview

NIST's research examines the interactions among lab-made materials and biological systems, advancing the development of diagnostics and therapeutics, and improving the performance of biomaterials used in dentistry and regenerative medicine.

NIST's measurement methods and reference materials accelerate the development of lab-made materials that can help heal wounds or replace missing tissues, or be used to mimic human tissues for diagnostics or research. Our long partnership with the American Dental Association boasts advances such as the tooth-colored composites used to fill cavities and repair chipped teeth and the panoramic dental X-ray. The NIST Tissue Engineering project characterizes scaffolds, the supports used to "grow" replacement tissues, and the interactions between scaffolds and cells. Other work develops sensors that measure biological properties and the interactions of cells and materials. 

NIST also participates in the Multi-Agency Tissue Engineering Science coordination group.

News and Updates

The Ins and Outs of a NIST Patent

Electron or X-Ray Beam Lithography in Liquids Description These days, the fabrication of 2D and 3D structures out of liquid, biocompatible, hydrogel solutions

Projects and Programs

WG2 Biobanks and Bioresources

The ISO/TC 276/WG 2 will elaborate a package of International Standards in the Biobanks field including human, animal, plant and microorganism resources for

Tissue Engineering

Our goal is to develop reliable tools and standards for measuring the properties of cells, biomaterials, scaffolds and tissue-engineered constructs. As

Publications

Biobanking in the COVID-19 Era and Beyond: Part 2. A Set of Tool Implementation Case Studies

Author(s)
Clare M. Allocca, Emma Snapes, Monique Albert, Marianna J. Bledsoe, Marta Castelhano, Mieke DeWilde, Koh Furuta, Zisis Kozlakidis, Dunja Martin, Anabela Martins, Shannon McCall, Brent Schacter
The COVID-19 era has brought about a number of novel challenges for the global biobanking community. An array of diverse tools exists to support quality and

Conformational gating, dynamics and allostery in human monoacylglycerol lipase

Author(s)
Sergiy Tyukhtenko, Girija Rajarshi, Ioannis L. Karageorgos, Nikolai Zvonok, Kiran Vemuri, Jeffrey W. Hudgens, Xiaoyu Ma, Mahmoud L. Nasr, Alexandros Makriyannis, Kyle W. Anderson, Jason J. Guo, Gerhard Wagner
Inhibition of human Monoacylglycerol Lipase (hMGL) offers a novel approach for treating neurological diseases. The design of inhibitors, targeting active

Awards