Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Projects/Programs

Displaying 1 - 25 of 79

Advanced Microwave Radiometer Metrology

Ongoing
Using the NIST radiometer as a test bed, we studied the stability of temperature measurements for infrequent calibrations and developed stability metrics. We developed models to simulate output temperatures from the NIST radiometer, thus enabling the study of radiometer output without having to

Building Joint Sealant Service Life Prediction

Ongoing
The primary building sealant problem is that no method exists to provide high quality data for elucidating the relative importance of the k = 4 major weathering factors: X1: temperature, X2: humidity, X3: ultra-violet radiation, and X4: mechanical loading(and interactions) on the change in pre

Cement Characteristics by Direct Phase Assessment

Ongoing
DESCRIPTION: The major research goal is the accurate prediction of field performance metrics from accurate characterization of mineralogical composition and texture. Compounding characterization and prediction problems is the widespread reliance since the 1930's on the Bogue estimates of composition

Charpy Impact Machine Verification Program

Ongoing
The low cost and simple configuration of the test have made it a common requirement in codes for critical structures. However, the test is not useful if the variation in test results between laboratories is not tightly controlled. The control is accomplished by requiring the indirect verification of

Clutter Measurement

Ongoing
The Irregular Terrain Model (ITM) is a model for radio propagation that has been widely used for predicting the attenuation of a radio signal as a function of distance and the variability of the signal in time and in space. It was developed in the 1960 sand therefore does not fully utilize the

Comparison of Internet Congestion-Control Algorithms

Complex systems are generically characterized by a large number of factors and a large number of potential responses, hence statistical questions immediately present themselves as to 1. What should be measured? 2. What experiment design should be used to generate content-full data? 3. How should

A Comparison of WD-EPMA Heterogeneity Testing Procedures

Ongoing
X-ray stage mapping (XSM) can be used to determine the extent of heterogeneity on the micron scale though it is more time consuming and not as accurate as the more rigorous NIST random-point (RP) testing procedure. The objective of this work is to demonstrate the advantage of the latter procedure

Computational Biology: Comparison of Cell Image Segmentation Algorithms

Ongoing
The Problem: The initial project problem was to determine whether image analysis techniques existed (or could be developed by the ITL groups) which would assist in the automatic differentiation of the A10 and 3T3 cell lines. The larger problem at hand was to determine what factors (and interactions)

Computational Chemistry

Ongoing
Given the combinatorial possibilities for combining fundamental elements to create novel molecules, bench science experimentation is impractical as a wholesale means to discovery. By contrast, computational resources abound and thereby offer a possible alternative. However, this immense resource is

Computational Micromagnetics

Ongoing
Micromagnetics technologies constitute the foundation of computer storage devices. Exponential growth in the size of portable magnetic memories accompanied by decrease cost-per-byte is evidence of success in this technology. To sustain this growth engineers and scientists are increasingly using

Consistency Analysis and Uncertainty in ‘omic Data

Ongoing
‘Omics is increasingly moving out of the laboratory and towards use in industrial and commercial applications. For instance, in biomanufacturing, there is a need for quality control when developing biotherapeutics, which will almost certainly require a machine-learning classifier to separate

Critical Current Metrology

Ongoing
PML staff have completed the construction and testing of a variable-temperature and variable-strain, or unified, apparatus for measuring critical current. The apparatus combines world class capabilities in variable-temperature and variable-strain measurements and is expected to be the highest

Cyber Physical Systems and Internet of Things Program

Ongoing
Objective - Enable scalable, dependable design methods and reproducible performance measurement for effective and trustworthy (reliable, safe, secure, resilient and privacy-enhancing) cyber-physical systems and IoT, by means of new measurement science, advanced testing and assurance capabilities and

Design and Analysis of Key Comparisons

Ongoing
DESCRIPTION: With the recent signing of the Mutual Recognition Arrangement (MRA), National Metrology Institutes (NMI's) and Regional Metrology Organizations (RMO's) around the world have committed themselves to establishing the equivalence of their measurement standards. Currently, however, there is

Digital PCR

Ongoing
With appropriately validated assays, digital polymerase chain reaction (dPCR) determines the number of DNA targets (copies) per reaction partition, without the need for a standard curve. Reaction partitions can be in the form of fixed chambers in a microfluidic device, referred to as chamber digital

e-Statistics

Ongoing
DESCRIPTION: e-FITS is a web-based tool, currently available to NIST staff, used to perform the following tasks for over 100 probability distributions. Generate graphs of probability functions (probability density, cumulative distribution, inverse cumulative distribution, hazard, cumulative hazard

Experimental Evaluation of Large-Scale Parallel Measurement Systems

Ongoing
DESCRIPTION: An archetype among biological experiments is gene-by-gene determination of the expression difference between two groups of biological units. For each gene, the experiment yields a data set consisting of one or more expression values for each unit. Gene to gene, these data sets can be

External RNA Controls Consortium

Completed
While early gene expression measurements with DNA microarrays were groundbreaking in their ability to reveal biological activity, the results were irreconcilable and irreproducible. Industry leaders approached the National Institute of Standards and Technology (NIST) in 2003 for help with addressing

Fluid Phase Nuclear Magnetic Resonance (NMR) Spectroscopy

Ongoing
In-situ vapor-liquid equilibrium (VLE). We are applying vapor-phase NMR to measure VLE in-situ . We are currently applying this methodology to industrially important systems such as refrigerants and natural gas. The most widely used refrigerants have high global warming potential. Drop-in

Foundations of Measurement Science for Information Systems

Ongoing
According to the National Research Council report Network Science (2006), "[Despite] society's profound dependence on networks, fundamental knowledge about them is primitive. [G]lobal communication ... networks have quite advanced technological implementations but their behavior under stress still