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Chemistry

Analytical chemistry

Projects/Programs

Keyword

Organizational Unit

Quantum Bioimaging

Ongoing

The Biosystems and Biomaterials Division (BBD) is developing tools to take advantage of the quantum nature of light, enabling new biological measurements as

Rapid Drug Analysis and Research (RaDAR): Providing Near Real-Time Insight into the Illicit Drug Landscape

Ongoing

Drug overdose deaths continue to rise in the United States. Timely data on the drug landscape is difficult to obtain due to a constantly changing drug supply

Reference Materials and Standards for Fossil Fuels, Electric Utility Emissions, and Coal Combustion By-Products

Ongoing

National Institute of Standards and Technology (NIST) fossil fuel Standard Reference Materials (SRMs) continue to be in high demand by the petroleum industry

Relative Intensity Correction Standards for Fluorescence and Raman Spectroscopy

Ongoing

Luminescence measurements have become the methods of choice for new clinical and biochemical analyses due to their high selectivity and sensitivity. At the same

Renewable Energy and Fuels

Ongoing

Energy is one of the most critical problems facing the United States, with technical, economic, and public policy aspects. Our group develops state-of-the-art

Renewal of NIST Benchmark SRMs for Accurate Determinations of Trace Elements in Serum and Liver Tissues

Completed

The Centers for Disease Control and Prevention (CDC) collects data on elemental composition of human body fluids and tissues as part of major studies such as

Seabird Tissue Archival and Monitoring Project (STAMP)

Ongoing

In 1999, the U.S. Fish and Wildlife Service Alaska Maritime National Wildlife Refuge (USFWS-AMNWR), the U.S. Geological Survey Biological Resources Division

Secondary Ion Mass Spectrometry Ion Source Development

Ongoing

The use of cluster sources such as C 60 and argon gas cluster ion beams (Ar GCIB) allow for the analysis of the subsurface volume. It can also minimize the

Photograph of a packaged unit of SRM 2700 Hexavalent chromium in Contaminated Soil (low Level)

Standard Reference Materials for Hexavalent Chromium in Contaminated Soil

Completed

Significant environmental remediation efforts are being conducted to address the hazards posed by the long-term terrestrial disposal of hexavalent chromium in

Standard Solution SRMs Provide Traceability for Millions of Measurements

Ongoing

For decades, NIST has provided the SRM 3100 series single-element standard solutions. The certified values are traceable to the International System of Units

State-resolved Spectroscopy of Biomolecules

Ongoing

Sensitive and fully state resolved spectroscopic methods in the terahertz (THz) and ultraviolet (UV) regions are being developed to investigate the structure

Study of Microheterogeneity in Solid Reference Materials

Ongoing

Microbeam X-ray fluorescence (µXRF) has been used nondestructively to investigate elemental heterogeneity by constructing two-dimensional maps of elemental

Photograph of a toy race car, toy monster truck with snail face, and sagging toy bridge.

Support of the Consumer Product Safety Improvement Act (CPSIA) of 2008 - Lead in Paint on Toys

Ongoing

After enactment of the CPSIA, a collaboration was established between the Consumer Product Safety Commission (CPSC) and NIST for the purpose of developing tools

Support of Industry Compliance with the EU Directive on Restriction of Certain Hazardous Substances (RoHS)

Ongoing

The Chemical Sciences Division is involved in development of standards and reference materials for restricted hazardous substances through participation in

Surface Desorption Ambient Mass Spectrometry

Ongoing

Surface desorption ambient mass spectrometry enables direct solid surface interrogation for sampling and ionization of trace analytes. This project encompasses

Tandem Mass Spectral Library

Ongoing

The National Institute of Standards and Technology is responsible for providing an evaluated tandem mass spectral library for reliable compound identification

Schematic figure illustrating the principle of operation of a mass spectrometer, showing deflection of ions based on mass.

Theoretical Mass Spectrometry

Ongoing

Mass spectrometry is an important technique in analytical chemistry, essential in areas including drug development, criminal and agricultural forensics

Thermal Desorption Ambient Mass Spectrometry

Ongoing

Thermal desorption ambient mass spectrometry decouples analyte desorption and ionization. Here, analytes are thermally desorbed directly from a primary surface

Time-of-Flight Secondary Ion Mass Spectrometry

Ongoing

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) employs a pulsed primary ion beam and a time-of-flight mass analyzer for the detection of molecular

Traceability in Molecular Spectrophotometry

Ongoing

Standard Reference Materials® ( SRMs®) and commercially produced, NIST-traceable materials for UV/visible/NIR spectrophotometry are transfer standards that

Photography of gas cylinder storage facility with cylinders stored horizontally in movable cabinets.

Traceable Calibration Gases: SRMs, NTRMs, and Protocol Gases

Ongoing

The Gas Sensing Metrology Group in the Chemical Sciences Division is tasked with providing traceability in gas analysis for the U.S. This group works with

Online video tutorials education button in Laptop notebook computer screen. Play lesson concept. Vector illustration

Tutorials in Analytical Chemistry

Ongoing

The following videos and corresponding narrated PowerPoint presentations are provided for training and education in chemical metrology. Each presentation

Series of MRI images labeled A to E showing different views of brain tissue, some with gadolinium highlighted in blue against a purple background.

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Ongoing

Gadolinium-Based Contrast Agents (GBCA) are intravenous drugs used in diagnostic imaging procedures to enhance the quality of magnetic resonance imaging (MRI)

Vapor Sampling in the Field

Ongoing

We develop and deploy portable vapor sampling instruments to collect detailed chemical information in the field, in sampling situations where the laboratory is

Vapor Sampling to Support Public Safety and Forensics

Ongoing

We develop and evaluate dynamic headspace sampling methods to capture and concentrate vapors from single components (solid or liquid) to determine vapor

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---Quantum Measurement Division
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