Analytical chemistry

News and Updates

Picture of jars containing reference materials 8256, 8257, 8258, and 8259: Wild caught and aquacultured shrimp and salmon

Four NIST Reference Materials Help Authenticate Shrimp and Salmon

July 28, 2022

Four reference materials from NIST will help the U.S. Food and Drug Administration and Customs and Border Protection agencies assess whether imported salmon and

Two open glass containers hold powder, one brown and one wite, with half-filled plastic scoops next to each.

NIST Tree Nut Reference Materials Support Food Allergen Testing

June 6, 2022

Researchers from NIST have developed hazelnut and almond flour reference materials that will help ensure accurate and consistent results for industry test kits.

Illustration shows coffee cup with magnified section showing plastic particles.

NIST Study Shows Everyday Plastic Products Release Trillions of Microscopic Particles Into Water

April 20, 2022

Researchers analyzed widely used consumer products to better understand these microscopic plastics.

Projects and Programs

NCNR DAC and CCUS efforts

Ongoing

Overview Capture of carbon dioxide from the air (direct air capture; DAC) combined with energy efficiency and carbon capture, utilization and storage (CCUS)

NIST Tools for Cannabis Laboratory Quality Assurance

Ongoing

NIST is developing an integrated measurement services program for forensic and Cannabis (hemp and marijuana) laboratories to help ensure the quality of routine

Far-infrared Spectroscopy of Biomolecules (Archived)

Completed

Far-infrared (or terahertz/THz, ca. 25 to 300 micron wavelength) femtosecond pulsed laser and Fourier-transform infrared methods are employed to measure

PTIR combines the spatial resolution of AFM with the specificity of absorption spectroscopy

Nano-Chemical Imaging and -Spectroscopy (IR, nIR, VIS)

Ongoing

Conventional techniques for analyzing chemical composition, such as infrared (IR) microscopy often miss critically important nanoscale details. To overcome this

Publications

Mass Spectral Library Methods for Analysis of Site-Specific N-Glycosylation: Application to Human Milk Proteins

September 16, 2022

Author(s)

Concepcion Remoroza, Meghan Burke Harris, Xiaoyu (Sara) Yang, Sergey Sheetlin, Yuri Mirokhin, Sanford Markey, Dmitrii V. Tchekhovskoi, Stephen E. Stein

We present a mass-spectral library-based method for analyzing site-specific N-linked protein glycosylation. Its operation and utility are illustrated by

Levels and profiles of perfluorinated alkyl acids in liver tissues of birds with different habitat types and trophic levels from an urbanized coastal region of South Korea

August 1, 2022

Author(s)

Sang Hee Hong, Jessica L. Reiner, Mi Jang, Stacy Schuur, Gi Myung Han, John Kucklick, Won Joon Shim

Contamination status and characteristics of perfluorinated alkyl acids (PFAAs) including perfluorinated carboxylic acids (PFCAs) and perfluorinated sulfonic

Broadband Dielectric Spectroscopic Detection of Ethanol: A Side-by-Side Comparison of ZnO and HKUST-1 MOFs as Sensing Media

June 25, 2022

Author(s)

Papa Amoah, zeinab Hassan, Pengtao Lin, Engelbert Redel, Helmut Baumgart, Yaw S. Obeng

We leverage thermal- and chemical-induced changes in microwave propagation characteristics (i.e., S-parameters) to compare ZnO and surface anchored metal

Chromatography at -30 °C for Reduced Back-Exchange, Reduced Carryover, and Improved Dynamic Range for Hydrogen-Deuterium Exchange Mass Spectrometry

June 22, 2022

Author(s)

Kyle Anderson, Jeffrey W. Hudgens

For hydrogen-deuterium exchange mass spectrometry (HDX-MS) to have an increased role in quality control of biopharmaceuticals, H for D back-exchange occurring

Software

NIST Mass and Fragment Calculator Software

January 31, 2019

The NIST Mass and Fragment Calculator is a program written in Visual Basic which calculates the mass of an input peptide or protein sequence along with m/z ions

NIST DTSA-II

February 1, 2018

NIST DTSA-II builds on the best available algorithms in the literature to simulate, quantify and plan energy dispersive x-ray analysis measurements.

JB95 Spectral fitting program

February 19, 2016

A graphical user interface program, JB95, based on a Windows 95© API platform has been written in the C programming language to aid in the analysis of complex

Custom Lifetime Imaging Platform (CLIP)

CLIP is an analysis program for fluorescence lifetime images. It provides the user with the ability to fit or calculate the phasor plots for lifetime decays

Tools and Instruments

Focused Ion Beam (Helios 660)

The Helios 660 NanoLab(HNL660) is a Focused Ion Beam Scanning Electron Microscope equipped with spectroscopic detectors to allow elemental and phase

Focused Ion Beam

The Nova NanoLab 600 (NNL600) is a Focused Ion Beam Scanning Electron Microscope equipped with spectroscopic detectors to allow elemental and phase measurements

X-Ray Diffractometer

The Bruker D8 defractometer is a general purpose X-ray diffraction system. The instrument features easy reconfiguration of the X-ray optics for a variety of

Automated Scanning Electron Microscope

The ASPEX Personal SEM (PSEM) is a tungsten filament scanning electron microscope optimized for automated particle analysis. The system was designed with

Analytical chemistry

News and Updates

Four NIST Reference Materials Help Authenticate Shrimp and Salmon

NIST Tree Nut Reference Materials Support Food Allergen Testing

NIST Study Shows Everyday Plastic Products Release Trillions of Microscopic Particles Into Water

Projects and Programs

NCNR DAC and CCUS efforts

NIST Tools for Cannabis Laboratory Quality Assurance

Far-infrared Spectroscopy of Biomolecules (Archived)

Nano-Chemical Imaging and -Spectroscopy (IR, nIR, VIS)

Publications

Mass Spectral Library Methods for Analysis of Site-Specific N-Glycosylation: Application to Human Milk Proteins

Levels and profiles of perfluorinated alkyl acids in liver tissues of birds with different habitat types and trophic levels from an urbanized coastal region of South Korea

Broadband Dielectric Spectroscopic Detection of Ethanol: A Side-by-Side Comparison of ZnO and HKUST-1 MOFs as Sensing Media

Chromatography at -30 °C for Reduced Back-Exchange, Reduced Carryover, and Improved Dynamic Range for Hydrogen-Deuterium Exchange Mass Spectrometry

Software

NIST Mass and Fragment Calculator Software

NIST DTSA-II

JB95 Spectral fitting program

Custom Lifetime Imaging Platform (CLIP)

Tools and Instruments

Focused Ion Beam (Helios 660)

Focused Ion Beam

X-Ray Diffractometer

Automated Scanning Electron Microscope

Awards

Amanda Moors Recognized for NIST Biorepository Work

Lane Sander Honored by American Chemical Society

David Long Honored with PECASE

Dr. Tara Lovestead receives highest US government honor for young investigators