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Material Measurement Laboratory

Biomolecular Measurement Division

Projects/Programs

Displaying 1 - 25 of 35
Bioman lifecycle

Biomanufacturing Initiative

Protein drugs are the top selling pharmaceuticals worldwide, a hundred billion dollar industry, but also the fastest growing category of health care costs. The

Digital PCR

Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR platforms for

DNA Biometrics

There is ongoing interest in utilizing DNA typing methods for biometric purposes. Forensic DNA typing using STR markers has been performed in the criminal
A table containing the 13 N-linked glycan structures to be included in NIST SRM 3655

Glycan Standard Reference Materials

A glycan-based Standard Reference Material (SRM 3655) is being developed at NIST to support the biomanufacturing and protein therapeutics communities. The SRM
Deuterium uptake in NISTmAb Fab Fragment

HDX-MS for Biopharmaceutical Analysis

This project applies hydrogen/deuterium exchange mass spectrometry (HDX-MS) for determining the dynamical structure of therapeutic antibodies, glycoproteins

Nanocalorimetry

Nanocalorimetry using micromachined devices has the capability to provide quantitative data to support the development of advanced metal silicide metallizations