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Projects/Programs

Displaying 151 - 175 of 568

Electronic Material Characterization

Ongoing
Manufacturing optimized devices that incorporate newly-emerging materials requires predictable performance throughout device lifetimes. Unexpected degradation in device performance, sometimes leading to failure, is often traceable to poor material reliability. Reliability is rooted in the stability

Electronic Structure and Dynamics in Quantum Materials

Ongoing
Photoemission-based methods that interrogate solid state electronic structure have played a pivotal role in identifying and understanding key features of emerging materials. Band structure information from Angle-Resolved PhotoEmission Spectroscopy (ARPES) provided the first evidence for the d-wave

Electron-Solid Interactions

Ongoing
A measuring instrument produces a signal that depends upon the value of the measurand. The value and its uncertainty are inferred from the signal by using a model of their relationship. Erroneous models lead to erroneous inference. The accuracy of SEM (scanning electron microscopy) is limited by

Energy Storage & Delivery

Completed
Our program will address key measurement issues related to structure and dynamics of important classes of PEM materials, including emerging systems like block copolymers, polymer blends, and candidate materials proposed by industry leaders like GM. We are developing advanced methods that illuminate

Engineering Biology Metrics and Technical Standards for the Global Bioeconomy

Ongoing
Stakeholders from the Americas, Asia and Australia, and Europe and Africa, came together through a series of regional workshops in Washington D.C., Singapore, and Brussels, respectively, to identify specific areas for development, both technical and non-technical towards continued scale-up and economic growth across the bioeconomy.

Engineering Living Measurement Systems to Sense PFAS

Ongoing
Per- and polyfluoroalkyl substances, PFAS, are thermodynamically stable organic fluorinated chemicals that are resistant to traditional degradation pathways leading to concern for bioaccumulation. These compounds originate from several industrial manufacturing processes and are found in soil systems

Engineering of G Protein-Coupled Receptors

Ongoing
A trait of all life is the ability to sense and respond to changing environments, and the largest family of eukaryotic proteins that sense and respond to extracellular signals are called G Protein-Coupled Receptors (GPCRs). In humans, over 800 GPCRs detect a wide range of biological and chemical

Environmental Leaching of Nanoparticles from Consumer Products

Ongoing
New nanotechnology-based consumer products are currently entering the market at a rate of 3 or 4 per week, and it is estimated that $2.6 trillion in manufactured goods will contain nanotechnology by 2014. Unfortunately, the overall safety of short- and long-term exposure to nanoparticles and the

Environmental Metrology Measurement Assistant (EMMA)

Ongoing
Quantification of environmental metrology data can be complex at the level on which NIST operates. Projects often include dozens of samples from multiple matrices and can target well over 300 analytes of vastly different chemical properties, each of which must be individually assessed. Quality

ERCC 2.0: Developing a New Suite of RNA Controls

Completed
Requested RNA Control products include: Transcript isoforms; New and improved messenger RNA mimics and mixture formulations; microRNA and other small RNA molecules; and Cancer fusion transcripts. ERCC technical working groups are developing design specifications, RNA control products, and analysis

EUV Scatterometry

Ongoing
To measure and inspect the smallest printed features on an IC chip, researchers and manufacturers use a combination of electron scanning modalities (i.e., transmission electron and scanning electron microscopies) and an optical method, scatterometry. Industrially, the most common modality for

Evaluating Measurement Quality of Microfluidic Cell-based Assays

Completed
Impact and Customers Our work establishes metrics for measurement quality and reproducibility for cell-based assays within microfluidic devices. Many novel microfluidic devices are being created that permit new measurements or enable new biological functions to be tested; however, characterizations

Evaluation of 2D and WBG Material Quality Toward Device Reliability

Ongoing
Two-dimensional (2D) and wide band gap (WBG) materials are some of the latest materials classes having the potential to be transformative because of their high carrier mobilities, tunable bandgap, and atomic-scale film thicknesses. Unexpected degradation and failure in device performance is often

Explosives Decomposition Chemistry

Completed
Intended Impact Computational modeling and simulation will help in the invention of new explosives, the design of compounded mixtures of existing materials, and the engineering of delivered systems such as military ordnance. Objective Detailed chemistry is a necessary part of computational

External RNA Controls Consortium

Completed
While early gene expression measurements with DNA microarrays were groundbreaking in their ability to reveal biological activity, the results were irreconcilable and irreproducible. Industry leaders approached the National Institute of Standards and Technology (NIST) in 2003 for help with addressing

Extreme Atom Probe Tomography

Ongoing
Sub-nanometer-resolved 3-D chemical mapping of any atom in any solid continues to be an imperative goal of materials research. If reduced to practice, it would have profound scientific, engineering, and economic impacts on U.S. industries collectively worth hundreds of billions of dollars. Such

Facilitating the Development of Modular Data Models in Materials Science

Ongoing
Development of Data Models This project is convening experts with the goal of developing foundational data types and domain-specific data models to address common modeling, synthesis and measurement techniques. The existence of such data models will facilitate the adoption of the Materials Data

Fatigue in Silicon

Ongoing
It has long been thought that bulk silicon is immune to fatigue. We present contrary evidence by demonstrating severe fatigue in macroscale specimens. Cracks are produced during cyclic loading of monocrystalline silicon plates with a 3 mm radius sphere indenter mounted onto a universal testing

Fatty Acids in Human Serum and Plasma Quality Assurance Program (FAQAP)

Completed
Interlaboratory comparison studies of the FAQAP focused on the measurement of 24 fatty acids in selected serum and plasma matrices. Frozen or freeze-dried serum or plasma samples were sent to laboratories for analysis together with control materials. Results were returned to NIST for data evaluation
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