U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Material Measurement Laboratory

Projects/Programs

Displaying 101 - 125 of 577
blue crystal

Crystallographic Databases

Ongoing
Impact and Customers Materials with new or improved properties are continually being developed to meet demands for increased functionality of components and devices at decreased costs. Examples of multi-million dollar industries driven by materials advances are solid-state lighting (GaN-based...
DARPA IV&V Workflow

DARPA Friend or Foe (FoF) – Independent Verification and Validation (IV&V)

Completed
Vision Validate new measurement platforms for identifying commensal (friend) and pathogenic (foe) microorganisms Goal Provide well-characterized, microbial community reference materials of increasing complexity Approach Start with well-characterized pure cultures and scale up to complex consortia in...

AI/ML for Data Extraction and Uncertainty Predictions

Ongoing
The Material Measurement Lab at NIST employs artificial intelligence for the prediction and discovery of materials characteristics. Our applications of artificial intelligence (AI) accelerate materials research as well as help the community learn about AI's capabilities and gain confidence in...
Big data analysis report on 3D effects.AI technology generated image

Data Tools for Environmental Metrology

Ongoing
A recent addition to operations in the NIST Biorepository, we seek out places where NIST scientists get bogged down by the complexity of their data. Research at NIST can generated some of the most complex data in the world, at times requiring six months or more of processing to get to the data...

Decontamination of Biological Threats in Water Supplies

Completed
The outcome of the project was to provide the EPA with a technical resource document that could be used to guide emergency responders and for longer-term microbial decontamination of building water systems. This project was done in collaboration with the Building and Fire Research Laboratory (BFRL)...

Deducing Prior Material Deformation from Simple Mechanics

Ongoing
Process-structure-property linkages suggest an opportunity to deduce processing from behavior. Simple imaging experiments provide rich sources of data. Can we deduce prior deformation? Scheme: Thin film plasticity Deform to some reference strain Unload Deform to test strain, image Deduce...

Determinations of Boron Deposit Quality by Neutron Depth Profiling

Ongoing
Neutrons are not easily detected with high resolution and good efficiency. Consequently, high-quality neutron detectors remain a challenge to manufacture. A few nuclides such as He-3, Boron-10, and Li-6 are commonly used to convert impinging neutrons into an electrical pulse that post-processing...

Developing a Materials Innovation Infrastructure

Completed
Phase Field Community Hub ( PFHub) and Benchmarks The Phase Field Community Hub provides a framework that supports phase field practitioners and code developers participating in an effort to improve quality assurance for phase field codes. The main thrust of this effort is the generation of a set of...

Development of Biomarker-based Systems for Cancer Detection and Therapy

Completed
Intended impact Although significant progress has been made in both the understanding and treatment of cancer during the last thirty years, it remains the second leading cause of death in the US. The cancer community has set a goal to eliminate cancer-related suffering and death by 2015. To achieve...

Development of Enhanced mRNA Amplification Using Microfluidics

Completed
Intended Impact Tissue samples frequently contain multiple cell types. New methods (e.g. laser capture microdissection) enable the segregation of small quantities of individual cells and cell types, but the current methods to analyze global gene expression do not provide highly efficient profiling...

Development of the NIST Prototype Advanced Biometrology Laboratory

Ongoing
Currently, NIST is investing in a new type of metrology laboratory that is focused on the unique reference material and high quality assay protocols that are needed in the regenerative medicine and biotechnology communities. The laboratory design is centered on automation that can set up 1000’s of...
Photograph of SRM 3950 Vitamin B6 in Frozen Human Serum with labeled box and frosty capped bottles containing level 1 and level 2.

Development of Serum-Based SRMs to Assess Nutritional Status

Ongoing
Vitamin deficiencies are generally considered rare in the U.S., but a growing body of evidence suggests that certain deficiencies may be more prevalent than originally thought. For example, it has been estimated that 10 % to 15 % of adults over the age of sixty are affected by vitamin B 12...
Photograph of SRM 2669 Arsenic Species in Frozen Human Urine, with vials and desiccant packs, and labeled mylar bag.

Development of SRM 2669 for Accurate Assessment of Arsenic Exposure

Ongoing
Arsenic exposure in the U.S. population is an important part of the NHANES program conducted by CDC because dietary exposure to arsenic can cause serious health effects. A major challenge in the arsenic exposure assessment is that arsenic exists as various species in nature, and the toxicity of...
GC-ICP-MS Chromatogram

Development of SRM 955c Toxic Elements in Caprine Blood

Completed
Intended Impact Over the last three decades, NIST, with support from the Centers for Disease Control (CDC), and in conjunction with the New York State Department of Health’s (NYSDOH) Wadsworth Center, has produced a number of frozen whole blood certified reference materials containing endogenous...
Was this page helpful?