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Physics

Biological Physics

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Displaying 76 - 100 of 377

Transparent High-Frequency Ultrasonic Transducer for Photoacoustic Microscopy Application

September 1, 2020
Author(s)
Jeeseong Hwang, Christopher S. Yung, Ruimin Chen, Yun He, Junhui Shi, Lihong Wang, Qifa Zhou
We report the development of an optically transparent high-frequency ultrasonic transducer using lithium niobate single-crystal and indium-tin-oxide electrodes with up to 90 % optical transmission in the visible to near infrared spectrum. The center

The C-terminus and Third Cytoplasmic Loop Cooperatively Activate Mouse Melanopsin Phototransduction

July 21, 2020
Author(s)
Juan C. Valdez-Lopez, Stephen T. Petr, Matthew P. Donohue, Robin J. Bailey, Meheret Gebreeziabher, Evan G. Cameron, Julia B. Wolf, Veronika Szalai, Phyllis R. Robinson
Melanopsin, an atypical vertebrate visual pigment, mediates non-image forming light responses including circadian photoentrainment and pupillary light reflexes, and contrast detection for image formation. Melanopsin-expressing intrinsically photosensitive

Electromagnetics for Quantitative Magnetic Resonance Imaging

July 20, 2020
Author(s)
Stephen E. Russek, Karl F. Stupic, Joshua R. Biller, Michael A. Boss, Kathryn E. Keenan, Elizabeth Mirowski
Magnetic Resonance Imaging (MRI) is based on radio frequency (RF) interrogation of the human body at frequencies between 40 MHz to 300 MHz. An RF transmitter excites proton spin precession and then, in a manner analogous to an RF ID tag, the proton’s

Ion transport across solid-state ion channels perturbed by directed strain

April 28, 2020
Author(s)
Alex Smolyanitsky, Alta Y. Fang, Andrei F. Kazakov, Eugene Paulechka
We combine quantum-chemical calculations and molecular dynamics simulations to consider aqueous ion flow across non-axisymmetric nanopores in monolayer graphene and MoS2. When the pore-containing membrane is subject to uniaxial tensile strains applied in

Rapid, quantitative therapeutic screening for Alzheimer's enzymes enabled by optimal signal transduction with transistors

April 14, 2020
Author(s)
Son T. Le, Michelle A. Morris, Antonio Cardone, Nicholas B. Guros, Jeffery B. Klauda, Brent A. Sperling, Curt A. Richter, Harish C. Pant, Arvind Balijepalli
We show that commercially sourced n-channel silicon field-effect transistors (nFETs) operating under closed-loop control achieve a resolution of (7.2+/-0.3)x10-3 pH units with a bandwidth of 10 Hz. The results represent an 3-fold improvement in performance