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Breast-conserving surgery, or lumpectomy, is a treatment for early-stage breast cancer. It’s important for surgeons to remove enough tissue around the tumor to
“Only connect” is the most famous line in the British novelist E. M. Forster’s writings. Forster was urging the readers of his book Howard’s End to make
Researchers at the National Institute of Standards and Technology (NIST) and colleagues have developed a novel, anatomically accurate reference model of the
This project aims to develop light-scattering microscopy methods for rapid, multi-attribute characterization of gene therapy particles at the single particle level. Emerging gene therapy treatments use gene delivery particles, such as viral vectors and non-viral carriers, to cure intractable
Cellular remodeling of their neighboring environment, extracellular matrix (ECM), is an important biological process from development biology, to wound healing, to diseases and cancers – this is a challenging process to measure and quantify. Surface plasmon resonance imaging (SPRI) has been
Cell-free expression systems are poised to advance the US bioeconomy and play a key role in ensuring US manufacturing resilience. NIST has several, on-going projects in its growing portfolio to promote reproducibility, new measurement methods, and best practices and standards in cell-free expression
Light microscopy is unparalleled as a quantitative technique for studying cell biology, but assuring that the results of measurements and analyses are accurate, repeatable and sharable is challenging. Here we provide information on reference materials, protocols and approaches for evaluating the
Xiaojun Wei, Dumei Ma, Junlin Ou, Ge Song, Jiawei Guo, Joseph Robertson, Yi Wang, Qian Wang, Chang Liu
Nanopores have demonstrated remarkable sensitivity as biosensors, enabling the sequencing of DNA and RNA at the single-molecule level. The rapid progress in
Enumeration of bacterial colonies on an agar plate is simple in concept, but automated colony counting is difficult due to variations in colony color, size