Biological physics

News and Updates

A new twist on measuring spin: NIST Develops Microresonator to Study Electron Spin in Small Volumes

November 17, 2020

Researchers at the National Institute of Standards and Technology (NIST) have developed a device to detect a quantum property of electrons, known as spin, in

Making the DNA Melt Curve More Accurate

August 18, 2020

DNA is not only the blueprint of life; it has become the backbone for making tiny structures that can be inserted into the human body to diagnose and treat

Getting a closer look at living cells and batteries: a little bit of graphene goes a long way

March 6, 2020

Researchers at NIST have devised a way to eliminate a long-standing problem affecting our understanding of both living cells and batteries. When a solid and an

Probing the Origin of Alzheimer’s . . . with Transistors

August 7, 2019

A prime suspect in the onset of Alzheimer’s and Parkinson’s diseases is a normally benign enzyme that is essential to proper development of the nervous system

Projects and Programs

Optical medical imaging

The Optical Medical Imaging project was established to advance the application of optical imaging in surgical, clinical, and medical practices. Our goal is to

Dosimetry Standardization for Radiobiology - ARCHIVE

A program for the development of dosimetry standards for radiobiology was launched through a highly successful workshop. The NIAID/NCI/NIST-sponsored workshop

Label-free imaging of cells and their extracellular matrix by SPR imaging

Metrology For Cell-Free Expression Systems

The Cellular Engineering Group works to provide measurement assurance for more reproducible and comparable cell-free expression systems.

Publications

Transparent High-Frequency Ultrasonic Transducer for Photoacoustic Microscopy Application

September 1, 2020

Author(s)

Jeeseong Hwang, Christopher S. Yung, Ruimin Chen, Yun He, Junhui Shi, Lihong Wang, Qifa Zhou

We report the development of an optically transparent high-frequency ultrasonic transducer using lithium niobate single-crystal and indium-tin-oxide electrodes

Construction of a Dual Protease Column, Subzero (-30 °C) Chromatography System and Multi-channel Precision Temperature Controller for Hydrogen-Deuterium Exchange Mass Spectrometry

August 12, 2020

Author(s)

Jeffrey W. Hudgens

This tutorial provides mechanical drawings, electrical schematics, parts lists, stereolithography (STL) files for producing three-dimensional (3D)-printed parts

The C-terminus and Third Cytoplasmic Loop Cooperatively Activate Mouse Melanopsin Phototransduction

July 21, 2020

Author(s)

Juan C. Valdez-Lopez, Stephen T. Petr, Matthew P. Donohue, Robin J. Bailey, Meheret Gebreeziabher, Evan G. Cameron, Julia B. Wolf, Veronika A. Szalai, Phyllis R. Robinson

Melanopsin, an atypical vertebrate visual pigment, mediates non-image forming light responses including circadian photoentrainment and pupillary light reflexes

Electromagnetics for Quantitative Magnetic Resonance Imaging

July 20, 2020

Author(s)

Stephen E. Russek, Karl F. Stupic, Joshua R. Biller, Michael A. Boss, Kathryn E. Keenan, Elizabeth Mirowski

Magnetic Resonance Imaging (MRI) is based on radio frequency (RF) interrogation of the human body at frequencies between 40 MHz to 300 MHz. An RF transmitter

Software

NIST's Integrated Colony Enumerator (NICE)

August 11, 2010

Enumeration of bacterial colonies on an agar plate is simple in concept, but automated colony counting is difficult due to variations in colony color, size