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Displaying 1151 - 1175 of 1280

Detection of p53 Gene Mutation: Analysis by Single-Strand Conformation Polymorphism and Cleavase Fragment Length Polymorphism

June 1, 1999
Author(s)
C D. O'Connell, Donald H. Atha, M C. Oldenburg, J Tian, M Siebert, D Handrow, K Grooms, L Heisler, M de Arruda
We have generated a collection of clones containing single point mutations within the exon 5-9 hot spot regions of the p53 gene by using polymerase chain reaction (PCR) to amplify select regions of the gene from characterized cell lines. These clones were

Dynamic Partitioning of Neutral Polymers into a Single Ion Channel

June 1, 1999
Author(s)
S. M. Bezrukov, John J. Kasianowicz
Polymers partitioning into highly confined spaces can be studied using single nanometer-scale pores formed by protein ion channels. The ionic conductance of a channel depends on the state of occupancy of the pore by polymer and serves as a measure of

Electronic Structure and Spectra of Oxovanadium Silicate

January 11, 1999
Author(s)
Morris Krauss
The electronic structure and spectroscopy of the oxovanadium catalytic center on a silica surface is modeled with the molecule OV(OSIH 3)3. Excited electronic states are examined at optimized geometries for the ground singlet and triplet states. For both

Spectroscopy of 2-aminopurine: An MCSCF Study

December 1, 1998
Author(s)
E L. Rachofsky, J B. Ross, Morris Krauss, R Osman
2-aminopurine (2AP) is a highly fluorescent isomer of adenine that can be incorporated into DNA as a probe of structure, dynamics, and protein-DNA interactions. Interpretation of the fluorescence of 2AP in DNA requires a model of the electronic structure
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