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Donald H. Atha, H M. Wenz, H MoreHead, J Tian, C D. O'Connell
We have analyzed five p53 single point mutations by single strand conformation polymorphism using capillary electrophoresis (CE-SSCP) and have compared these measurements to measurements obtained by slab gel electrophoresis (SG-SSCP). PCR primers were used
C D. O'Connell, J Tian, A Juhasz, H M. Wenz, Donald H. Atha
We have amplified by polymerase chain reaction (PCR) a 2.0 kbp region of the p53 gene containing exons 5-9 from seven cell lines reported in the literature to contain the majority of mutations reported for this gene. Sequence analysis of these products
1.1 Reactions of Free Radicals with DNAFree radicals produce a number of lesions in DNA such as base lesions, sugar lesions, DNA-protein cross-links, single-strand breaks, double-strand breaks and abasic sites by a variety of mechanisms (Teoule and Cadet