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Bioscience

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Displaying 1101 - 1125 of 1261

The Effect of an Oxidized Gold Substrate on Alkanethiol Self-Assembly

June 1, 2000
Author(s)
John T. Woodward IV, Marlon L. Walker, Curtis W. Meuse, David J. Vanderah, G Poirier, Anne L. Plant
UV cleaned gold substrates incubated in solutions of alkanethiol show islands on the monolayer surface when imaged with non-contact atomic force microscopy (AFM). The height of the islands above the monolayer is approximately twice the height of the

Effective Fragment Potentials and the Enzyme Active Site

May 1, 2000
Author(s)
S E. Worthington, Morris Krauss
Optimization of the binding conformation of a substrate in an enzyme active site using ab initio quantum chemistry methods are intractable since the active site comprises several hundred atoms. However, the active site can be decomposed into an active and

Differential Surface Stress of a Tin Oxide Electrode

April 1, 2000
Author(s)
Gintaras Valincius, Vytautas Reipa
Differential surface stress measurements performed using estance technique and simultaneous measurements of the differential capacitance provide experimental evidence for deviation of n-tin oxide electrode's properties from the electrocapillary

Human Mitochondrial Genetics

January 1, 2000
Author(s)
L A. Tully, Barbara C. Levin
The field of human mitochondrial genetics has advanced way beyond where the Human Genome Project hopes to be by the year 2003, the projected year for completing the sequence of the entire human nuclear DNA genome. Not only has the mitochondrial DNA (mtDNA)

Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules

December 1, 1999
Author(s)
M Akeson, D Branton, John J. Kasianowicz, E Brandin, D W. Deamer
Single molecules of DNA or RNA can be detected as they are driven through a single alpha-hemolysin channel by an applied electric field. During translocation, nucleotides within the polynucleotide must pass through the channel pore in sequential single
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