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Projects/Programs

Keyword

Organizational Unit

CCQM Activities in the Inorganic Analysis Working Group and the Electrochemical Analysis Working Group

Ongoing

Together with other NMIs participating in the Inorganic and Electrochemical Analysis Working Groups (IAWG and EAWG) the work is intended to provide an open, transparent and comprehensive scheme to give users reliable quantitative information on the comparability of national metrology services and to

CCQM Activities in the Organic Analysis Working Group

Ongoing

The results from these studies will be used to demonstrate the capabilities of participating NMIs for their similar measurement services, and eventually benchmark the appropriate  Calibration and Measurement Capabilities (CMCs) that summarizes this capability.  NIST CMCs that directly support SI

Celebrating A Successful 2024 Regional Measurement Assurance Program (RMAP)

Ongoing

Within each region, metrologists from the state laboratories, together with representatives from the various metrology industries, gather each year to network, share experiences, and receive training in a variety of metrology topics. These meetings are unique in that they not only bring together the

Cell Counting for Cell Therapies

Ongoing

Recent Publications and Resources for Cell Counting and Related Measurements Tools NOW AVAILABLE : COMET (Counting Method Evaluation Tool) , A Shiny Application that executes the statistical analysis and reporting outlined in ISO 20391-2:2019 https://cell-counting.shinyapps.io/COMET/ Standards ISO

Samples for Cell free DNA Methylation Measurements

Cell free DNA Methylation Measurements: Invitation to Participate in an Interlaboratory Testing Program Evaluating Methylated Cell free DNA Test Materials

Ongoing

For this study, one set of materials was prepared by LGC Clinical Diagnostics and contains non-methylated cfDNA based on whole genome amplification, and methylated cfDNA by in vitro methylation. Both duplicate the size range of cfDNA. The other set of materials was prepared at NIST and was made with

Cell Line Authentication

Ongoing

Cell Line Authentication – The scientific community has responded to the misidentification of human cell lines with validated methods to authenticate these cells; however, there are few assays available for nonhuman cell line identification. We have developed multiplex polymerase chain reaction (PCR

Cell Viability for Advanced Therapies

Ongoing

In the Biosystems and Biomaterials Division at NIST, we have established several technical programs to support the development and implementation of cell viability assays in advanced therapies. These programs address key needs in cell viability assay development including selection and development

Cell-based Assay for Mechanistically-based Prediction of Cytoxicity

Ongoing

Ricin is a type 2 ribosome inactivating protein (RIP) belonging to the A-B family of toxins and is of particular interest because of its potential use as a biological weapon and the dearth of rapid and sensitive assays that could assist detection and decontamination. The ricin toxin inhibits protein

Cement Characteristics by Direct Phase Assessment

Ongoing

DESCRIPTION: The major research goal is the accurate prediction of field performance metrics from accurate characterization of mineralogical composition and texture. Compounding characterization and prediction problems is the widespread reliance since the 1930's on the Bogue estimates of composition

Certification of a Standard Reference Material for Cytomegalovirus (CMV)

Ongoing

The goal of this project is to provide a SI-traceable reference material for use by calibrant and reagent manufacturers in production of their own calibrants and standards. Clinical laboratories with in-house methods would be able to use the reference material for production of their own quality

Certification of Standard Reference Material 2393 for the CAG repeats of Huntington Disease

Ongoing

This Standard Reference Material (SRM) is intended primarily for use in the value assignment of the number of Huntington's Disease (CAG) trinucleotide repeats contained in a human genomic material. The six component genomic DNA materials are from DNA extracted from cell lines derived from Huntington

Certification of Three Soil SRMs for Inorganic Environmental Measurements

Completed

The three NIST soil SRMs, 2709, 2710 and 2711, have been used worldwide by hundreds of laboratories; combined sales typically exceed 800 units per year. Use of these SRMs provides our customers with tools that are essential for achieving quality assurance in the analysis of contaminant elements in

RF Channel Propagation Measurements and Models for Communications Circuits

Ongoing

The research community has long identified the need for propagation measurements to develop and evaluate communication circuits. Since 2011, NIST has been to prototyping state-of-the-art channel sounders for measuring RF channel propagation. NIST current channel sounders include LIDAR and camera

Characterization of Additive Manufacturing Materials

Completed

Objective: Deliver new standardized feedstock and AM-built material characterization methods, exemplar data, and databases to accelerate the design and use of additive manufacturing parts in high-performance applications (e.g., critical parts in high-stress applications such as turbine blades or

Characterization of Dolphin Lung Endothelial Cells Through Quantitative Imaging

Completed

Due to their characteristics (long life span, feed at a high trophic level, extensive fat stores that can act as a deposit for anthropogenic toxin) dolphins have been proposed as a good sentinel organism in aquatic and coastal environments to monitor and understand the impact of infectious diseases

Characterization of Nano-to-Microscale Process-Induced Thermo-Mechanical Changes in Heterogeneously Integrated Microelectronics

Ongoing

Across the entire semiconductor industry, issues related to thermomechanical mismatches encountered during packaging are limiting factors in the design and fabrication of 3D modular integrated circuits. This project will develop novel and necessary metrologies for thermomechanical properties of

Characterization of 3D Photovoltaics

Completed

First Generation (thick layers of crystalline silicon) and Second Generation (thin films of CdTe, CIGS, and related materials) PV devices are both well established in the marketplace, with well defined techniques for fabrication and characterization. Third Generation PV encompasses a wide diversity

Characterizing User Equipment Emissions

Completed

Designed, demonstrated and validated a test methodology for measuring aggregate emissions over a wide range of condition. Several factors were evaluated, including the collective power distributions emitted by the UEs in a cell, the number of UEs transmitting simultaneously, the spectral properties

Charpy Machine Verification Program

Ongoing

Impact testing is required for many critical applications in the construction, machinery and equipment, defense, and energy markets. Charpy testing provides data needed to ensure the quality and reliability of structural steel products. Over 1,000 machines per year are evaluated for conformance with

Chemical/Biochemical Microsensor Science

Ongoing

Our research is focused on the basic and applied aspects of chemical sensor science and technology in the following areas: The development and evaluation of nanoscale materials, e.g., nanowires and nanotubes, for high-performance chemical sensing of gas-phase species Novel approaches for low-cost

Photograph of a unit of RM 8027 Silicon Nanoparticles (Nominal Diameter 2 nm) showing a labeled box and ampoules.

Chemical Characterization of Nanoparticles

Ongoing

NIST has a broad research program spread throughout the major operating units aimed at building the supporting technical capabilities that U.S. industry needs in their quest to develop new nanotech products with desirable new capabilities and bring them safely to market. The Chemical Sciences

Chemical Foundations for a Cannabis Breathalyzer

Ongoing

NIST's initial work in cannabis science was a series of measurements of the vapor pressure of two important cannabinoids: delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Our current effort is funded in part by interagency agreements with the ational Institute of Justice and by the NIST

Chemical Functionalization and Manipulation of Nano Materials

Ongoing

This project focuses on manipulating nanomaterials, including weakly bonded van der Waals systems, and probing emergent phenomena in these nanoengineered systems to impact technologies such as nanoelectronics, optoelectronics, quantum sensing, and quantum computing. Developing processes to

Photograph of titanium metal crystal with cubic symmetry.

Chemical Metrology for Metals, Ores, and Related Materials

Ongoing

In the arena of industrial commodities, the primary challenges are to provide measurement tools and reference materials that allow U.S. industry to establish comparability of measurement results to results obtained by customers, competitors, and regulators for the basic chemical properties of

Chemical Metrology for Polymers Manufacturing

Ongoing

This project is designed to strengthen the analytical capabilities of polymers manufacturers by introducing reference materials, critically evaluating standard test methods, and educating those industry representatives who participate in standards development organizations. Certified reference

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Advanced communications
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Forensic Science
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Health
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-Human microbiome
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Information technology
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Infrastructure
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Materials
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Metrology
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Nanotechnology
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Neutron research
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Physics
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Public safety
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Resilience
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Transportation
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