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Projects/Programs

Topic Area
Displaying 1076 - 1100 of 1667

NIST Monoclonal Antibody Reference Material 8671

Ongoing
The NISTmAb material is a recombinant humanized IgG1κ expressed in murine suspension culture. It is an »150 kDa homodimer of two identical light chains and two identical heavy chains linked through both inter- and intra-chain disulfide bonds. The protein has low abundance post-translational...

NIST/NIBIB Medical Imaging Phantom Lending Library

Ongoing
Phantoms are calibration objects that can be used to assess the accuracy, stability, and comparability of medical imaging systems. The NIST/ISMRM MRI system phantom can be used to assess scanner geometric distortion, image uniformity, signal to noise ratio (SNR), resolution, slice profile and...

NIST/NRC Fire Research Collaborations

Ongoing
Objective: To provide measurement data and analysis tools that enable accurate, efficient, probabilistic risk assessments for fire scenarios in nuclear power plants. Recent Research: Brief descriptions and links to technical reports developed from recent NIST/NRC collaborations focused on Cable...

NIST Ocean Carbon Measurements

Ongoing
NIST is committed to sustaining the quality of ocean carbon measurements by developing capabilities to provide certified reference materials for the ocean carbonate system measurements and by conducting research to understand fundamental elements of the ocean carbon thermodynamic system. NIST Ocean...

NIST OWM – NCWM: An Enduring Partnership

Ongoing
The National Conference on Weights and Measures (NCWM) was first held as the “First Annual Meeting of Sealers of Weights and Measures of the United States” in 1905 and as part of the National Bureau of Standards (NBS), which was the predecessor non-regulatory agency to the National Institute of...

NIST U.S. Pacific Islands Program

Completed
To help address environmental research and resource management in the Pacific Islands region, the 111th U.S. Congress directed NIST to "expand its capabilities and resources into the Pacific region through a Pacific Islands component of NIST" and included funding to "expand its biodiversity storage...

NIST PS1 Primary Standard for quantitative NMR (Benzoic Acid)

Completed
With explicit SI linkage, the overall impact of this apical reference material is profound—this primary standard, as well as forthcoming members of its class, provides technology transfer of chemical purity realization to the commercial sector for characterization of many thousands of organic...

NIST Rapid Microbial Testing Methods Consortium

Ongoing
The safety and quality of advanced therapies, including cell therapy, gene therapy, and tissue engineered products, must be maintained prior to patient administration. The culture-based compendial methods currently used to assess product purity (specifically to ensure absence of microbial...

NIST/SEMATECH Engineering Statistics Handbook

Ongoing
Description: The project began with a request from SEMATECH, a consortium of major U.S. semiconductor manufacturers, to update the National Bureau of Standards (NBS) Handbook 91, Experimental Statistics. Handbook 91, written by Mary Natrella of the NBS Statistical Engineering Lab, was a best-selling...

The NIST Standard Reference Photometer for Ozone Measurement Traceability

Ongoing
The concentration of ozone in the atmosphere continues to be an important global issue both scientifically and politically. Stratospheric ozone protects the Earth from harmful UV radiation, while tropospheric ozoneis a major health concern and contributes to global climate change as a greenhouse gas...

NIST Standard Reference Simulation Website

Ongoing
Molecular simulations, in particular Monte Carlo Molecular Simulation and Molecular Dynamics Simulation, are methods for computing the properties of some kind of system, for which the intermolecular interactions are specified via mathematical relationships derived from statistical mechanics. Since...

NIST Stars

Ongoing
Several current astrophysical research programs require SI traceable flux measurements (also called spectral irradiance) at accuracies higher than currently available. For example, exoplanet research requires improved host star absolute brightness knowledge to better determine habitability...

NIST and the SWGDRUG Mass Spectral Reference Library of Seized Drugs

Ongoing
Synthetic drugs such as fentanyl and its analogues are driving an unprecedented epidemic of overdose deaths in the United States. Clandestine labs create these new substances in part to evade law enforcement. This places a major burden on federal, state, and local law enforcement agencies to...

NIST Tools for Cannabis Laboratory Quality Assurance

Ongoing
Since the 1970s, cannabis (marijuana and hemp) and its constituent, Δ 9-tetrahydrocannabinol or THC, have been classified as Schedule I controlled substances. Seized evidence is tested by forensic laboratories, which verify the identity of the plant through macro- and microscopic evaluation and the...

NIST Traceable Reference Material Program for Gas Standards

Ongoing
The Gas Mixture SRM, NTRM, and EPA Protocol Programs provide a mechanism to produce needed calibration gas standards with a well-defined traceability. These mixtures are specified in the Code of Federal Regulations (CFR) to calibrate instruments to be used to monitor regulated emissions. The NTRM...

NIST Urine Albumin Standardization Program

Ongoing
Kidney disease is a major global economic and public health issue, with chronic kidney disease (CKD) representing one of the top 10 most prominent causes of death worldwide. The public health and economic impact of CKD and other kidney diseases has led to the need for the accurate detection of...

NIST Workshops on Cell-Free Expression Systems

Completed
NIST has co-hosted two cell-free workshops. NIST CELL-FREE (Comparable Engineered Living Lysates For Research Education and Entrepreneurship) Workshop (2019) The NIST CELL-FREE workshop took place in La Jolla, CA in February 2019, in collaboration with the J. Craig Venter Institute (JCVI). The...

NIST23: Updates to the NIST Tandem and Electron Ionization Spectral Libraries

Ongoing
NIST Tandem Mass Spectral Library, 2023 release 51,501compounds 60% increase over the 2020 release 399,267 precursor Ions 2.4 million spectra Fragmentation methods 49,590 HRAM (high res accurate mass) compounds 51,292 QTOF, HCD, IT-HRAM, QqQ compounds 49,561 ion trap compounds (low res., up to MS 4)...

NISTCHO

Ongoing
NISTCHO, a new mammalian cell line of interest to the biopharmaceutical and biomanufacturing communities, is now available from the National Institute of Standards and Technology. This Chinese hamster ovary (CHO) cell line has been engineered by MilliporeSigma to express a non-originator version of...

Noise Thermometry

Completed
The project has also created a quantum-based electronic temperature standard that uses the ACJVS in conjunction with measurement of the Johnson noise -- random electrical noise caused by thermal agitation in a conductor -- in resistors at arbitrary temperatures. This Johnson noise thermometry system...

Nonlinear nanophotonic control of light

Ongoing
Light-matter interactions with nonlinear materials provide a powerful tool for converting optical fields from one state to another. For example, nonlinear wavelength conversion leverages efficient scattering of photons of a single frequency to another, enabling generation of coherent sources across...

Nonlinear Optics for Quantum Information and Networking

Ongoing
Quantum networking and distributed quantum sensing will require photonic links (so called flying qubits) to connect nodes and enable scaling to larger distances and network sizes. An interconnect may consist of a photon going from one node to another where both nodes operate at the same wavelength...

Northeast Corridor Urban Test Bed for Greenhouse Gas Emissions

Ongoing
The NEC project includes multiple measurement and analysis components. The backbone of the NEC project is a network of in-situ CO2 and CH4 observation stations with continuous high-accuracy mole fraction measurements of these two greenhouse gases. In addition, the University of Maryland, Stony Brook...
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