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Projects/Programs

Keyword

Organizational Unit

Molecular Innovation in Agriculture

Ongoing

Plant science and breeding aim to develop new plant phenotypes with desired qualities, increased production, disease resistance, and traits that reduce water usage. At the federal level, plant research is conducted by the USDA's Animal and Plant Health Inspection Service (APHIS) and Agricultural

Chain orientation of polyethylene by polarization BCARS

3D Molecular Orientation Imaging

Ongoing

We have developed 3D orientation measurement techniques by analyzing polarization-dependent molecular vibrational signals based on infrared (IR) absorption [1,2] and coherent anti-Stokes Raman scattering (CARS) [3]. The two imaging modalities are complementary to each other: IR imaging broadly

Molecular Physiology

Ongoing

In close collaboration with experimentalists, we are seeking to increase the resolution, scope, and throughput of single-biomolecule and ensemble techniques, such as nanopore-based biomolecular analysis, ultrafast vibrational spectroscopy, and FRET, among others. These developments rely heavily on

Monitoring, Diagnostics and Prognostics for Manufacturing Operations

Completed

Objective - Develop and deploy measurement science to promote the implementation, verification, and validation of advanced monitoring, diagnostic, and prognostic technologies to minimize unplanned downtime and optimize planned downtime in manufacturing operations. What is the technical idea

Monoclonal Antibody Mass Spectral Libraries

Ongoing

Intended Impact Modern mass spectrometers used in the field of proteomics and glycomics are capable of profiling hundreds, and even thousands of molecules in a single experiment. Each of these compounds is isolated and fragmented to form a mass spectrum. Therefore, interpretation of these mass

Mouse Allelic Ladder

Ongoing

What is an allelic ladder? An allelic ladder is a mixture of highly characterized alleles (known size and sequence) that are generated using the same primers as the test samples and are used during capillary electrophoresis for accurate allele call determination. Why is an allelic ladder important

Mpox (MPXV) Synthetic DNA PCR Standards

Ongoing

A new material from NIST can aid in the evaluation and development of selected qPCR assays for the mpox virus. We are offering a unit free of charge in exchange for your feedback, which will help us improve and further develop the material. Questions? Contact MPXV-RGTM [at] nist.gov (MPXV-RGTM[at]nist[dot]gov) . NIST supports the

Multidimensional Chromatography

Ongoing

The development of robust analytical methods remains one of the most important (and costly) parts of chemical metrology. The separation of targeted constituents from other components in a sample matrix is necessary for accurate and precise measurements. Multidimensional chromatography is an

Multi-Domain Knowledge Planes for Service Federation for 5G & Beyond Public Working Group (MDKP-PWG)

Ongoing

A. Problem Statement In the 5G and Beyond Era there are interesting growing trends on Requirements for Enablers for Cross-Industry Sectors End-to-End (E2E) Services Innovation and Delivery Agility and how to leverage dynamic resource and assets availability wherever and whenever so they can be

Multifunctional 3D Printable Polymer-Metal Composites

Ongoing

Recent advances in additive manufacturing (AM) have positioned metals and polymers as two key materials. Typically, AM of these two materials involves incompatible methods and conditions. The novel multifunctional polymer-metal composites in this project incorporate low-melting alloys with

Multimodal Biometrics

Ongoing

MBARK: to advance standards in biometric acquisition client technologies MBGC: to focus R&D community on multiple biometric applications to advance innovation while NIST assesses performance of emerging technologies

Multi-modal AI Models with Application to Precision Medicine

Ongoing

The main goals of this project are listed as follows. Define ML/DL architectures targeted at diverse datasets consisting of spectral images and metadata of different types. Train and test the resulting ML/DL networks on data from the MP and select the best ones. Using the above-developed ML/DL

Multi-Organ Microphysiological Systems

Ongoing

We are developing tissue chips and multi-tissue microphysiological devices that support the culture of multiple tissues with physiologically relevant connections and streams of cell-culture medium. The goal in this project is to construct a device that realistically mimics human metabolism as a

Multiparametric Analysis of Network Growth Process via Combined Experimental and Computational Approaches

Ongoing

We have developed techniques that use simultaneous measurements of evolution of multiple polymerization properties combined with computational approaches. In-situ measurements including stress evolution, chemical evolution, and temperature changes during polymerization and computation approaches can

Multiparametric Measurement and Analysis of Cell Behavior on Extracellular Matrices

Completed

The rational design of biomaterials which can elicit desired cellular responses is an important requirement for tissue engineering. Understanding the role of different cues that extracellular matrices provide cells is an important component of achieving this objective. Type 1 collagen is a

Multiple Biometric Evaluation (MBE)

Completed

MBE 2D Still Update The evaluation of 2D face recognition algorithms yielded two reports. First, NIST Interagency Report 7709 gave results for both verification and identification algorithms. Second, the NIST Interagency Report 7830 surveyed compression and resolution parameters for storing face

Multiple Biometric Grand Challenge (MBGC)

Completed

Background Over the last decade, numerous government and industry organizations have or are moving toward deploying automated biometric technologies to provide increased security for their systems and facilities. Six U.S. Government organizations recently sponsored the

Multiplexed "Detectorless" Electrophoresis

Completed

Intended impact: In the biological sciences, there is an increasing need for measurement tools that can provide high-throughput, high-quality data (consider drug discovery and systems biology, for example). Capillary electrophoresis (CE) is fast, requires only small amounts of sample and reagents

Multiscale MD-FEM Methodology

Completed

MSED, as a part of the MGI effort within NIST, is developing a multiscale modeling schema, statically coupling finite element modeling (FEM) to atomistic Molecular Dynamics (MD) 1. This methodology allows a far more realistic representation of physical phenomena than that obtained by applying each

Multiscale Modeling and Validation of Semiconductor Materials and Devices

Ongoing

The limitations of scaling traditional CMOS (complementary metal-oxide semiconductors) designs have necessitated that the semiconductor industry consider new materials and design concepts. For wide bandgap semiconductor devices, optimization of materials and fabrication processes is needed to

Multiscale structure and dynamics in advanced technological materials

Ongoing

New technologies increasingly harness materials phenomena that operate across many length-scales: e.g., in selective gas adsorption, additive manufacturing, new alloy designs, or advanced concretes. To overcome technology barriers, it is no longer sufficient just to characterize the materials

Nail to Nail (N2N) Fingerprint Capture Challenge

Completed

Updates 12 December 2019: Data from the Challenge has been released as Special Database 302. Future updates with N2N data will appear on the Special Database 302 page. 16 September 2019: We have begun work with Certified Latent Print Examiners to annotate our dataset with EFS Profile 2 information

Nano-biophotonics for molecular imaging

Ongoing

Nano-biophotonics consists of four broad areas: molecular bioimaging; nano-biosensors; multiplexed bioassays ; and nanotechnology-based medical practices for diagnosis and therapy. Success in these areas is challenged by the underlying complexity of biological systems. Major levels of complexity and

Nanocalorimetry

Ongoing

The global market for semiconductor chips is $270 billion. Growth in this industry is driven by the need to enhance performance by packing more transistors into the same chip area, with a relationship between feature size and time that approximately follows Moore's Law. As the feature size shrinks

Nanocalorimetry Measurements

Ongoing

Accurate thermodynamic measurements are essential to understand fundamental properties of materials, providing direct and quantifiable insight into the thermodynamics of thin film reactions and phase transitions. Going forward, new classes of materials may only be synthesized as thin films, a scale

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Advanced communications
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Environment
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Fire
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Forensic Science
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-Firearms and toolmarks
-Forensic biometrics
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-Trace evidence
Health
-Biopharmaceuticals
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-Food and nutrition
-Human microbiome
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Information technology
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-Location based services
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-Networking
--Mobile and wireless networking
--Network management and monitoring
--Network modeling and analysis
--Network security and robustness
--Network test and measurement
--Next generation networks
--Protocol design and standardization
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Infrastructure
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-Process improvement
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-Product data
-Robotics in manufacturing
--Agility and adaptability
--Collaborative robots
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Materials
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--Mechanical properties
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-Metals
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Mathematics and statistics
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-Modeling and simulation research
-Numerical methods and software
-Statistical analysis
-Uncertainty quantification
Metrology
-Amount of substance
-Dimensional metrology
-Electrical / electromagnetic metrology
-Flow metrology and rheology
-Force metrology
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Nanotechnology
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