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Projects/Programs

Keyword

Organizational Unit

Quantifying the environmental contributions to mass change

Ongoing

Experiments using two types of centimeter scale oscillators are described: the double paddle oscillator (DPO) and a commercial quartz crystal microbalance (QCM). Double Paddle Oscillator (DPO) Since mass changes are mostly on the surface of mass artifacts, we have implemented a micro-weighing sensor

Quantifying Uncertainty in Accelerometer Sensitivity Studies

Ongoing

DESCRIPTION: International Key Comparisons are performed. The key comparison reference value for charge sensitivity as a function of frequency and the accompanying uncertainty are the principal objectives of these studies. In a suggested mixed effects model several methods for evaluation of this

Quantitative Assessment of Defects and Related Modeling Parameters in GaN Semiconductor Devices

Ongoing

Key performance metrics like breakdown voltage, switching speed, gain stability, and maximum operating frequency are limited by material defects in AlGaN/GaN devices. Defects also play a role in device degradation over time. Although these materials have been studied for over twenty years with a

Quantitative, Cell-based Immunofluorescence Assays

Ongoing

Analysis of signaling events within individual cells with microscopy imaging has several advantages over non-imaging techniques. The principal advantage of imaging cytometry over plate reader assays and even other single cell techniques such as flow cytometry is the potential for collection of

Quantitative Flow Cytometry Measurements

Ongoing

Flow cytometry is an essential tool for basic biotechnological and immunological research, the clinical discovery of potential therapeutics, development, and approval of drugs and devices, disease diagnosis, and therapeutic treatment and monitoring. For example, flow cytometry is commonly used in

Quantitative Information from Images

Ongoing

Projects: Quantifying Amount of Material through Light Measurement Fluorescence and Luminescence Imaging for Surgical Guidance Fluorescence-guided imaging devices are being used for navigation in minimally invasive surgical procedures to increase a patient’s positive clinical outcomes and shorten

Quantitative MRI

Ongoing

Future directions may focus on multimodal imaging, techniques that use MRI as either a base or as a complimentary technique. Multimodal imaging combines information from two or more imaging modalities such as MRI, computed tomography (CT), positron emission tomography (PET), and ultrasound (US)

Schematic of unresolved imaging of a periodic structure. Extracting deep-subwavelength information from such images requires mastery of several techniques; this project seeks to integrate machine learning for metrology.

Quantitative Nanoscale Imaging Through Artificial Intelligence

Ongoing

This project extends optical capabilities for the characterization of nanoscale devices as they increase in complexity, with challenging new materials properties, thicknesses, and length scales that challenge simplistic applications of the fundamental equations of electromagnetism. Critical

Quantitative, Traceable Determination of Cell Viability Using Absorbance Microscopy

Ongoing

The current gold standard for cell viability measurements is the trypan blue assay. Trypan blue dye enters dead cells that have a ruptured membrane. As a result, the dead cells are stained blue. Live cells with an intact membrane, on the other hand, do not absorb the dye molecules and remain

Quantum Bioimaging

Ongoing

Our efforts in BBD are focused on using the quantum nature of light to facilitate enhanced and novel measurement technologies for biological samples. For example, so-called bright squeezed laser sources enable imaging and sensing with less noise than is classically possible. Additionally, entangled

Quantum Biophotonics

Ongoing

Applying recent advances in single-photon detection along with novel data processing methods developed in the quantum optics community opens fundamentally new opportunities for faint-light metrology down to that related to just a single molecule – i.e. precisely the conditions for bio-optical

Quantum Characterization

Ongoing

The BCQT serves as a resource to academic and industry quantum research groups for measurement of superconducting microwave resonators in a well-characterized cryogenic environment using traceable, open-source methods developed in broad consultation with companies, universities, and NIST. This

Quantum Communications and Networks

Ongoing

Key Components of Quantum Repeaters and Quantum Network Systems Single Photon Sources: An ideal single photon entangled pair source for a quantum repeater application should satisfy several conditions simultaneously. Since photons must interact efficiently with a quantum memory, the source must emit

Quantum Computation and Simulation with Neutral Atoms

Ongoing

Advances in quantum information have the potential to significantly improve sensor technology, complete computational tasks unattainable by classical means, provide understanding of complex many-body systems, and yield new insight regarding the nature of quantum physics. At NIST and around the world

This image shows a planar rf ion trap designed for experiments with magnetically-driven quantum gates.

Quantum Computing with Trapped Ions

Ongoing

Quantum Computing with Trapped Ions We pursue proof-of-concept experiments in quantum information processing and quantum control with trapped ions. In addition to pushing current limits on traditional quantum gate-based architectures for quantum computing we explore alternative approaches to

Quantum Conductance

Ongoing

Inset: Example of an array device design. (a) An illustration of the graphene quantized Hall array resistance device with NbTiN interconnections (dark grey) between individual QHR elements (light grey) and the positions of the bonding wires that were used for the measurement (blue). The red inset

Quantum Many-Body Physics, Quantum Optics, and Quantum Information

Ongoing

Differences between typical AMO and condensed matter systems bring with them exciting new physics. In contrast to condensed matter systems, AMO systems are often studied far out of equilibrium, are evolving in time, and are subject to dissipation. As a result, many-body AMO systems open a whole new

Quantum matter from atomic gases

Ongoing

Ultracold atoms are a very different sort of system than conventional materials, composed of a few hundred to a few hundred million atoms, with densities ranging from 10 12 cm -3 to 10 15 cm -3, and at temperatures from below 1 nK to a couple uK. These atomic systems are unique in the simplicity of

ion trap with integrated fiber Fabry-Perot cavity

Quantum Networking with Trapped Ions

Ongoing

The goal of a quantum network is to establish entanglement as a resource between distant locations. Shared entanglement over long distances may enable distributed quantum computing, quantum-enhanced long-baseline interferometry, the transmission of complex quantum states, or a variety of other

Quantum Nonlinear Optics for Metrology and Networking

Ongoing

We have generated "twin beams" of light using four-wave mixing (4WM) that are correlated at a level better than can be displayed by classical radiators. One particularly useful feature of the 4WM technique is that the light can easily be made in multiple spatial modes. That is, images with quantum

Quantum Optical Networks

Ongoing

The program's technical research areas are: Architecture research for Quantum Optical Networks and integration with classical networks Management (label, identify, track) and Control Plane (signal and route optical paths) Software Stacks Performance monitoring for end-to-end Quality of Entanglement

Quantum Pascal: Fixed Length Optical Cavity (FLOC) Pressure Standards

Ongoing

This project enables a quantum-based, SI-traceable method for realizing the pascal (Pa) while improving accuracy and allowing the replacement of existing mercury manometer pressure standards. The Fixed Length Optical Cavity (FLOC) pressure standard is a laser-based, SI-traceable primary pressure

Quantum Physics Theory

Ongoing

The scope of the work ranges from calculations of QED effects in atoms to detailed studies of photon wave functions.

Quantum Radiometry

Ongoing

For quantum applications, it is important to generate quantum states of light and detect them with extremely high efficiency. This project explores the metrology challenges associated with precision measurement of single photon sources and detectors. The classical photonic radiometry techniques used

Quantum Simulation and Sensing with Trapped Ions

Ongoing

Entanglement between individual quantum objects exponentially increases the complexity of quantum many-body systems, so systems with more than 30-40 quantum bits cannot be fully studied using conventional techniques and computers. To make progress at this frontier of physics, we are pursuing Feynman

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Advanced communications
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Bioscience
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Health
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