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Standards

Projects/Programs

Keyword

Organizational Unit

Fatty Acids in Human Serum and Plasma Quality Assurance Program (FAQAP)

Completed

Interlaboratory comparison studies of the FAQAP focused on the measurement of 24 fatty acids in selected serum and plasma matrices. Frozen or freeze-dried serum or plasma samples were sent to laboratories for analysis together with control materials. Results were returned to NIST for data evaluation

Food Nutrition and Safety Measurements Quality Assurance Program (FNSQAP)

Ongoing

As part of a revamp of QAPs in 2021, NIST established the FNSQAP to support the NIST Food Safety Program and Measurements and Standards to Support Nutrition Labeling. Participants measure nutrient components (e.g., minerals, vitamins, fatty acids, dietary fiber) and contaminants (e.g., toxic

The inside of a DNA extraction robot hold tube in a rack

Forensic Genetics

Ongoing

Since the late 1980s, NIST has had scientists involved in DNA testing (aka "DNA Fingerprinting"). Early concerns over measurement accuracy and poor quality control of forensic DNA tests caused the Department of Justice to call upon NIST scientists to help with standards development and technology

Fossil Fuel Standard Reference Materials

Ongoing

The regulatory requirements with respect to air quality and fossil fuel specifications are continually changing, and consequently the associated measurement needs of the fossil fuel energy industries also change. For example, in recent years there has been a dramatic reduction in the allowable

Frequency Measurement and Analysis Service (FMAS)

Ongoing

Subscribers to the NIST service receive a complete frequency measurement system which includes everything needed to make precision frequency measurements that are traceable to NIST. An easy-to-read instruction manual makes installation a snap. Once the system is installed, it's easy to get started

Functional Barriers for Low-Flammability Products

Ongoing

This project enables low-flammability products without flame retardants by providing methods to assess functional barriers, advancing their performance, and exploring their use in multi-layer products for critical applications.

Fundamental Guided Wave Metrology

Ongoing

The science of microwave measurements is expanding in many different directions. There is a constant push to use higher frequencies. Signals are becoming much more complex and include modulation effects, multiport/differential signals, complex waveforms, and other unusual signal schemes. On-wafer

Gas properties for flow metering

Ongoing

NIST has two on-line databases that include accurate gas viscosity values: SEMIPROP - NIST Standard Reference Database 134 - for selected semiconductor process gases NIST Chemistry WebBook - for heat transfer fluids, components of air, components of natural gas [Note: as of February 2014, the NIST

Gene Delivery Systems

Ongoing

Viral Vectors Viral vectors are a critical tool for delivering DNA or RNA into patient’s cells. Common viral vectors for gene therapy include adenovirus, lentivirus, and adeno associated virus. Administration of viral vectors can occur in vivo or ex vivo , such as for adeno associated virus or

Genome in a Bottle Workshops

Ongoing

GIAB has held 1-2 workshops each year since being formed in 2012. These workshops include progress updates, presentations about related work, and planning for new samples and analyses. Following are links to agendas, reports, and presentations from past workshops. Workshop Reports APRIL 2020

Picture for Hardness and Coating Thickness Standardization and Measurements Project Including Equipment and Standards Organizations

Hardness Standardization and Measurements

Ongoing

DESCRIPTION Purpose: Provide measurement traceability for the Knoop, Rockwell, and Vickers hardness scales and for coating thickness measurements that are based on magnetic methods. Goals: Harmonization of hardness and coating thickness testing protocols, in pursuit of reduction of measurement

Health Assessment Measurements Quality Assurance Program (HAMQAP)

Completed

Participants in the HAMQAP measured concentrations of nutritional and toxic elements, fat- and water-soluble vitamins, fatty acids, active and/or marker compounds, and contaminants in samples distributed by NIST.   Samples that represent human intake (e.g., foods, dietary supplements, tobacco) were

High-Precision Isotopic Reference Materials

Ongoing

A new generation of multi-collector IRMS, utilizing both inductively coupled plasma and thermal ionization sample sources, is now capable of measuring isotope ratios with extremely high precision – a few parts in 10 6. This new measurement capability has caused a minor revolution in the use of

Human Gut Microbiome Reference Material

Ongoing

The most common measurements currently being used to describe these complex microbial communities are: NGS-based metagenomics Mass spectrometry-based metabolomics In either case, no fit-for-purpose standards exist that enable researchers to compare results generated across different laboratories and

Identification, Suitability Testing, and Property Determination from Untargeted Measurements

Ongoing

In many applications, detailed knowledge of a fluid mixture’s physical behavior is needed. This can include physical properties such as viscosity and qualitative properties such as solubility. For instance, a dissolved polymer may suddenly precipitate out of solution when exposed to saline, and if

IDMS Standards Activities

Ongoing

This work focuses on U.S. participation on related IDM standards activities, development of standards and metrics, and related outreach. The work program for this project includes: 1. U.S. representation on the following ISO/IEC JTC 1 subcommittees: a. ISO/IEC JTC 1 SC17 b. ISO/IEC JTC 1 SC 27 c

Actionable Intelligence and Industrial AI

Industrial Artificial Intelligence Management and Metrology (IAIMM)

Ongoing

IAIMM has identified IAI systems for decision making, planning, and control in manufacturing as a prime candidate for better Standard Operating Procedures (SOPs) centered on both use and evaluation. The specific use case of multi-stage manufacturing presents a broad scope of application to

Industrial Wireless Systems

Ongoing

The Industrial Wireless Systems project addresses the unique challenges of deploying wireless technologies in industrial environments, where performance is non-negotiable. From factories to power plants, our research ensures wireless solutions deliver the precision and robustness required for real

Inkjet Printing and Precision Deposition

Ongoing

Inkjet Droplet Metrology: Drop-on-Demand (DOD) inkjet printing allows precise deposition of picoliter (pL)-size droplets of solutions containing organic or inorganic materials. These drops can be used to create unique patterns, structures, and coatings and build 3-D microstructures making it a

Inorganic Phase Equilibrium Data

Ongoing

Every deliberate effort to develop a new material or to improve processing begins with chemical composition and the conditions (temperature, pressure) under which pure compounds and their mixtures are stable ( an equilibrium phase diagram ). In the absence of such information, materials scientists

Photograph of a weathered metal surface labeled Danger Toxic Fumes

Instrument Standards for Detection of Hazardous Chemical Vapors

Ongoing

Chemical threat detection is a challenging problem. Contaminants must be accurately identified and quantified often in complex mixtures where non-toxic components can often obscure the measurement. Furthermore, highly toxic chemicals are problematic at low concentrations, requiring ultra-sensitive

Interdisciplinary Projects

Ongoing

Current: DARPA CCU (Computational Cultural Understanding) Past: IARPA MATERIAL (Machine Translation for English Retrieval of Information in Any Language) DARPA LORELEI (Low Resource Languages for Emergent Incidents) and LoReHLT (Low Resource Human Language Technologies) DARPA BOLT (Broad

Photograph showing Gas Pump Octane Options

International Collaborations to Improve the Accuracy of Gas Primary Standards

Ongoing

The goal is to use the results from intercomparisons to assist in determining and correcting any large differences between gas standards from different NMIs. When results are within the stated uncertainty bounds, then the NMIs gas standards are considered to be equivalent. This enables the use of

A chart showing the various sectors served by the Laser Power & Energy Meter calibrations project as of 2025

Laser Power and Energy Meter Calibrations

Ongoing

We serve Industry, DoD, and research institutions by calibrating instruments used to measure the power or energy emitted by a laser, or single photon source. From Single Photons to Kilowatts, Longwave Infrared to Deep Ultraviolet, Free-space and Fiber, we can calibrate your instruments. The chart to

Live Cell Imaging of Induced Pluripotent Stem Cell Populations

Ongoing

As part of our program in Cell Biology , our live cell image program supports the advancement of induced pluripotent stem cell (iPSC) technology in three ways: 1) Identification of process control measurements: A critical component to the translation of iPSCs into therapeutic applications is to

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