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Projects/Programs

Displaying 51 - 75 of 203

Development of Serum-Based SRMs to Assess Nutritional Status

Ongoing
Vitamin deficiencies are generally considered rare in the U.S., but a growing body of evidence suggests that certain deficiencies may be more prevalent than originally thought. For example, it has been estimated that 10 % to 15 % of adults over the age of sixty are affected by vitamin B 12

Development of SRM 2669 for Accurate Assessment of Arsenic Exposure

Ongoing
Arsenic exposure in the U.S. population is an important part of the NHANES program conducted by CDC because dietary exposure to arsenic can cause serious health effects. A major challenge in the arsenic exposure assessment is that arsenic exists as various species in nature, and the toxicity of

Development of SRM 955c Toxic Elements in Caprine Blood

Completed
Intended Impact Over the last three decades, NIST, with support from the Centers for Disease Control (CDC), and in conjunction with the New York State Department of Health’s (NYSDOH) Wadsworth Center, has produced a number of frozen whole blood certified reference materials containing endogenous

Dietary Supplement Laboratory Quality Assurance Program (DSQAP) Consortium

Ongoing
The objective of the DSQAP Consortium is to develop and evaluate measurement methods and standards to support quality and safety for the dietary supplement testing community. Approximately 75% of the U.S. population takes dietary supplements, including vitamins and mineral supplements, representing

Dietary Supplement Laboratory Quality Assurance Program (DSQAP)

Ongoing
Approximately 75% of the U.S. population takes dietary supplements, including vitamins and mineral supplements, representing an annual expenditure of more than $20 billion. Regulations, driven by reported cases of inaccurate labeling, adulteration, contamination (with pesticides, heavy metals, or

Digital PCR

Ongoing
With appropriately validated assays, digital polymerase chain reaction (dPCR) determines the number of DNA targets (copies) per reaction partition, without the need for a standard curve. Reaction partitions can be in the form of fixed chambers in a microfluidic device, referred to as chamber digital

Digital Thread for Manufacturing

Ongoing
Purpose and Goals This project will provide research advances in product-definition standardization, conformance testing, and cybersecurity of data assets. Digital thread standards capabilities and infrastructure - Smart connected manufacturing requires the effective communication of the product

Digital Video Exchange Standards

Ongoing
NIST is working to develop a data export standard in conjunction with the stakeholder community. The goal of standardization is to increase evidentiary value and timeliness of CCTV video data; and to facilitate interoperable data sharing between CCTV/DVR owners and Law Enforcement; as well as among

DNA Mixture Interpretation

Ongoing
Interlaboratory Studies Mixture interlaboratory studies provide a means to assess a laboratory's ability to process and interpret DNA mixtures. Initial ‘Mixed Stain’ studies (published in 2001) provided physical samples for DNA profiling with the first commercial STR typing tests. Later, mixture

Documentary Standards: IEC 62755 Standard N42 Data Format

Ongoing
The IEC 62755 standard specifies the XML data format that shall be used for both required and optional data to be made available by radiation measurement instruments. The performance requirements for these types of instruments are described in other IEC standards. The output from these instruments

Dynamic Plasticity: Non-Equilibrium Mechanics

Ongoing
The optimization of high-speed machining processes through powerful finite element modeling techniques is an important pathway to American manufacturing competitiveness in an increasingly competitive global marketplace. Quantitatively accurate simulations of machining rely on robust constitutive

Electric Power Metrology and the Smart Grid

Ongoing
Major advancements in electric power generation, transmission, distribution and loads over the last 20 years have led to improvements, reliability, robustness, efficiency and energy security unlike anything from the proceeding 80 years. Combined, this power grid modernization has been called the

Electromagnetic Field Strength Metrology

Ongoing
NIST calibrates electrically-small field probes from 10 megahertz – 40 gigahertz. These measurements are done in facilities that are periodically compared against other National Metrology Institutes in conjunction with the Bureau International des Poids et Mesures (BIPM). This assures international

Electronic Material Characterization

Ongoing
Manufacturing optimized devices that incorporate newly-emerging materials requires predictable performance throughout device lifetimes. Unexpected degradation in device performance, sometimes leading to failure, is often traceable to poor material reliability. Reliability is rooted in the stability

Engineering Biology Metrics and Technical Standards for the Global Bioeconomy

Ongoing
Stakeholders from the Americas, Asia and Australia, and Europe and Africa, came together through a series of regional workshops in Washington D.C., Singapore, and Brussels, respectively, to identify specific areas for development, both technical and non-technical towards continued scale-up and economic growth across the bioeconomy.

Farad and Impedance Metrology

Ongoing
The primary facility for connecting the U.S. legal system of electrical units to the international system of units is the NIST calculable capacitor, with which the measurement of capacitance is effectively achieved through a measurement of length. Both the calculable capacitor and the chain of high