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Metrology

Projects/Programs

Keyword

Organizational Unit

OWM Training Program: Metrology, Metrication, and More!

Ongoing

OWM offers a variety of in-person, online, and "blended" training classes and materials that provide guidance instruction on national legal metrology standards, weights and measures field inspection procedures, and laws and regulations related to packaging and labeling. OWM provides technical

Peptide Mass Spectral Libraries

Ongoing

Intended Impact Modern mass spectrometers used in the field of proteomics are capable of profiling thousands of peptides in a single experiment. Each of these peptides is fragmented to form a mass spectrum. Therefore, interpretation of these mass spectra is a critical step in the experimental

TOP: Image of fluorescent reference material on microscope. BOTTOM: Charting of microscope control parameters.

Performance Benchmarking and Intensity Calibration of a Widefield Fluorescence Microscope

Ongoing

Widefield fluorescence microscopy is a highly used tool for visually assessing biological samples and for quantifying cell responses. Despite its widespread use in high content analysis and other imaging applications, few published methods exist for evaluating and benchmarking the analytical

Personal Body Armor

Completed

To quantify the impact of mechanical degradation on ballistic fibers, NIST developed a novel device for controlled folding of yarns and woven fabrics. In addition, we developed test protocols that employ single fibers to assess the effect of folding using a recently developed modified single fiber

Phase and Amplitude Noise Calibration Services

Ongoing

The primary responsibility of the Phase Noise Metrology Group is to develop and provide calibration services for industrial, military, and commercial organizations to support the core mission of NIST. The PM and AM noise measurements require traceability and certification of devices such as phase

Measurement device for signals in the W band (75-110 GHz)

Phase and Amplitude Noise Metrology

Ongoing

The group provides high-precision measurement of electromagnetic signals in the radio-frequency, microwave and optical range. These measurements include phase noise, amplitude noise and perturbations due to vibration and temperature. Such precision measurements support high-value applications such

Schematic of quantum entangled molecules or nanoparticles in dual cavity system.

Photonic Quantum State Imaging Metrology

Ongoing

Fundamental understanding of quantum behavior of single molecules, which is a favorable candidate for quantum information processing technologies, has advanced gradually, relying on empirical studies mostly. This requires a measurement platform to study fundamental quantum characteristics in single

Physics and Hardware for Intelligence

Ongoing

Our work in this area can be separated into two categories: conceptual and experimental. Please read our publications linked below for more information. Experimental: Our latest generation of synaptic circuits are described in a 2024 paper published in APL Machine Learning. These circuits are our

Polymer Formulations

Completed

Bringing new and optimized formulated products to market requires measurements that will allow rapid assessment of the structure and properties of multicomponent mixtures over large parameter spaces. To this end, we are developing microfluidic "lab on a chip" technologies that enable researchers to

Picture of PBD set up for wavelength measurement

Powder Diffraction SRMs

Ongoing

This program strives to produce the highest-quality, traceable powders and other artifacts for x-ray diffraction calibration. (to be completed)

Precision Electro-Mechanical Experiments (PREME)

Ongoing

NIST-4 Kibble Balance Previously called ‘the Electronic Kilogram’ Project, a major component of PREME is the realization of SI unit of mass, the kilogram, using the NIST-4 Kibble balance, the fourth generation of Kibble balances at NIST. This is accomplished through a high-accuracy comparison of

Precision Measurement Grants Program

Ongoing

If funding is available, one new grant in the amount of $50,000 per year will be awarded for the initial period of October 1 through September 30 of the following year. The award may be continued for up to two additional years; however, future or continued funding will be at the discretion of NIST

Precision Timing for Smart Grid Systems

Completed

Objective: The key objective is to support the power sector industry through research and development in the metrology for online and predictive precision timing characterization necessary for grid monitoring and control applications. This project strives to support to the Smart Grid Testbed and the

Precision X-ray Emission Line Measurements

Ongoing

Precise knowledge of the shape and position of x-ray emission lines is the basis of connecting x-ray diffraction measurements to the Système Internationale d'Unités (SI), the official worldwide standard for making any measurement. Measurements of position of x-ray emission lines have been made been

Protein rheology measurements

Ongoing

Intended Impact Why does the health-care industry care about rheology and scattering of protein solutions? Operations. Viscosity is a critical and fundamental constitutive input for drug delivery, device design and manufacturing. For example, high viscosity leads to poor syringeability due to high

Qualification for AM Feedstocks, Machines and Processes

Completed

Objective - To develop, utilize, and analyze test methods and protocols for characterizing the feedstocks, machines, and processes in metal-based additive manufacturing to enable optimum usage and to reduce the cost and time needed for qualification. What is the Technical Idea? Qualification of AM

Quantifying the environmental contributions to mass change

Ongoing

Experiments using two types of centimeter scale oscillators are described: the double paddle oscillator (DPO) and a commercial quartz crystal microbalance (QCM). Double Paddle Oscillator (DPO) Since mass changes are mostly on the surface of mass artifacts, we have implemented a micro-weighing sensor

Quantifying Uncertainty in Accelerometer Sensitivity Studies

Ongoing

DESCRIPTION: International Key Comparisons are performed. The key comparison reference value for charge sensitivity as a function of frequency and the accompanying uncertainty are the principal objectives of these studies. In a suggested mixed effects model several methods for evaluation of this

Quantitative Assessment of Defects and Related Modeling Parameters in GaN Semiconductor Devices

Ongoing

Key performance metrics like breakdown voltage, switching speed, gain stability, and maximum operating frequency are limited by material defects in AlGaN/GaN devices. Defects also play a role in device degradation over time. Although these materials have been studied for over twenty years with a

Quantitative Flow Cytometry Measurements

Ongoing

Flow cytometry is an essential tool for: basic biotechnological and immunological research, the clinical discovery of potential therapeutics, development and approval of drugs and devices, disease diagnosis, and therapeutic treatment and monitoring For example, flow cytometry is commonly used in pre

Quantitative, Traceable Determination of Cell Viability Using Absorbance Microscopy

Ongoing

The current gold standard for cell viability measurements is the trypan blue assay. Trypan blue dye enters dead cells that have a ruptured membrane. As a result, the dead cells are stained blue. Live cells with an intact membrane, on the other hand, do not absorb the dye molecules and remain

Quantum Conductance

Ongoing

The quantum Hall effect (QHE), and devices that exhibit it, will continue to serve as the foundation of the ohm while also expanding its territory into other SI derived units. The world adopted the quantum SI in 2019, and it remains essential that the global metrology community pushes forth and

Quantum Pascal: Fixed Length Optical Cavity (FLOC) Pressure Standards

Ongoing

This project enables a quantum-based, SI-traceable method for realizing the pascal (Pa) while improving accuracy and allowing the replacement of existing mercury manometer pressure standards. The Fixed Length Optical Cavity (FLOC) pressure standard is a laser-based, SI-traceable primary pressure

Quantum Physics Theory

Ongoing

The scope of the work ranges from calculations of QED effects in atoms to detailed studies of photon wave functions.

Quantum Radiometry

Ongoing

For quantum applications, it is important to generate quantum states of light and detect them with extremely high efficiency. This project explores the metrology challenges associated with precision measurement of single photon sources and detectors. The classical photonic radiometry techniques used

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