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Metrology

Projects/Programs

Keyword

Organizational Unit

New Gas Standard Reference Materials to Support the Automotive Industry

Completed

NIST currently supports AIGER members by maintaining reasonable inventories of required gas SRMs that consist of dilute mixtures of key pollutants such as carbon dioxide, carbon monoxide, hydrocarbons, and nitric oxide. Newer vehicles produce lower levels of these pollutants because their engines

NIST Automated Vehicles Program

Ongoing

Measurement science and standards are needed to support the safe and predictable operation of future automated vehicles (AVs), which have great potential to significantly impact our daily lives and improve the competitiveness of our economy. A FY22 NIST Strategic and Emerging Research Initiatives

NIST and Autonomous Vehicles

Ongoing

Why Autonomous Vehicles? Autonomous vehicles are projected to influence key aspects of everyday life including transportation, goods delivery, manufacturing, public safety, and security. In addition, the autonomous vehicle sector is a vastly inter-disciplinary field with subject areas including

The NIST Chemistry Webbook

Ongoing

Intended Impact It is part of NIST's mission to distribute Standard Reference Data to scientists, engineers, educators, and the general public. The NIST Chemistry WebBook is intended to help fulfill NIST's mission by distributing such data over the Internet. Objective Develop a web site

NIST Combinatorial Methods Center (NCMC)

Completed

Established in 2002, the NCMC combines pioneering research and customer engagement to foster wide-spread adaptation of combinatorial and high-throughput methodologies. NCMC research addresses key challenges faced by polymer researchers who want to employ combi. In particular, the NCMC creates new

NIST Flow Cytometry Standards Consortium 

Ongoing

Advances in cell and gene-based therapeutics as well as other regenerative medicine products have increased the need for high quality, robust, and validated measurements for cell characterization. Flow cytometry, including imaging cytometry, has emerged as an important platform due to its ability to

NIST Living Measurement Systems Foundry

Ongoing

To enable the production of high-throughput, high-quality data that meets the rapidly evolving needs of current and future stakeholders, NIST has established an automation facility for the growth, manipulation, sample preparation, and measurement of engineered microbes. The core of the facility

NISTmAb RM8671 vial and 3D printed model

NIST Monoclonal Antibody Reference Material 8671

Ongoing

The NISTmAb material is a recombinant humanized IgG1κ expressed in murine suspension culture. It is an »150 kDa homodimer of two identical light chains and two identical heavy chains linked through both inter- and intra-chain disulfide bonds. The protein has low abundance post-translational

group photo taken at NCWM 2023 Annual Meeting; Craig VanBuren, Don Onwiler, and Mahesh Albuquerque of NCWM, Laurie Locascio and Katrice Lippa of NIST, Gene Robertson of NCWM, David Sefcik

NIST OWM – NCWM: An Enduring Partnership

Ongoing

The National Conference on Weights and Measures (NCWM) was first held as the “First Annual Meeting of Sealers of Weights and Measures of the United States” in 1905 and as part of the National Bureau of Standards (NBS), which was the predecessor non-regulatory agency to the National Institute of

NIST PS1 Primary Standard for quantitative NMR (Benzoic Acid)

Completed

With explicit SI linkage, the overall impact of this apical reference material is profound—this primary standard, as well as forthcoming members of its class, provides technology transfer of chemical purity realization to the commercial sector for characterization of many thousands of organic

Photograph of the NIST Standard Reference Photometer showing the component modules consisting of optical bench with sample and reference tubes, ozone generator module with controls and tubing, and control module with numeric LED displays.

The NIST Standard Reference Photometer for Ozone Measurement Traceability

Ongoing

The concentration of ozone in the atmosphere continues to be an important global issue both scientifically and politically. Stratospheric ozone protects the Earth from harmful UV radiation, while tropospheric ozoneis a major health concern and contributes to global climate change as a greenhouse gas

Evolution of Flat-histogram Monte Carlo Simulation

NIST Standard Reference Simulation Website

Ongoing

Molecular simulations, in particular Monte Carlo Molecular Simulation and Molecular Dynamics Simulation, are methods for computing the properties of some kind of system, for which the intermolecular interactions are specified via mathematical relationships derived from statistical mechanics. Since

NIST Tools for Cannabis Laboratory Quality Assurance

Ongoing

Since the 1970s, cannabis (marijuana and hemp) and its constituent, Δ 9-tetrahydrocannabinol or THC, have been classified as Schedule I controlled substances. Seized evidence is tested by forensic laboratories, which verify the identity of the plant through macro- and microscopic evaluation and the

NIST Traceable Reference Material Program for Gas Standards

Ongoing

The Gas Mixture SRM, NTRM, and EPA Protocol Programs provide a mechanism to produce needed calibration gas standards with a well-defined traceability. These mixtures are specified in the Code of Federal Regulations (CFR) to calibrate instruments to be used to monitor regulated emissions. The NTRM

Noise Thermometry

Completed

The project has also created a quantum-based electronic temperature standard that uses the ACJVS in conjunction with measurement of the Johnson noise -- random electrical noise caused by thermal agitation in a conductor -- in resistors at arbitrary temperatures. This Johnson noise thermometry system

Non-Destructive Semiconductor Structure Function and Process Optimization for future Microelectronics Manufacturing at the NIST NSLS-II Beamline for XAFS and Diffraction

Ongoing

This project relies on the existing NIST Synchrotron beamline for X-ray diffraction (XRD), and X-ray absorption spectroscopy (XAS) to improve measurement capabilities. The proposed equipment enhancements will substantially increase sample throughput and sensitivity. Driving the ability to probe

EDMR set up to measure the electrode process of an electrochemical cell.

Operando Measurements of Electrochemical (Charge-transfer) Processes

Ongoing

There are two ways to study a very fast process such as charge transfer. One can use very high-speed measurement that can follow the effect of the process, or one use a method that is sensitive only to the process itself. Either way has its weakness. Many fast measurements can follow the process

Optical/electrical particle measurement system

Ongoing

Intended Impact The results of this work should provide instrument manufacturers with data, methods, and algorithms for enhancing the clarity and accuracy of information their instruments provide to their customers. Users of these instruments (pharma companies) and regulators, will have better

Optical Networking of Superconducting Quantum Computers with Transduction Devices

Ongoing

The team is designing and constructing a quantum optical channel to create remote microwave entanglement for the networking of superconducting quantum computers, expected to be operational by the end of 2026. In this primarily continuous variable approach, the entanglement distribution of optically

Optical and Optoelectronic Materials Characterization

Ongoing

Today's electronics have reached a point where sheer computation power has combined form and function as the key driver of large consumer markets. The demand for portable and pervasive electronics with greater functionality promises significant changes over the next decades in how society interacts

Optical scattering from surfaces

Ongoing

Light Scattering Ellipsometry: The polarization of scattered light can often indicate the source of that scattered light. Using Light Scattering Ellipsometry, whereby the polarization of light scattered into directions out of the plane of incidence is measured for a fixed incident polarization

Optimization of Current and Next Generation Trace Contraband Detection Systems

Ongoing

Ion Mobility Spectrometry (IMS) is widely used for national security and law enforcement, placed at key security checkpoints such as airports and border crossings for the trace detection of drugs and explosives. Its simplicity, ease of operation, portability, and rapid analytical performance

Organic Compounds in Human Serum, Milk, and Urine

Ongoing

Standard Reference Materials (SRMs) have been specifically designed to assist in the quality assurance measurements for compounds found in human fluids. Clinical and biomonitoring laboratories rely on these SRMs for method validation and as control materials during specific analyses. Various human

Overcoming Barriers: Nanoscale Interface Metrology and Electrical Characterization for Advanced Electronics

Ongoing

“The interface is the device,” Herbert Kroemer, 2000 Nobel Laureate. This is even more true today, twenty-three years later, when device dimensions are measured in numbers of atoms rather than numbers of micrometers. Historically, interface problems in the semiconductor industry have been addressed

OWM Laboratory Metrology Training for mass metrology

OWM Training Program: Metrology, Metrication, and More!

Ongoing

OWM offers a variety of in-person, online, and "blended" training classes and materials that provide guidance instruction on national legal metrology standards, weights and measures field inspection procedures, and laws and regulations related to packaging and labeling. OWM provides technical

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