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Additive Manufacturing (AM), the building of 3D objects through layer-by-layer deposition of metal, polymer, or biological materials offers enormous potential
We are working to develop methods and refine experimental techniques to quantify the mechanical properties of soft and biological materials utilizing atomic
Broadband coherent anti-Stokes scattering (BCARS) microscopy is an imaging modality that probes the chemical content and abundance of samples without the
NIST develops cancer measurements by working with our stakeholders to deliver improved measurement methods, data, test materials, interlaboratory testing
Cell counting (or cell enumeration) is one of the most fundamental measurements in biotechnology, from biomanufacturing to medical diagnosis to advanced therapy
Cells derived from different organisms and tissues have been established and are used in bioresearch and for the production of complex biological products. The
The most commonly used cell-based assays for measuring cytotoxicity often show poor reproducibility, require 24 h to complete, and rely on a nonspecific
Huntington disease is a neurodegenerative disease of midlife onset that produces choreic movements and cognitive decline, often accompanied by psychiatric
**Update** As of September 1, 2015, SRM 2366a Cytomegalovirus DNA (TowneΔ147 BAC) for DNA Measurements was made available. The new material is a single
Founded in 2019, this program was motivated by the rapid decriminalization of recreational and medical cannabis by state governments. This has led to extensive
We aim to identify chemometric fingerprints using artificial intelligence methods that reflect the temporal and geographic history of seabirds, and by extension
NIST is developing a portal to enable researchers to mine high-quality proteomic data from phylogenetically diverse species, to identify advantageous biological
As ‘omics moves into industrial and commercial applications, there is a need for quality and process control to ensure safety and efficacy of products and
NIST has taken advantage of recent technological advances to develop polymer microfluidic cell culture systems that provide a level of control over the cellular
Biomarkers play an increasingly important role in disease detection and treatment. As one of the Biomarker Reference Laboratories (BRLs) in the Early Detection
In conjunction with NCI/NIH, NIST is developing methods to improve mRNA amplification from small biological samples. Typical sample processing requires
The use of metabolite, lipid, and protein profiles for systems biology, biomedical research, and clinical applications has risen dramatically over recent years
Chronic kidney disease (CKD) is a growing problem in the U.S., and current estimates suggest that more than 20 million Americans are affected by this disease
The accuracy of clinical diagnostic measurements is essential for reliable diagnosis and cost-effective treatment of disease. NIST's involvement in reference
The National Institute of Standards and Technology (NIST), in collaboration with the Centers for Disease Control and Prevention (CDC), has developed Standard
As part of a multi-year interagency agreement between the National Institute of Standards and Technology (NIST) and the Centers for Disease Control and
The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH) Office of Dietary Supplements (ODS)
Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR platforms for