Projects/Programs

Displaying 1 - 25 of 82

Additive Manufacturing and Inkjet Printing

Ongoing

Additive Manufacturing (AM), the building of 3D objects through layer-by-layer deposition of metal, polymer, or biological materials offers enormous potential

Atomic Force Microscopy Methods for Soft Materials

Ongoing

We are working to develop methods and refine experimental techniques to quantify the mechanical properties of soft and biological materials utilizing atomic

Bioimaging

Ongoing

Our goal is to develop methods and materials for imaging-based characterization of molecular signatures that occur during cellular proliferation

Broadband Coherent Anti-Stokes Raman Scattering (BCARS) Microscopy

Ongoing

Broadband coherent anti-Stokes scattering (BCARS) microscopy is an imaging modality that probes the chemical content and abundance of samples without the

Calibration Services: High-Dose Dosimetry

Ongoing

The activities described here support the application of high-dose, high-energy ionizing radiation for a variety of industrial processes. The largest

Cancer Biomarker Measurements and Collaborations

Ongoing

NIST develops cancer measurements by working with our stakeholders to deliver improved measurement methods, data, test materials, interlaboratory testing

Cell Counting for Cell Therapies

Ongoing

Cell counting (or cell enumeration) is one of the most fundamental measurements in biotechnology, from biomanufacturing to medical diagnosis to advanced therapy

Cell Line Authentication

Ongoing

Cells derived from different organisms and tissues have been established and are used in bioresearch and for the production of complex biological products. The

Cell-based Assay for Mechanistically-based Prediction of Cytoxicity

Ongoing

The most commonly used cell-based assays for measuring cytotoxicity often show poor reproducibility, require 24 h to complete, and rely on a nonspecific

Certification of Standard Reference Material 2393 for the CAG repeats of Huntington Disease

Ongoing

Huntington disease is a neurodegenerative disease of midlife onset that produces choreic movements and cognitive decline, often accompanied by psychiatric

Certification of a Standard Reference Material for Cytomegalovirus (CMV)

Ongoing

**Update** As of September 1, 2015, SRM 2366a Cytomegalovirus DNA (TowneΔ147 BAC) for DNA Measurements was made available. The new material is a single

Chemical Foundations for a Cannabis Breathalyzer

Ongoing

Founded in 2019, this program was motivated by the rapid decriminalization of recreational and medical cannabis by state governments. This has led to extensive

Classification Methods for the NIST Biorepository

Ongoing

We aim to identify chemometric fingerprints using artificial intelligence methods that reflect the temporal and geographic history of seabirds, and by extension

Comparative Mammalian Proteome Aggregator Resource (CoMPARe) Program

Ongoing

NIST is developing a portal to enable researchers to mine high-quality proteomic data from phylogenetically diverse species, to identify advantageous biological

Consistency Analysis and Uncertainty in ‘omic Data

Ongoing

As ‘omics moves into industrial and commercial applications, there is a need for quality and process control to ensure safety and efficacy of products and

Controlling Microfluidic Cell Cultures

Ongoing

NIST has taken advantage of recent technological advances to develop polymer microfluidic cell culture systems that provide a level of control over the cellular

Development of Biomarker-based Systems for Cancer Detection and Therapy

Ongoing

Biomarkers play an increasingly important role in disease detection and treatment. As one of the Biomarker Reference Laboratories (BRLs) in the Early Detection

Development of Enhanced mRNA Amplification Using Microfluidics

Ongoing

In conjunction with NCI/NIH, NIST is developing methods to improve mRNA amplification from small biological samples. Typical sample processing requires

Development of NIST Reference Materials for Untargeted Metabolomics, Lipidomics and Proteomics

Ongoing

The use of metabolite, lipid, and protein profiles for systems biology, biomedical research, and clinical applications has risen dramatically over recent years

Development of Reference Measurement Procedures and Reference Materials for Creatinine

Ongoing

Chronic kidney disease (CKD) is a growing problem in the U.S., and current estimates suggest that more than 20 million Americans are affected by this disease

Development of Reference Methods and Reference Materials for Clinical Diagnostic Markers

Ongoing

The accuracy of clinical diagnostic measurements is essential for reliable diagnosis and cost-effective treatment of disease. NIST's involvement in reference

Development of SRM 2669 for Accurate Assessment of Arsenic Exposure

Ongoing

The National Institute of Standards and Technology (NIST), in collaboration with the Centers for Disease Control and Prevention (CDC), has developed Standard

Development of SRMs 2668 and 3668 for Accurate Assessment of Exposure to Toxic Elements and Anions

Ongoing

As part of a multi-year interagency agreement between the National Institute of Standards and Technology (NIST) and the Centers for Disease Control and

Dietary Supplements Laboratory Quality Assurance Program (DSQAP)

Ongoing

The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH) Office of Dietary Supplements (ODS)

Digital PCR

Ongoing

Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR platforms for

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