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Metagenomic Next Generation Sequencing (mNGS) promises to revolutionize infectious disease diagnostics. However, the analytical performance of this technology
Cells are being used in drug discovery, therapeutics development, biomedical research, and biotechnological and medical applications. However, the measurement
NIST develops cancer measurements by working with our stakeholders to deliver improved measurement methods, data, test materials, interlaboratory testing
Part of the Genome in a Bottle Consortium hosted by NIST dedicated to authoritative characterization of benchmark cancer genomes. Complements NIST's current DNA
The misidentification of cell lines has been a problem in the scientific community for the past 50 years. Methods are now in place to genotype human cell lines
NIST is developing a portal to enable researchers to mine high-quality proteomic data from phylogenetically diverse species to identify advantageous biological
Initially the Comparative Mammalian Proteome Aggregator Resource (CoMPARe) Program will generate proteomic data from sera from 25 different species that
The development of new platforms for characterization of complex microbial samples are hampered by lack of reproducibility and comparability across different
Currently, forensic DNA profiles consist of size measurements which are interpreted as the number of repeat units at STR (short tandem repeat) markers. Due to
Consortium hosted by NIST dedicated to authoritative characterization of benchmark human genomes. Sign up for General GIAB and Analysis Team email lists
To identify new biomarkers that may serve as disease indicators and to understand biologically relevant properties of the human gut microbiome, we need
Confidence in total or viable microbial cell counting methods is lacking, due in part to a dearth of relevant reference materials. NIST has developed a living
Reference materials (RMs) consisting of whole microbial cells characterized for total cell number and total DNA are needed to evaluate and compare cell counting
NIST supports the National Cancer Institute (NCI) Early Detection Research Network (EDRN) as a Biomarker Reference Laboratory by efficiently validating the
Flow cytometry is used to analyze individual cells to understand the proteins, nucleic acids and other biomolecules they have or produce, and to analyze groups
The National Institute of Standards and Technology Genome Editing Consortium addresses the measurements and standards needed to increase confidence and lower
Genome Editing technologies have transformed the potential of biosciences and biotechnology, by providing precision engineering tools that enable modifications
NIST Standard Reference Material SRM ® 2373 was developed to improve the measurements of the HER2 gene amplification in DNA samples. SRM ® 2373 consists of
NIST and FDA are co-developing DNA-based materials for mixed microbial detection. Our annual workshop brings together private and public interests to discuss
The NIST Regenerative Medicine and Advanced Therapies (RMAT) laboratory programs are focused on developing innovative measurement assurance solutions and
The global response to COVID-19 is leading to rapid advances in diagnostic, surveillance, and vaccine and therapeutic development. A critical measurement
Control over engineering and measuring single cells is an emerging capability of value to increase confidence the sectors of engineering biology, regenerative