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Material Measurement Laboratory

Projects/Programs

Displaying 351 - 375 of 568
autonomous vehicles on a road

NIST and Autonomous Vehicles

Ongoing
Why Autonomous Vehicles? Autonomous vehicles are projected to influence key aspects of everyday life including transportation, goods delivery, manufacturing, public safety, and security. In addition, the autonomous vehicle sector is a vastly inter-disciplinary field with subject areas including
NIST Biorepository Freezers

The NIST Biorepository

Ongoing
The NBSB was established in 1979 at NIST in Gaithersburg, MD with a pilot project archiving human liver samples associated with collections through the Environmental Protection Agency (EPA). New collaborations and banking projects were established including the National Oceanic and Atmospheric

The NIST Chemistry Webbook

Ongoing
Intended Impact It is part of NIST's mission to distribute Standard Reference Data to scientists, engineers, educators, and the general public. The NIST Chemistry WebBook is intended to help fulfill NIST's mission by distributing such data over the Internet. Objective Develop a web site

NIST Combinatorial Methods Center (NCMC)

Completed
Established in 2002, the NCMC combines pioneering research and customer engagement to foster wide-spread adaptation of combinatorial and high-throughput methodologies. NCMC research addresses key challenges faced by polymer researchers who want to employ combi. In particular, the NCMC creates new
Conceptual Art of Gas Molecules Adsorbed in a Zeolite Adsorbent

NIST Data Resources for Adsorption

Ongoing
NIST/ARPA-e Database of Novel and Emerging Adsorbent Materials A centralized resource for the scientific community to find and compare single- and multi-component adsorption isotherms reported in the literature. The database sorts data according to adsorbent material, adsorbate species

NIST/EDRN Cancer Biomarker Collaboration

Completed
Our lab is one of the EDRN Biomarker Reference Laboratories working with the EDRN discovery labs to improve the quality of the measurements done on new cancer biomarkers for early detection of cancer and for cancer risk. TECHNICAL APPROACH Evaluate current assays used for detection of cancer
Flow Cytometry Consortium

NIST Flow Cytometry Standards Consortium 

Ongoing
Advances in cell and gene-based therapeutics as well as other regenerative medicine products have increased the need for high quality, robust, and validated measurements for cell characterization. Flow cytometry, including imaging cytometry, has emerged as an important platform due to its ability to
Montage of photographs depicting eggs, almonds, grain, milk, strawberries, fish, peanuts, and soybeans.

NIST Food Protein Allergen Program

Ongoing
Food allergen management is an increasingly important economic and public health concern; therefore, accurate and reliable allergen measurements are a crucial component of the management pathway. Traditional methods for food allergen detection are based on immunoassay techniques and are linked to a
photo collage of meats, cheese, eggs, fish, and shellfish

NIST Food Safety Program

Ongoing
The Food Safety Program at the National Institute of Standards and Technology (NIST) provides advanced analytical chemistry and quantitative biology to ensure that food is free of contaminants and allergens and is authentic, promoting U.S. manufacturers’ participation in domestic and foreign markets

NIST Genome Editing Consortium: Working Group 1 - Specificity Measurements

Ongoing
Genome editing technologies are able to produce DNA sequence changes of a variety of sizes and at a variety of frequencies in a population of edited cells. Having increased confidence in reliably detecting the sequences generated by a genome editing process was a need area identified. Project 1

NIST Genome Editing Consortium: Working Group 2 - Data & Metadata

Ongoing
Develop a metadata schema for genome editing experiments Develop a way of curating and entry that is low burden for user Release control data with linked metadata PROGRESS Phase1 metadata entries and templates completed In process of compiling and testing use cases, user interfaces, and
Genome editing technologies

NIST Genome Editing Consortium

Ongoing
Targeted genome editing , a method used to alter the DNA of living cells at desired locations, is poised to revolutionize science and medicine. To fight diseases, novel genome edited therapeutics, including those for use in regenerative medicine and infectious diseases, are being developed. Many

NIST Genome Editing Lexicon

Ongoing
The definitions are worded with the intention that additional context may be added with supplementary language when they are used. It is also recognized that genome editing is a rapidly evolving biotechnology and additional terms and definitions will be needed as genome editing technologies mature

NIST Genome Editing Program

Ongoing
For genome editing systems to reach their full potential in research and commercial products, new measurement tools, capabilities, and standards must be developed to efficiently implement and assess the performance of these editing technologies, as well as to evaluate the utility of resulting
HER2 SRM Unit and Individual Components

NIST HER2 Genomic DNA Standard Reference Material, SRM® 2373

Ongoing
The amplification of the gene for HER2 occurs in approximately 20 to 25% of breast cancers. The accurate measurement of this biomarker is important for the proper treatment with anti-HER2 therapeutics. Clinical laboratories are beginning to utilize accurate and sensitive diagnostic tests based on

NIST LabCAS: Data Driven Science Architecture and Resource

Ongoing
Biological data lie at the heart of innovation and artificial intelligence (AI) advances in the emerging biotechnology sector and serve as key strategic resources for achieving major breakthroughs in biomanufacturing, as summarized by the National Security Commission on Emerging Biotechnology's
NIST Foundry for Living Measurement Systems

NIST Living Measurement Systems Foundry

Ongoing
To enable the production of high-throughput, high-quality data that meets the rapidly evolving needs of current and future stakeholders, NIST has established an automation facility for the growth, manipulation, sample preparation, and measurement of engineered microbes. The core of the facility

NIST Materials Resource Registry

Ongoing
The MRR is a comprehensive inventory of high-level data collections, repositories, databases, tools, software, and services useful to materials research and design but located anywhere in the world. Its specialization for Materials Science is in the domain-specific metadata and vocabulary it can

NIST Materials-focused Empirical Potentials Repositories and Efforts

Ongoing
SOFT MATTER WebFF: Force-field repository for organic and soft materials Frederick R. Phelan Jr., 1 and Huai Sun 2 1Materials Science and Engineering Division, NIST, Gaithersburg, MD 20899 2Aeon Technology Inc. and School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University
Microbial Strain

NIST Microbial Strain Collection

Ongoing
Microorganisms of interest include but are not limited to those relevant to: biomanufacturing of advanced therapy products; rapid microbial testing; microbial therapeutics (e.g., live biotherapeutic products, probiotics, and fecal microbiota transplantations (FMTs)); infectious disease
NISTmAb RM8671 vial and 3D printed model

NIST Monoclonal Antibody Reference Material 8671

Ongoing
The NISTmAb material is a recombinant humanized IgG1κ expressed in murine suspension culture. It is an »150 kDa homodimer of two identical light chains and two identical heavy chains linked through both inter- and intra-chain disulfide bonds. The protein has low abundance post-translational
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NIST Ocean Carbon Measurements

Ongoing
NIST is committed to sustaining the quality of ocean carbon measurements by developing capabilities to provide certified reference materials for the ocean carbonate system measurements and by conducting research to understand fundamental elements of the ocean carbon thermodynamic system. NIST Ocean
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