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Gaithersburg

Content-Based Access to Unstructured Information

This project uses community evaluations to build the infrastructure required to evaluate system effectiveness on information access tasks. In particular, the

Carbon Nanotube Reference Materials

Single-wall carbon nanotubes are an important class of carbon nanomaterials with significant potential for commercial applications. The National Institute of

OOF

The OOF project seeks to provide flexible software for finite-element modeling the behavior of real microstructures, with meshes derived from micrographs.

Measurement and Sampling Standards

The use of standards is considered a critical component in the assurance of analytical quality, allowing reliable measures of detection limits, accuracy, and

A Comparison of WD-EPMA Heterogeneity Testing Procedures

The heterogeneity of the four elements in a TiAl(NbW) SRM 2061 alloy were determined from five specimens with WD-EPMA (wavelength dispersive – electron probe

Electron Ionization Library Component of the NIST/EPA/NIH Mass Spectral Library and NIST GC Retention Index Database

The National Institute of Standards and Technology (NIST) has developed and maintains evaluated libraries of reference data for the identification of chemicals

Performance Metrics for Proteomics

In collaboration with the National Cancer Institute's Clinical Proteomic Technologies for Cancer (CPTC), NIST researchers are developing specific and

Cell-based Assay for Mechanistically-based Prediction of Cytoxicity

The most commonly used cell-based assays for measuring cytotoxicity often show poor reproducibility, require 24 h to complete, and rely on a nonspecific

Solvation Thermodynamics

Using data from REFPROP 8.0, thermodynamic quantities for the self-solvation of 76 pure fluids were computed. These quantities are valuable for comparison to

Figure with data points and lines, with the x axis labeled “unreliability” and the y axis labeled “error”.

Virtual Measurements

Compared with conventional, physical measurements, the cost of computational modeling continues to drop. This has driven many industries to incorporate

Ammunition metal box with explosives sticker.

Explosives Decomposition Chemistry

High-energy materials are commonly used as military explosives and as advanced propellants. The detailed chemical reactions responsible for detonation

Finite Element Model and Color Mapping of Cranium

Toothsome Research: Deducing the Diet of a Prehistoric Hominid

February 10, 2009

In an unusual intersection of materials science and anthropology, researchers from the National Institute of Standards and Technology (NIST) and The George...

Staff gather, standing on the steps for a large group photo

Mass Spectrometry Data Center Staff

Group Leader Wallace, William E. Dr. [info...] Principal Investigator Stein, Stephen E. Dr. [info...] Andriamaharavo, Nirina Rabe - [info...

The NIST Chemistry Webbook

The NIST Chemistry WebBook is a site on the Internet ( http://webbook.nist.gov/) that provides convenient access to a variety of physical and chemical property

Metrology and Standards for Canine Olfactory Detection of Explosives

As part of a multi-year interagency agreement between the Office of Standards of the Department of Homeland Security and NIST, NIST is developing measurement

Photograph of a toy race car, toy monster truck with snail face, and sagging toy bridge.

Support of the Consumer Product Safety Improvement Act (CPSIA) of 2008 - Lead in Paint on Toys

After enactment of the CPSIA, a collaboration was established between the Consumer Product Safety Commission (CPSC) and NIST for the purpose of developing tools

Support of Industry Compliance with the EU Directive on Restriction of Certain Hazardous Substances (RoHS)

The Chemical Sciences Division is involved in development of standards and reference materials for restricted hazardous substances through participation in

CCQM Activities in the Inorganic Analysis Working Group and the Electrochemical Analysis Working Group

NIST maintains an active role in these two CCQM working groups, participating in international key comparisons and pilot studies, organizing new studies, and

Determinations of Boron Deposit Quality by Neutron Depth Profiling

Straw detectors are a new concept in position-sensitive neutron detectors recently developed by Proportion Technology Inc. The detectors are especially valuable

Photograph showing labeled units of SRM 1649 Urban Dust and SRM 1649a Urban Dust.

Measurements and Standards for Contaminants in Environmental Samples

For the past 40 years NIST has developed SRMs for the determination of inorganic and organic contaminants in environmental matrices such as sediments/soils

Certification of Three Soil SRMs for Inorganic Environmental Measurements

Analysis of soils for metals and other elements is essential in assessing environmental compliance and the impacts of potentially toxic elements on human

Fundamental Interaction Mechanisms of Engineered Nanomaterials with DNA

We utilized isotope-dilution liquid chromatography/mass spectrometry (LC/MS) to determine the levels of the oxidatively damaged DNA bases, 8

Development of Biomarker-based Systems for Cancer Detection and Therapy

Biomarkers play an increasingly important role in disease detection and treatment. As one of the Biomarker Reference Laboratories (BRLs) in the Early Detection

Photograph of a packaged unit of SRM 2700 Hexavalent chromium in Contaminated Soil (low Level)

Standard Reference Materials for Hexavalent Chromium in Contaminated Soil

Significant environmental remediation efforts are being conducted to address the hazards posed by the long-term terrestrial disposal of hexavalent chromium in

Multidimensional Chromatography

Both comprehensive two-dimensional gas chromatography (GCxGC) and comprehensive two-dimensional liquid chromatography (LCxLC) have emerged as powerful tools

Standard Solution SRMs Provide Traceability for Millions of Measurements

For decades, NIST has provided the SRM 3100 series single-element standard solutions. The certified values are traceable to the International System of Units

Evaluation of Independent High-Precision Assay Procedures for a High-Purity Primary Standard Reagent

NIST assigns assay values for a suite of high-purity reagents using two techniques: coulometry and titrimetry. Coulometry is based on Faraday's Laws of

pH Metrology

The pH metrology program supports traceability for pH measurements. This traceability rests on primary pH measurements in an ideal electrochemical cell (Harned

Figure with five interlocking puzzle pieces representing different aspects of the measurement process.

Improving High-Performance Inductively-Coupled Plasma Optical Emission Spectrometry (HP-ICP-OES) Through Exact Matching

Using high-performance inductively coupled plasma optical emission spectrometry (HP‑ICP-OES), relative expanded uncertainties on the order of 0.2 % can be

Study of Microheterogeneity in Solid Reference Materials

Microbeam X-ray fluorescence (µXRF) has been used nondestructively to investigate elemental heterogeneity by constructing two-dimensional maps of elemental

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