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Search Publications by: Nancy Lin (Fed)

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Displaying 26 - 50 of 69

Solution-based functionalization of gallium nitride nanowires for protein sensor development

April 17, 2014
Author(s)
Albert Davydov, Elissa H. Williams, Vladimir P. Oleshko, Kristen L. Steffens, Igor Levin, Nancy J. Lin, Kristine A. Bertness, Amy Manocchi, M V. Rao, John A. Schreifels
A solution-based functionalization method for the specific and selective attachment of the streptavidin (SA) protein to gallium nitride (GaN) nanowires (NWs) is presented. By exploiting streptavidin's strong affinity for its ligand biotin, SA

Effects of dual antibacterial agents MDPB and nano-silver in primer on microcosm biofilm, cytotoxicity and dentin bond properties

February 1, 2013
Author(s)
Ke Zhang, Lei Cheng, Satoshi Imazato, Joseph M. Antonucci, Nancy Lin, Sheng Lin-Gibson, Yuxing Bai, Hockin H. Xu
Objectives: Secondary caries at restoration margins is the main reason for restoration failure. Antibacterial bonding agents are promising to inhibit biofilm acids at the tooth-restoration interfaces. The objective of this study was to investigate the

Selective Streptavidin Bioconjugation on Si and SiC nanowires for Biosensor Applications.

January 14, 2013
Author(s)
Elissa H. Williams, John A. Schreifels, Mulpuri V. Rao, Albert Davydov, Vladimir P. Oleshko, Nancy J. Lin, Kristen L. Steffens, Sergiy Krylyuk, Kristine A. Bertness, Amy Manocchi, Yaroslav Koshka
A functionalization method for the specific and selective immobilization of the streptavidin (SA) protein on semiconductor nanowires (NWs) was developed. Silicon (Si) and silicon carbide (SiC) NWs were functionalized with 3-aminopropyltriethoxysilane

Selective Streptavidin Bioconjugation on Si, SiC, and GaN Nanowires for Biosensor Applications.

October 19, 2012
Author(s)
Elissa H. Williams, John A. Schreifels, Mulpuri V. Rao, Albert Davydov, Vladimir Oleshko, Nancy Lin, Kristen L. Steffens, Sergiy Krylyuk, Kristine A. Bertness, Amy Manocchi, Yaroslav Koshka
A functionalization method for the specific and selective immobilization of the streptavidin (SA) protein on semiconductor nanowires (NWs) was developed. Silicon (Si), silicon carbide (SiC), and gallium nitride (GaN) NWs were functionalized with 3

Effect of Polymer Degree of Conversion on Streptococcus mutans Biofilms

October 5, 2012
Author(s)
Alison M. Kraigsley, Kathy Tang, John A. Howarter, Katrice Lippa, Sheng Lin-Gibson, Nancy Lin
The effects of key material properties of polymeric composite restorations on cariogenic oral biofilms are needed to provide insight into the materials' role in recurrent caries. The objective of this study was to quantify the effects of degree of

Antibacterial nanocomposites containing amorphous calcium phosphate and silver nanoparticles with different filler levels

May 7, 2012
Author(s)
Lei Cheng, Michael D. Weir, Hockin H. Xu, Joseph M. Antonucci, Nancy Lin, Sheng Lin-Gibson, Sarah M. Xu, Xuedong Zhou
A dental composite containing amorphous calcium phosphate nanoparticles (NACP) was developed that released high levels of calcium (Ca) and phosphate (PO4) ions and possessed acid neutralization capability. There has been little study on incorporation of

Positively-charged Dimethacrylates to Reduce Bacterial Attachment

March 30, 2012
Author(s)
Nancy J. Lin, Joseph M. Antonucci, Diana N. Zeiger, Sheng Lin-Gibson, Kathy Tang
The widespread incidence of recurrent tooth decay (caries) highlights the need for improved dental restorative materials. Caries are most frequently caused by acid-producing bacterial biofilms. One approach for developing biomaterials with reduced

Antibacterial amorphous calcium phosphate nanocomposite with quaternary ammonium salt and silver nanoparticles

February 2, 2012
Author(s)
Nancy J. Lin, Lei Cheng, Michael D. Weir, Hockin H. Xu, Joseph M. Antonucci, Alison M. Kraigsley, Sheng Lin-Gibson, Xuedong Zhou
Objectives. Calcium and phosphate ion-releasing resin composites are promising for remineralization; however, so far there has been no report on imparting a potent antibacterial capability to these composites. The objectives of this study were to

Synthesis and characterization of antimicrobial dimethacrylates containing quaternary ammonium functionalities for dental and biomedical applications

October 27, 2011
Author(s)
Joseph M. Antonucci, Diana N. Zeiger, Sheng Lin-Gibson, Bruce O. Fowler, Nancy J. Lin
The widespread incidence of recurrent caries has resulted in the need for improved dental restorative materials, including effective antibacterial, polymeric dental materials. Compounds with quaternary ammonium groups are known to reduce bacterial growth

Mechanics behind 4-D interferometric measurement of biofilm mediated tooth decay

May 16, 2011
Author(s)
Michael S. Waters, Bin (. Yang, Nancy J. Lin, Sheng Lin-Gibson
Evaluating the efficacy of dental materials to protect human teeth requires the capacity to measure tooth accurately and precisely decay. Current practices for determining tooth decay are destructive, qualitative to lowly quantitative, and/or measure bulk

In situ Formation of Silver Nanoparticles in Photocrosslinking Polymers

February 2, 2011
Author(s)
Yajun Cheng, Diana N. Zeiger, John A. Howarter, Xinran Zhang, Nancy Lin, Joseph M. Antonucci, Sheng Lin-Gibson
Nanocomposites of difunctional methacrylate polymer/silver nanoparticles have been synthesized by coupling photoinitiated free radical polymerization with in situ silver ion reduction. A polymerizable methacrylate bearing a secondary amino function group

Controlled in situ Nanocavitation in Polymeric Materials

January 18, 2011
Author(s)
Yajun Cheng, Joseph M. Antonucci, Steven Hudson, Nancy Lin, Xinran Zhang, Sheng Lin-Gibson
A new strategy to produce polymer-inorganic composites with ultra low volume shrinkage has been developed. Small amount of cavitation agent, acetone dicarboxylic acid (ADCA), was introduced into acrylate-glass composites and decomposed in situ to carbon

Effects of Polymeric Nanogratings on Cell Orientation

December 30, 2010
Author(s)
Nancy J. Lin, Sheng Lin-Gibson, Jirun Sun, Yifu Ding
Surface topography is known to play a critical role in the biological response to materials, with surface features on the order of both microns and nanometers altering cell response, including morphology, adhesion, cytoskeletal orientation, and gene

Cell Contact Guidance in Response to Nanopattern Shape and Height

October 18, 2010
Author(s)
Sheng Lin-Gibson, Jirun Sun, Nancy J. Lin, Jing N. Zhou, Hyun W. Ro, Christopher L. Soles, Marcus T. Cicerone, Yifu Ding
Understanding the correlation between cell contact guidance (CG) and nanoscale surface features is vital in designing advanced medical devices to manipulate cell behaviors. Nanoscale surface features that mimic extracellular matrix are critical

PHOTOPOLYMERIZED DIMETHACRYLATE POLYMERS CONTAINING IN SITU GENERATED SILVER NANOPARTICLES

August 21, 2010
Author(s)
Yajun Cheng, Xinran Zhang, Diana N. Zeiger, Nancy Lin, Joseph M. Antonucci, Sheng Lin-Gibson
Polymeric nanocomposites containing silver are known to exhibit antibacterial activity. Here we demonstrate the synthesis and characterization of dimethacrylate/silver nanocomposites by coupling photopolymerization with in situ silver ion reduction. An

Thermodynamic Underpinnings of Cell Alignment on Controlled Topographies

August 17, 2010
Author(s)
Yifu Ding, Jirun Sun, Hyun W. Ro, Zhen Wang, Jing N. Zhou, Nancy J. Lin, Sheng Lin-Gibson, Marcus T. Cicerone, Christopher L. Soles
Cells sense and respond to the chemical, topographical, and mechanical features of their substrate and extracellular matrix. Shape and locomotive response to these features is termed contact guidance (CG) and is of vital importance in understanding many

Novel Dimethacrylates with Quaternary Ammonium Functionalities for Reduced Bacteria Adhesion

April 1, 2010
Author(s)
Nancy J. Lin, Joseph M. Antonucci, Diana N. Zeiger, Kathy Tang, Bruce O. Fowler, Sheng Lin-Gibson
Biofilm growth and secondary caries have resulted in the failure of many dental composite restorations. One approach to address this issue is the modification of dental materials to reduce bacterial adhesion and biofilm growth. Quaternary ammonium salts