Selective Streptavidin Bioconjugation on Si and SiC nanowires for Biosensor Applications.

Published

January 14, 2013

Author(s)

Elissa H. Williams, John A. Schreifels, Mulpuri V. Rao, Albert Davydov, Vladimir P. Oleshko, Nancy J. Lin, Kristen L. Steffens, Sergiy Krylyuk, Kristine A. Bertness, Amy Manocchi, Yaroslav Koshka

Abstract

A functionalization method for the specific and selective immobilization of the streptavidin (SA) protein on semiconductor nanowires (NWs) was developed. Silicon (Si) and silicon carbide (SiC) NWs were functionalized with 3-aminopropyltriethoxysilane (APTES) and subsequently biotinylated for the conjugation of SA. Field-emission scanning electron microscopy (FESEM), X-ray photoelectron spectroscopy (XPS), high-resolution transmission electron microscopy (HRTEM), atomic force microscopy (AFM), and fluorescence microscopy were utilized to study each functionalization step on the Si and SiC NWs.

Citation

Journal of Materials Research

Volume

28

Issue

1

Pub Type

Journals

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DOI Link

Keywords

biosensor, nanowires, surface chemistry

Citation

Williams, E. , Schreifels, J. , Rao, M. , Davydov, A. , Oleshko, V. , Lin, N. , , K. , Krylyuk, S. , Bertness, K. , Manocchi, A. and Koshka, Y. (2013), Selective Streptavidin Bioconjugation on Si and SiC nanowires for Biosensor Applications., Journal of Materials Research, [online], https://doi.org/10.1557/jmr.2012.283 (Accessed October 8, 2025)